STUDIES ON TH E ACTIVITIES OF DRU G METABOLIZING ENZYMES IN LUN G AN D KIDNEY MICROSOMES OF RAT

Benay Can Eke

doi:10.1501/Eczfak_0000000383

TR EN

SIÇAN AKCİĞERİ VE BÖBREĞİ MİKROZOMLARINDA İLAÇ METABOLİZE EDEN ENZİMLERİN AKTİVİTELERİ ÜZERİNE ÇALIŞMALAR

Abstract

Bu çalışmada sıçan akciğer ve böbreği mikrozomal fraksiyonlarında sitokrom P450'ye bağımlı enzim sistemi üyelerinden 7-etoksiresorufın-O-etilaz (EROD), 7-pentoksiresorufın-O-etilaz (PROD), eritromisin-N-demetilaz (ERND), kumarin 7-hidroksilaz (Coh) ve p-nitrofenol hidroksilaz(PNP) enzim aktiviteleri için optimum pH, protein miktarı, substrat konsantrasyonu ve inkübasyon süresi saptandı. Sıçan akciğer ve böbrek mikrozomlarında bu enzim aktiviteleri için farklı reaksiyon koşullarına gereksinim olduğu saptandı.

Keywords

Sıçan, akciğer, böbrek, monooksijenaz, mikrozom

Details

Primary Language

English

Subjects

-

Journal Section

-

Authors

Benay Can Eke This is me

Publication Date

March 1, 2003

Submission Date

March 1, 2003

Acceptance Date

-

Published in Issue

Year 2003 Volume: 32 Number: 1

DOI

https://doi.org/10.1501/Eczfak_0000000383

IZ

https://izlik.org/JA69TN78GM

Cite

RIS / Bibtex

APA

Can Eke, B. (2003). STUDIES ON TH E ACTIVITIES OF DRU G METABOLIZING ENZYMES IN LUN G AN D KIDNEY MICROSOMES OF RAT. Journal of Faculty of Pharmacy of Ankara University, 32(1), 1-18. https://doi.org/10.1501/Eczfak_0000000383

AMA

1.Can Eke B. STUDIES ON TH E ACTIVITIES OF DRU G METABOLIZING ENZYMES IN LUN G AN D KIDNEY MICROSOMES OF RAT. J. Fac. Pharm. Ankara. 2003;32(1):1-18. doi:10.1501/Eczfak_0000000383

Chicago

Can Eke, Benay. 2003. “STUDIES ON TH E ACTIVITIES OF DRU G METABOLIZING ENZYMES IN LUN G AN D KIDNEY MICROSOMES OF RAT”. Journal of Faculty of Pharmacy of Ankara University 32 (1): 1-18. https://doi.org/10.1501/Eczfak_0000000383.

EndNote

Can Eke B (March 1, 2003) STUDIES ON TH E ACTIVITIES OF DRU G METABOLIZING ENZYMES IN LUN G AN D KIDNEY MICROSOMES OF RAT. Journal of Faculty of Pharmacy of Ankara University 32 1 1–18.

IEEE

[1]B. Can Eke, “STUDIES ON TH E ACTIVITIES OF DRU G METABOLIZING ENZYMES IN LUN G AN D KIDNEY MICROSOMES OF RAT”, J. Fac. Pharm. Ankara, vol. 32, no. 1, pp. 1–18, Mar. 2003, doi: 10.1501/Eczfak_0000000383.

ISNAD

Can Eke, Benay. “STUDIES ON TH E ACTIVITIES OF DRU G METABOLIZING ENZYMES IN LUN G AN D KIDNEY MICROSOMES OF RAT”. Journal of Faculty of Pharmacy of Ankara University 32/1 (March 1, 2003): 1-18. https://doi.org/10.1501/Eczfak_0000000383.

JAMA

1.Can Eke B. STUDIES ON TH E ACTIVITIES OF DRU G METABOLIZING ENZYMES IN LUN G AN D KIDNEY MICROSOMES OF RAT. J. Fac. Pharm. Ankara. 2003;32:1–18.

MLA

Can Eke, Benay. “STUDIES ON TH E ACTIVITIES OF DRU G METABOLIZING ENZYMES IN LUN G AN D KIDNEY MICROSOMES OF RAT”. Journal of Faculty of Pharmacy of Ankara University, vol. 32, no. 1, Mar. 2003, pp. 1-18, doi:10.1501/Eczfak_0000000383.

Vancouver

1.Benay Can Eke. STUDIES ON TH E ACTIVITIES OF DRU G METABOLIZING ENZYMES IN LUN G AN D KIDNEY MICROSOMES OF RAT. J. Fac. Pharm. Ankara. 2003 Mar. 1;32(1):1-18. doi:10.1501/Eczfak_0000000383

SIÇAN AKCİĞERİ VE BÖBREĞİ MİKROZOMLARINDA İLAÇ METABOLİZE EDEN ENZİMLERİN AKTİVİTELERİ ÜZERİNE ÇALIŞMALAR

Abstract

Keywords