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FATTY ACID COMPOSITION OF RED BLOOD CELL MEMBRANE PHOSPHATIDYLETHANOLAMINE AND PHOSPHATIDYLCHOLINE IN RAT, RABBIT, HUMAN AND DOG

Year 2002, , 169 - 182, 01.09.2002

Bilgehan Doğru Pekiner

https://doi.org/10.1501/Eczfak_0000000374

Abstract

RBC (red blood cell) membrane fatty acid percentages in PE (phosphatidylethanolamine) and PC (phosphatidylcholine) in different species like rats, rabbits, humans and dogs were measured and compared. The major fatty acids of membrane PE and PC in the species were same as C16:0, C18:1,, C18:1, C18:2and C20:4. SFAs (Saturatedfatty acids) (C16:0, C18:0, and C20:0) were lower in PE but higher in PC in all species in RBC membrane. Arachidonate (C20:4 ) and PUFAs (polyunsaturated fatty acid) (C18:2, C18:3 and C20:4) were higher in PE than PC. PC also had relatively high PUFA content. C20:4 was a prominent fatty acid of PE in rat, human and dog except rabbit. C18:22 was the prominent fatty acid in the rabbit. MUFA (monounsaturated fatty acid) (C16:1,C18:1 C18:1, C20:1 and C22:1) percentage was also higher in PE than PC. C18:1 was found considerably higher than C16:1 in all species. LCPUFAs (long chain polyunsaturated fatty acids) (C22:4, and C22:6 were significantly lower in the species PE and PC. Among LCPUFA, C22:6 was high in human RBC membrane PE and was not detected in dog

Keywords

fatty acids RBC membrane PE PC rat rabbit human dog

SIÇAN, TAVŞAN, İNSAN VE KÖPEK ERİTROSİT MEMBRANI FOSFATİDİLETANOLAMİN VE FOSFATİDİLKOLİNİN YAĞ ASİDİ KOMPOZİSYONU

Year 2002, , 169 - 182, 01.09.2002

Bilgehan Doğru Pekiner

https://doi.org/10.1501/Eczfak_0000000374

Abstract

Rat, tavşan, insan ve köpek gibi farklı türlerin kırmızı kan hücreleri fosfatidiletanolamin (PE) ve fosfatidilkolini (PC) yağ asitleri tayin edilmiş ve karşılaştırılmıştır. Türlerin membran PE ve PC yağ asitleri başlıca C16:0, C18:0, C18:1, Q18:2 ve C20:4 dir. Doymuş yağ asitleri (SFA) (C18:0, C18:0, ve C20:0) bütün türlerde PE de düşük ancak PC de yüksek düzeydedir. Arakidonat (C20:4 ) ve çoklu doymamış yağ asitleri (PUFAs) (C18:2, C18:3 and C20:4) PE de PC den daha fazladır. PC nin PUFA içeriği de nispeten yüksektir. C20:4 tavşan dışında rat, insan ve köpek PE nin de göze çarpan bir yağ asididir. Tavşanda ise bunun yerini C18:2 almıştır. MUFA (doymuş yağ asitleri) (C16:1, C18:1, C20:1 and C22:1) yüzdesi de yine PE nde PC den daha fazladır. Bütün türlerde C18:1, C16:1 den daha fazla miktarda bulunmuştur. LCPUFAs (uzun zincirli doymamış yağ asitleri) (C22:4 and C22:6) PE ve PC nde önemli derecede düşüktür. LCPUFA içinde C22:6 yüzdesi insan eritrosit membranmdaki PE de yüksek bulunmuş, köpekte ise bulunmamıştır

Keywords

yağ asitleri RBC membranı PE PC rat tavşan insan köpek

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Details

Primary Language English
Subjects Pharmacology and Pharmaceutical Sciences
Other ID JA89UN93VG
Journal Section Research Article
Authors

Bilgehan Doğru Pekiner This is me

Publication Date September 1, 2002
Submission Date September 1, 2002
Published in Issue Year 2002

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APA Doğru Pekiner, B. (2002). FATTY ACID COMPOSITION OF RED BLOOD CELL MEMBRANE PHOSPHATIDYLETHANOLAMINE AND PHOSPHATIDYLCHOLINE IN RAT, RABBIT, HUMAN AND DOG. Journal of Faculty of Pharmacy of Ankara University, 31(3), 169-182. https://doi.org/10.1501/Eczfak_0000000374
AMA Doğru Pekiner B. FATTY ACID COMPOSITION OF RED BLOOD CELL MEMBRANE PHOSPHATIDYLETHANOLAMINE AND PHOSPHATIDYLCHOLINE IN RAT, RABBIT, HUMAN AND DOG. Ankara Ecz. Fak. Derg. September 2002;31(3):169-182. doi:10.1501/Eczfak_0000000374
Chicago Doğru Pekiner, Bilgehan. “FATTY ACID COMPOSITION OF RED BLOOD CELL MEMBRANE PHOSPHATIDYLETHANOLAMINE AND PHOSPHATIDYLCHOLINE IN RAT, RABBIT, HUMAN AND DOG”. Journal of Faculty of Pharmacy of Ankara University 31, no. 3 (September 2002): 169-82. https://doi.org/10.1501/Eczfak_0000000374.
EndNote Doğru Pekiner B (September 1, 2002) FATTY ACID COMPOSITION OF RED BLOOD CELL MEMBRANE PHOSPHATIDYLETHANOLAMINE AND PHOSPHATIDYLCHOLINE IN RAT, RABBIT, HUMAN AND DOG. Journal of Faculty of Pharmacy of Ankara University 31 3 169–182.
IEEE B. Doğru Pekiner, “FATTY ACID COMPOSITION OF RED BLOOD CELL MEMBRANE PHOSPHATIDYLETHANOLAMINE AND PHOSPHATIDYLCHOLINE IN RAT, RABBIT, HUMAN AND DOG”, Ankara Ecz. Fak. Derg., vol. 31, no. 3, pp. 169–182, 2002, doi: 10.1501/Eczfak_0000000374.
ISNAD Doğru Pekiner, Bilgehan. “FATTY ACID COMPOSITION OF RED BLOOD CELL MEMBRANE PHOSPHATIDYLETHANOLAMINE AND PHOSPHATIDYLCHOLINE IN RAT, RABBIT, HUMAN AND DOG”. Journal of Faculty of Pharmacy of Ankara University 31/3 (September 2002), 169-182. https://doi.org/10.1501/Eczfak_0000000374.
JAMA Doğru Pekiner B. FATTY ACID COMPOSITION OF RED BLOOD CELL MEMBRANE PHOSPHATIDYLETHANOLAMINE AND PHOSPHATIDYLCHOLINE IN RAT, RABBIT, HUMAN AND DOG. Ankara Ecz. Fak. Derg. 2002;31:169–182.
MLA Doğru Pekiner, Bilgehan. “FATTY ACID COMPOSITION OF RED BLOOD CELL MEMBRANE PHOSPHATIDYLETHANOLAMINE AND PHOSPHATIDYLCHOLINE IN RAT, RABBIT, HUMAN AND DOG”. Journal of Faculty of Pharmacy of Ankara University, vol. 31, no. 3, 2002, pp. 169-82, doi:10.1501/Eczfak_0000000374.
Vancouver Doğru Pekiner B. FATTY ACID COMPOSITION OF RED BLOOD CELL MEMBRANE PHOSPHATIDYLETHANOLAMINE AND PHOSPHATIDYLCHOLINE IN RAT, RABBIT, HUMAN AND DOG. Ankara Ecz. Fak. Derg. 2002;31(3):169-82.

Kapsam ve Amaç

Ankara Üniversitesi Eczacılık Fakültesi Dergisi, açık erişim, hakemli bir dergi olup Türkçe veya İngilizce olarak farmasötik bilimler alanındaki önemli gelişmeleri içeren orijinal araştırmalar, derlemeler ve kısa bildiriler için uluslararası bir yayım ortamıdır. Bilimsel toplantılarda sunulan bildiriler supleman özel sayısı olarak dergide yayımlanabilir. Ayrıca, tüm farmasötik alandaki gelecek ve önceki ulusal ve uluslararası bilimsel toplantılar ile sosyal aktiviteleri içerir.