Nitraria Schoberi (Zygophyllaceae) Ekstrelerinin Farmakolojik Aktiviteleri Üzerine Araştırmalar

Abstract

Nitraria schoberi (Zygophyllaceae) yeni biyoaktif maddelere kaynak oluşturma potansiyeli bakımından bitkiler aleminin ümit veren bir üyesidir. Bitkiden üç ayrı fraksiyon izole edilmiş ve yapılan biyolojik aktivite testleri sonucunda bu fraksiyonlardan ikisinin serotonin benzeri aktivite gösterirken diğerinin de vasküler düz kas gevşetici

Pharmacological Activity of The Extracts of Nitraria Schoberi

Abstract

Nitraria schoberi (Zygophyllaceae) is a promising member of the plant kingdom for new bioactive principles. Three fractions, two with serotonin-like activity and one with vascular smooth muscle relaxing activity were isolated from this plant. Cascade superfusion bioassay system with rabbit aorta, coeliac and mesenteric arteries and rat fundus stomach strip were used for the bioassay in order to detect and characterize the pharmacological activity of the fractions. The results indicate that Nitraria schoberi yields some pharmacologically active substances and this report is the first in literature about the pharmacological activity of the plant