The Quantitative Structure-Activity Relationships of AntifungalActive 2- (p-Substituted-Phenyl) Benzoxazole DerivativesAgainst Candida Albicans Using The Combinations of SomeHydrophobic, Electronic And Steric Parameters

Esin Şener; İsmail Yalçın; Seçkin Özden; Tuncel Özden

doi:10.1501/Eczfak_0000000483

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The Quantitative Structure-Activity Relationships of AntifungalActive 2- (p-Substituted-Phenyl) Benzoxazole DerivativesAgainst Candida Albicans Using The Combinations of SomeHydrophobic, Electronic And Steric Parameters

Abstract

The antifungal active 2-(p-substitutcd-phenyl) benzoxazoles against C. albicans were studied in a QSAR (quantitative structureactivity relationships) work using the multiple regression method. Some of the hydrophobic , electronic ( F, R) and steric (MR, MW, Pr ) constants were used as physicochemical parameters. The correlation equations and the best equation obtained from regression analysis were given. As a result of quantitative structure-activity relationships of 2-(p-substituted-phenyl) benzoxazoles for C. albicans, it was found that hydrophobic, electronic or steric parameters were more significant when they were used in combined forms than they were used separately.

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Primary Language

English

Subjects

Pharmacology and Pharmaceutical Sciences

Journal Section

Conference Paper

Authors

Esin Şener This is me

İsmail Yalçın This is me

Seçkin Özden This is me

Tuncel Özden This is me

Publication Date

June 1, 1986

Submission Date

June 1, 1986

Acceptance Date

-

Published in Issue

Year 1986 Volume: 16 Number: 1

DOI

https://doi.org/10.1501/Eczfak_0000000483

IZ

https://izlik.org/JA77LA82FX

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RIS / Bibtex

APA

Şener, E., Yalçın, İ., Özden, S., & Özden, T. (1986). The Quantitative Structure-Activity Relationships of AntifungalActive 2- (p-Substituted-Phenyl) Benzoxazole DerivativesAgainst Candida Albicans Using The Combinations of SomeHydrophobic, Electronic And Steric Parameters. Journal of Faculty of Pharmacy of Ankara University, 16(1), 24-30. https://doi.org/10.1501/Eczfak_0000000483

AMA

1.Şener E, Yalçın İ, Özden S, Özden T. The Quantitative Structure-Activity Relationships of AntifungalActive 2- (p-Substituted-Phenyl) Benzoxazole DerivativesAgainst Candida Albicans Using The Combinations of SomeHydrophobic, Electronic And Steric Parameters. J. Fac. Pharm. Ankara. 1986;16(1):24-30. doi:10.1501/Eczfak_0000000483

Chicago

Şener, Esin, İsmail Yalçın, Seçkin Özden, and Tuncel Özden. 1986. “The Quantitative Structure-Activity Relationships of AntifungalActive 2- (p-Substituted-Phenyl) Benzoxazole DerivativesAgainst Candida Albicans Using The Combinations of SomeHydrophobic, Electronic And Steric Parameters”. Journal of Faculty of Pharmacy of Ankara University 16 (1): 24-30. https://doi.org/10.1501/Eczfak_0000000483.

EndNote

Şener E, Yalçın İ, Özden S, Özden T (June 1, 1986) The Quantitative Structure-Activity Relationships of AntifungalActive 2- (p-Substituted-Phenyl) Benzoxazole DerivativesAgainst Candida Albicans Using The Combinations of SomeHydrophobic, Electronic And Steric Parameters. Journal of Faculty of Pharmacy of Ankara University 16 1 24–30.

IEEE

[1]E. Şener, İ. Yalçın, S. Özden, and T. Özden, “The Quantitative Structure-Activity Relationships of AntifungalActive 2- (p-Substituted-Phenyl) Benzoxazole DerivativesAgainst Candida Albicans Using The Combinations of SomeHydrophobic, Electronic And Steric Parameters”, J. Fac. Pharm. Ankara, vol. 16, no. 1, pp. 24–30, June 1986, doi: 10.1501/Eczfak_0000000483.

ISNAD

Şener, Esin - Yalçın, İsmail - Özden, Seçkin - Özden, Tuncel. “The Quantitative Structure-Activity Relationships of AntifungalActive 2- (p-Substituted-Phenyl) Benzoxazole DerivativesAgainst Candida Albicans Using The Combinations of SomeHydrophobic, Electronic And Steric Parameters”. Journal of Faculty of Pharmacy of Ankara University 16/1 (June 1, 1986): 24-30. https://doi.org/10.1501/Eczfak_0000000483.

JAMA

1.Şener E, Yalçın İ, Özden S, Özden T. The Quantitative Structure-Activity Relationships of AntifungalActive 2- (p-Substituted-Phenyl) Benzoxazole DerivativesAgainst Candida Albicans Using The Combinations of SomeHydrophobic, Electronic And Steric Parameters. J. Fac. Pharm. Ankara. 1986;16:24–30.

MLA

Şener, Esin, et al. “The Quantitative Structure-Activity Relationships of AntifungalActive 2- (p-Substituted-Phenyl) Benzoxazole DerivativesAgainst Candida Albicans Using The Combinations of SomeHydrophobic, Electronic And Steric Parameters”. Journal of Faculty of Pharmacy of Ankara University, vol. 16, no. 1, June 1986, pp. 24-30, doi:10.1501/Eczfak_0000000483.

Vancouver

1.Esin Şener, İsmail Yalçın, Seçkin Özden, Tuncel Özden. The Quantitative Structure-Activity Relationships of AntifungalActive 2- (p-Substituted-Phenyl) Benzoxazole DerivativesAgainst Candida Albicans Using The Combinations of SomeHydrophobic, Electronic And Steric Parameters. J. Fac. Pharm. Ankara. 1986 Jun. 1;16(1):24-30. doi:10.1501/Eczfak_0000000483

The Quantitative Structure-Activity Relationships of AntifungalActive 2- (p-Substituted-Phenyl) Benzoxazole DerivativesAgainst Candida Albicans Using The Combinations of SomeHydrophobic, Electronic And Steric Parameters

The Quantitative Structure-Activity Relationships of AntifungalActive 2- (p-Substituted-Phenyl) Benzoxazole DerivativesAgainst Candida Albicans Using The Combinations of SomeHydrophobic, Electronic And Steric Parameters

Abstract

Keywords

Candida Albicans'a Karşı Antifungal Etkili 2-(p-Sübstitüe-Fenil) Benzoksazol Türevleri ile Bazı Hidrofobik, Elektronik, Sterik Parametreler Kombinasyonlarının Kantitatif Yapı-Etki ilişkileri

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