FATTY ACID COMPOSITION OF RED BLOOD CELL MEMBRANE PHOSPHATIDYLETHANOLAMINE AND PHOSPHATIDYLCHOLINE IN RAT, RABBIT, HUMAN AND DOG

Bilgehan Doğru Pekiner

doi:10.1501/Eczfak_0000000374

Research Article

FATTY ACID COMPOSITION OF RED BLOOD CELL MEMBRANE PHOSPHATIDYLETHANOLAMINE AND PHOSPHATIDYLCHOLINE IN RAT, RABBIT, HUMAN AND DOG

Year 2002, Volume: 31 Issue: 3, 169 - 182, 01.09.2002

Bilgehan Doğru Pekiner

https://doi.org/10.1501/Eczfak_0000000374

Abstract

RBC (red blood cell) membrane fatty acid percentages in PE (phosphatidylethanolamine) and PC (phosphatidylcholine) in different species like rats, rabbits, humans and dogs were measured and compared. The major fatty acids of membrane PE and PC in the species were same as C16:0, C18:1,, C18:1, C18:2and C20:4. SFAs (Saturatedfatty acids) (C16:0, C18:0, and C20:0) were lower in PE but higher in PC in all species in RBC membrane. Arachidonate (C20:4 ) and PUFAs (polyunsaturated fatty acid) (C18:2, C18:3 and C20:4) were higher in PE than PC. PC also had relatively high PUFA content. C20:4 was a prominent fatty acid of PE in rat, human and dog except rabbit. C18:22 was the prominent fatty acid in the rabbit. MUFA (monounsaturated fatty acid) (C16:1,C18:1 C18:1, C20:1 and C22:1) percentage was also higher in PE than PC. C18:1 was found considerably higher than C16:1 in all species. LCPUFAs (long chain polyunsaturated fatty acids) (C22:4, and C22:6 were significantly lower in the species PE and PC. Among LCPUFA, C22:6 was high in human RBC membrane PE and was not detected in dog

Keywords

fatty acids, RBC membrane, PE, PC, rat, rabbit, human, dog

SIÇAN, TAVŞAN, İNSAN VE KÖPEK ERİTROSİT MEMBRANI FOSFATİDİLETANOLAMİN VE FOSFATİDİLKOLİNİN YAĞ ASİDİ KOMPOZİSYONU

Year 2002, Volume: 31 Issue: 3, 169 - 182, 01.09.2002

Bilgehan Doğru Pekiner

https://doi.org/10.1501/Eczfak_0000000374

Abstract

Rat, tavşan, insan ve köpek gibi farklı türlerin kırmızı kan hücreleri fosfatidiletanolamin (PE) ve fosfatidilkolini (PC) yağ asitleri tayin edilmiş ve karşılaştırılmıştır. Türlerin membran PE ve PC yağ asitleri başlıca C16:0, C18:0, C18:1, Q18:2 ve C20:4 dir. Doymuş yağ asitleri (SFA) (C18:0, C18:0, ve C20:0) bütün türlerde PE de düşük ancak PC de yüksek düzeydedir. Arakidonat (C20:4 ) ve çoklu doymamış yağ asitleri (PUFAs) (C18:2, C18:3 and C20:4) PE de PC den daha fazladır. PC nin PUFA içeriği de nispeten yüksektir. C20:4 tavşan dışında rat, insan ve köpek PE nin de göze çarpan bir yağ asididir. Tavşanda ise bunun yerini C18:2 almıştır. MUFA (doymuş yağ asitleri) (C16:1, C18:1, C20:1 and C22:1) yüzdesi de yine PE nde PC den daha fazladır. Bütün türlerde C18:1, C16:1 den daha fazla miktarda bulunmuştur. LCPUFAs (uzun zincirli doymamış yağ asitleri) (C22:4 and C22:6) PE ve PC nde önemli derecede düşüktür. LCPUFA içinde C22:6 yüzdesi insan eritrosit membranmdaki PE de yüksek bulunmuş, köpekte ise bulunmamıştır

Keywords

yağ asitleri, RBC membranı, PE, PC, rat, tavşan, insan, köpek

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Details

Primary Language	English
Subjects	Pharmacology and Pharmaceutical Sciences
Other ID	JA89UN93VG
Journal Section	Research Article
Authors	Bilgehan Doğru Pekiner This is me
Publication Date	September 1, 2002
Submission Date	September 1, 2002
Published in Issue	Year 2002 Volume: 31 Issue: 3

Cite

APA	Doğru Pekiner, B. (2002). FATTY ACID COMPOSITION OF RED BLOOD CELL MEMBRANE PHOSPHATIDYLETHANOLAMINE AND PHOSPHATIDYLCHOLINE IN RAT, RABBIT, HUMAN AND DOG. Journal of Faculty of Pharmacy of Ankara University, 31(3), 169-182. https://doi.org/10.1501/Eczfak_0000000374
AMA	Doğru Pekiner B. FATTY ACID COMPOSITION OF RED BLOOD CELL MEMBRANE PHOSPHATIDYLETHANOLAMINE AND PHOSPHATIDYLCHOLINE IN RAT, RABBIT, HUMAN AND DOG. J. Fac. Pharm. Ankara. September 2002;31(3):169-182. doi:10.1501/Eczfak_0000000374
Chicago	Doğru Pekiner, Bilgehan. “FATTY ACID COMPOSITION OF RED BLOOD CELL MEMBRANE PHOSPHATIDYLETHANOLAMINE AND PHOSPHATIDYLCHOLINE IN RAT, RABBIT, HUMAN AND DOG”. Journal of Faculty of Pharmacy of Ankara University 31, no. 3 (September 2002): 169-82. https://doi.org/10.1501/Eczfak_0000000374.
EndNote	Doğru Pekiner B (September 1, 2002) FATTY ACID COMPOSITION OF RED BLOOD CELL MEMBRANE PHOSPHATIDYLETHANOLAMINE AND PHOSPHATIDYLCHOLINE IN RAT, RABBIT, HUMAN AND DOG. Journal of Faculty of Pharmacy of Ankara University 31 3 169–182.
IEEE	B. Doğru Pekiner, “FATTY ACID COMPOSITION OF RED BLOOD CELL MEMBRANE PHOSPHATIDYLETHANOLAMINE AND PHOSPHATIDYLCHOLINE IN RAT, RABBIT, HUMAN AND DOG”, J. Fac. Pharm. Ankara, vol. 31, no. 3, pp. 169–182, 2002, doi: 10.1501/Eczfak_0000000374.
ISNAD	Doğru Pekiner, Bilgehan. “FATTY ACID COMPOSITION OF RED BLOOD CELL MEMBRANE PHOSPHATIDYLETHANOLAMINE AND PHOSPHATIDYLCHOLINE IN RAT, RABBIT, HUMAN AND DOG”. Journal of Faculty of Pharmacy of Ankara University 31/3 (September 2002), 169-182. https://doi.org/10.1501/Eczfak_0000000374.
JAMA	Doğru Pekiner B. FATTY ACID COMPOSITION OF RED BLOOD CELL MEMBRANE PHOSPHATIDYLETHANOLAMINE AND PHOSPHATIDYLCHOLINE IN RAT, RABBIT, HUMAN AND DOG. J. Fac. Pharm. Ankara. 2002;31:169–182.
MLA	Doğru Pekiner, Bilgehan. “FATTY ACID COMPOSITION OF RED BLOOD CELL MEMBRANE PHOSPHATIDYLETHANOLAMINE AND PHOSPHATIDYLCHOLINE IN RAT, RABBIT, HUMAN AND DOG”. Journal of Faculty of Pharmacy of Ankara University, vol. 31, no. 3, 2002, pp. 169-82, doi:10.1501/Eczfak_0000000374.
Vancouver	Doğru Pekiner B. FATTY ACID COMPOSITION OF RED BLOOD CELL MEMBRANE PHOSPHATIDYLETHANOLAMINE AND PHOSPHATIDYLCHOLINE IN RAT, RABBIT, HUMAN AND DOG. J. Fac. Pharm. Ankara. 2002;31(3):169-82.

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The Journal of Faculty of Pharmacy of Ankara University is an international medium, an open access, peer-reviewed journal for the publication of original research reports, reviews and short communications in English or Turkish on relevant developments in pharmaceutical sciences., Proceeding of scientific meetings may be published as special issues of supplements to the journal. Additionally, it contains previous and forthcoming national and international scientific meetings with social activities in pharmaceutical areas.