(s )-Triazol -N-Glikozitleri.I. "İzoniazit" Izonikotinik Asit Hidrazitinden Hareketle Haz ırlanan 5- (y-piridil )- 1, 2, 4-Triazol-3-Tion'un N-Glikozitleri

Mevlüt Ertan; Rahmiye Ertan

doi:10.1501/Eczfak_0000000228

Conference Paper

N-Glycosides de (s)-Triazoles.I.N-Glycosides de 5-( pyridy1)-1,2,4-Triazole-3-Thion prparepartir de l'Hydrazide de l'Acide Isonicotinique "Isoniazid"

Year 1977, Volume: 7 Issue: 2, 182 - 188, 01.12.1977

Mevlüt Ertan Rahmiye Ertan

https://doi.org/10.1501/Eczfak_0000000228

Abstract

(s )-Triazol -N-Glikozitleri.I. "İzoniazit" Izonikotinik Asit Hidrazitinden Hareketle Haz ırlanan 5- (y-piridil )- 1, 2, 4-Triazol-3-Tion'un N-Glikozitleri

Year 1977, Volume: 7 Issue: 2, 182 - 188, 01.12.1977

Mevlüt Ertan Rahmiye Ertan

https://doi.org/10.1501/Eczfak_0000000228

Abstract

INH (izonikotinilhidrazit= İzoniazit), tüberküloz tedavisinde tartışmasız yeri olan bir maddedir. Üzerinde yap ı lan çalışmalarla sayısız türevi haz ı rlanmıştır (1,2). Bunlardan konumuza ışık tutan bileşikler; glukuronik asit ile yap ılan 1-N-(D-glukurolaktoni1)- izonikotinil hidrazit (3,4) ve 1-N-(2'-asetamino-2'deoksi-D-glukopiranozil)-izonikotinil-hidrazit (5)'lerdir. Bu türevler gerek toksisiteleri ve gerekse aktiviteleri yönünden INH' ı n önemli türevlerini teş kil etmektedirler. INH ve tioüre'den hareketle haz ırlanan 1,2,4-triazol-3-tion (6) türevinin suda çözünür olmamas ı onun tüberküloz tedavisindeki etkisinin kontrolüne olanak vermedi ği için invitro olarak saptanan antiviral etkisi ile tan ı nmıştır (7).

Keywords

Glikozitleri, İzoniazit, Izonikotinik

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Details

Primary Language	Turkish
Subjects	Pharmacology and Pharmaceutical Sciences
Other ID	JA85VE88MG
Journal Section	Research Article
Authors	Mevlüt Ertan This is me Rahmiye Ertan This is me
Publication Date	December 1, 1977
Submission Date	December 1, 1977
Published in Issue	Year 1977 Volume: 7 Issue: 2

Cite

APA	Ertan, M., & Ertan, R. (1977). (s )-Triazol -N-Glikozitleri.I. "İzoniazit" Izonikotinik Asit Hidrazitinden Hareketle Haz ırlanan 5- (y-piridil )- 1, 2, 4-Triazol-3-Tion’un N-Glikozitleri. Journal of Faculty of Pharmacy of Ankara University, 7(2), 182-188. https://doi.org/10.1501/Eczfak_0000000228
AMA	Ertan M, Ertan R. (s )-Triazol -N-Glikozitleri.I. "İzoniazit" Izonikotinik Asit Hidrazitinden Hareketle Haz ırlanan 5- (y-piridil )- 1, 2, 4-Triazol-3-Tion’un N-Glikozitleri. J. Fac. Pharm. Ankara. December 1977;7(2):182-188. doi:10.1501/Eczfak_0000000228
Chicago	Ertan, Mevlüt, and Rahmiye Ertan. “(s )-Triazol -N-Glikozitleri.I. ‘İzoniazit’ Izonikotinik Asit Hidrazitinden Hareketle Haz ırlanan 5- (y-Piridil )- 1, 2, 4-Triazol-3-Tion’un N-Glikozitleri”. Journal of Faculty of Pharmacy of Ankara University 7, no. 2 (December 1977): 182-88. https://doi.org/10.1501/Eczfak_0000000228.
EndNote	Ertan M, Ertan R (December 1, 1977) (s )-Triazol -N-Glikozitleri.I. "İzoniazit" Izonikotinik Asit Hidrazitinden Hareketle Haz ırlanan 5- (y-piridil )- 1, 2, 4-Triazol-3-Tion’un N-Glikozitleri. Journal of Faculty of Pharmacy of Ankara University 7 2 182–188.
IEEE	M. Ertan and R. Ertan, “(s )-Triazol -N-Glikozitleri.I. ‘İzoniazit’ Izonikotinik Asit Hidrazitinden Hareketle Haz ırlanan 5- (y-piridil )- 1, 2, 4-Triazol-3-Tion’un N-Glikozitleri”, J. Fac. Pharm. Ankara, vol. 7, no. 2, pp. 182–188, 1977, doi: 10.1501/Eczfak_0000000228.
ISNAD	Ertan, Mevlüt - Ertan, Rahmiye. “(s )-Triazol -N-Glikozitleri.I. ‘İzoniazit’ Izonikotinik Asit Hidrazitinden Hareketle Haz ırlanan 5- (y-Piridil )- 1, 2, 4-Triazol-3-Tion’un N-Glikozitleri”. Journal of Faculty of Pharmacy of Ankara University 7/2 (December 1977), 182-188. https://doi.org/10.1501/Eczfak_0000000228.
JAMA	Ertan M, Ertan R. (s )-Triazol -N-Glikozitleri.I. "İzoniazit" Izonikotinik Asit Hidrazitinden Hareketle Haz ırlanan 5- (y-piridil )- 1, 2, 4-Triazol-3-Tion’un N-Glikozitleri. J. Fac. Pharm. Ankara. 1977;7:182–188.
MLA	Ertan, Mevlüt and Rahmiye Ertan. “(s )-Triazol -N-Glikozitleri.I. ‘İzoniazit’ Izonikotinik Asit Hidrazitinden Hareketle Haz ırlanan 5- (y-Piridil )- 1, 2, 4-Triazol-3-Tion’un N-Glikozitleri”. Journal of Faculty of Pharmacy of Ankara University, vol. 7, no. 2, 1977, pp. 182-8, doi:10.1501/Eczfak_0000000228.
Vancouver	Ertan M, Ertan R. (s )-Triazol -N-Glikozitleri.I. "İzoniazit" Izonikotinik Asit Hidrazitinden Hareketle Haz ırlanan 5- (y-piridil )- 1, 2, 4-Triazol-3-Tion’un N-Glikozitleri. J. Fac. Pharm. Ankara. 1977;7(2):182-8.

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The Journal of Faculty of Pharmacy of Ankara University is an international medium, an open access, peer-reviewed journal for the publication of original research reports, reviews and short communications in English or Turkish on relevant developments in pharmaceutical sciences., Proceeding of scientific meetings may be published as special issues of supplements to the journal. Additionally, it contains previous and forthcoming national and international scientific meetings with social activities in pharmaceutical areas.