Comparison of the effects of hydroxyethyl starch and succinylated gelatin infusion on the perfusion index in elective caesarean sections under spinal anaesthesia

Year 2022, , 1477 - 1483, 25.09.2022

Erdinç Koca

https://doi.org/10.32322/jhsm.1145979

Abstract

Aim: This study is to compare the alterations of three different replacement fluids on Perfusion Index, Pleth Variability Index (PI, PVI) and hemodynamic data in cases planned to experience caesarean surgery under spinal anaesthesia.
Material and Method: 94 ASAII class patients aged 18–40 that were planned to experience caesarean surgery were included in the study. The patients were divided into three groups according to the fluid replacement to be applied. Patients in Group H received 10 ml/kg of hydroxyethyl starch (HES) up to a maximum of 500 ml over 20 minutes. Patients in Group G got 10 ml/kg of modified liquid gelatin(GEL) up to a maximum of 500 ml over 20 minutes. Patients in Group I got 20 ml/kg of isotonic sodium chloride (0.9% NaCl) over 20 minutes. Routine monitoring and perfusion index, pleth variability index were recorded baseline and at the first, third and tenth min after spinal anaesthesia for all participants
Results: A significant increase in the PI value over time was observed in Groups G and I (p=0.001*). According to the PVI results, the amount of decrease in Group G was statistically less than in the other two groups (p=0.015*).
Conclusion: In conclusion, 0.9% NaCl and gelatine were more effective on PI in caesarean section under spinal anesthesia. Isotonic has a positive effect on both PI and PVI. We detected that PI increased compared to baseline values, and believe that this increase may a positive effect on tissue circulation in the patient.

Keywords

Hydroxyethyl starch, succinylated gelatin, perfusion index

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