The relationship between uric acid albumin ratio (UAR) and prognosis in patients with atrial fibrillation hospitalized in intensive care unit

Year 2024, , 505 - 508, 27.09.2024

Azmi Eyiol , Birsen Ertekin

https://doi.org/10.32322/jhsm.1513638

Abstract

Aims: Recent studies have demonstrated an association between uric acid (UA) albumin ratio (UAR), and newly developing atrial fibrillation (AF) and also AF recurrence. We conducted a study to examine the prognostic value of UAR in critically ill patients with AF.
Methods: A retrospective examination was conducted on patients diagnosed with AF based on electrocardiography, who admitted to the intensive care unit (ICU) from the emergency department during the period from January 1st to May 1st, 2024. UAR levels were calculated by dividing the amount of UA by the amount of albumin. Based on the cut-off value, UAR levels were categorized into two groups: low UAR and high UAR. A comprehensive comparison was conducted on all the data between these two groups.
Results: The high UAR (UAR>0.231) group exhibited significantly higher UA, vasopressor requirement, mechanical ventilation support, length of stay in ICU, and in-hospital mortality rate compared to the low UAR (UAR≤0.231) group. Conversely, albumin levels were significantly lower (p<0.001 for all). The UAR cut-off value was 0.231, with a sensitivity of 97.3% and a specificity of 96.7% (The area under the curve (AUC):0.995, p<0.001). The mortality prediction ability of UAR was superior to that of albumin and UA alone (AUC: 0.995, 0.956, 0.981, respectively).
Conclusion: UAR is a cost-effective, easily accessible, useful marker for assessing the prognosis of critically ill patients with AF in ICU.

Keywords

Uric acid albumin ratio, atrial fibrillation, intensive care unit, prognosis, mortality

Ethical Statement

The study was initiated with the approval of the Necmettin Erbakan University Medical Faculty Clinical Researches Ethics Committee (Date: 28/06/2024, Decision No:2024/5038[ID:19894]).

Supporting Institution

Yoktur

Thanks

yoktur

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