Biosurgery: utility in chronic wound

Year 2018, , 19 - 21, 05.04.2018

Ali Korhan Sığ

https://doi.org/10.32322/jhsm.396256

Abstract

Biosurgery
or maggot debridement therapy or larval therapy is a complementary –
integrative medicinal method that it has proven utilities especially in chronic
wound care. The method nearly provides every activity desired from a wound
care. Its modes of action can be divided into four major titles; i) Mechanic debridement,
ii) Antimicrobial action, iii) Directing the tissue to wound healing, iv)
Biofilm degradation. Furthermore, many isolated proteins from maggots showing
various activities give a potential for future drugs. For now, whole effect
mechanisms remain unclear and this therapy is not used as a single treatment
method; it is actually a part of multidisciplinary approach to wound care.

Keywords

Lucilia sericata, chronic wound care, larval debridement, maggot debridement therapy

Biyocerrahi: kronik yara bakımındaki yeri

Abstract

Biyocerrahi
veya maggot debritman tedavisi veya larval terapi faydası özellikle kronik yara
bakımında kanıtlanmış bir tamamlayıcı tıp uygulamasıdır. Uygulama neredeyse
kronik yara bakımından istenen tüm nitelikleri taşımaktadır. Etki mekanizması
temelde dört bölümde incelenebilir; i) Mekanik debritman, ii) Antimikrobiyal
etki, iii) Yara iyileşmesini uyarma, iv) Biyofilm yıkımı. Maggotlardan izole
edilen çok sayıda protein yeni ilaçların üretilmesinde ciddi potansiyel
taşımaktadır. Şu an için, bu uygulamanın etki mekanizmaları tamamen
aydınlatılamamıştır ve uygulama salt bir tedavi yöntemi olarak
değerlendirilmemekte; aslen, kronik yara bakımına çok disiplinli bir yaklaşımın
parçası olarak sunulmaktadır.

Keywords

Lucilia sericata, kronik yara .bakımı, larva terapi, maggot debritman tedavisi

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