Relationship between glycosylated hemoglobin and plateletcrit of type 2 diabetes patients

Year 2019, , 40 - 43, 01.04.2019

Murat Doğan , İrfan Karahan

https://doi.org/10.32322/jhsm.486180

Abstract

Aim: Type
2 diabetes can cause serious vascular problems. Abnormal plateletcrit (PCT)
levels were shown as a risc factor for coronary artery diseases by recent
studies. Glycosylated hemoglonin (HbA1c) is widely ysed marker for assessment
of glycemic control. This study aimed to evaluate relationship between HbA1c
and PCT.

Material and Method:
It is retrospective case control study. 65 type 2 diabetic patients’ records
were evaluated. Correlation between HbA1c and PCT, MPV was investigated.

Results:
Between HbA1c and PCT levels, statistically significant correlation was
detected (r=0,4 p<0,01). Any correlation wasn’t detected with MPV.

Conclusion: Plateletcrit
may be guide for preventing vascular complication due to poor glycemic
regulation. Therefore patients with increased plateletcrit values, should be
evaluated for higher risk of vascular complications.

Keywords

HbA1c, glycemic control, plataletcrit, type 2 diabetes

Tip 2 diyabet hastalarında glikolize hemoglobin ve plataletcrit ilişkisi

Abstract

Amaç:
Tip 2 diyabet ciddi damar hastalıklarına yol açabilen bir hastalıktır.
Plateletcrit (PCT) anormal düzeyleri yapılan çalışmalarda koroner arter
hastalıkları için risk faktörü olarak belirlenmiştir. Glikolize hemoglobin
(HbA1c), glisemik kontrolü değerlendirmek için geniş kullanıma sahip bir
belirteçtir. Bu çalışmada PCT ile HbA1c arasındaki ilişkinin değerlendirilmesi
amaçlanmıştır.

Gereç ve yöntem: Çalışma,
retrospektif vaka kontrol çalışmasıdır. Tip 2 diyabetli 65 hastanın geçmiş
kayıtları değerlendirilmiş,HbA1c ve MPV, PCT arasındaki ilişki araştırılmıştır.

Bulgular:
HbA1c ve PCT arasında anlamlı korelasyon saptandı (r=0,4 p<0,01). MPV ile
korelasyon saptanmadı.

Sonuç:
PCT, glisemik kontrolü sağlanmayan ve buna bağlı vasküler hasar gelişme
olasılığı olan hastalarda yol gösterici olabilir. Bu açıdan, anormal PCT
düzeyleri olan hastaların vasküler patolojiler açısından yakın takibi önemli
olabilir.

Keywords

HbA1c, plataletcrit, glisemik kontrol, tip 2 diyabet

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