Giriş ve Amaç: Konjenital enfeksiyonlar ölü doğum ve perinatal
morbiditenin önemli bir sebebidir. Antenatal tarama testleri yapılması
kararının verilmesinde bölgesel seropozitiflik oranlarının bilinmesi önemidir.
Bu nedenle doğurganlık çağındaki kadınlarda toksoplazma, rubella ve sitomegalovirüs
(CMV) seropozifliğinin araştırılması amaçlanmıştır.
Gereç ve Yöntem: 1
Ocak 2017 ile 1 Ocak 2018 tarihleri arasında, Yozgat Şehir Hastanesi Mikrobiyoloji
Laboratuvarı’nda çalışılan toksoplazma, rubella ve CMV antikorları retrospektif
olarak taranmıştır. Çalışmaya, 15-47 yaş arası kadınlar dahil edilmiştir. 2447
kadının toksoplazma, 2612 kadının rubella ve 873 kadının CMV seroloji sonuçları
ve yaşları SPSS 15.0 istatistik paket programına kaydedilmiştir
Bulgular: Çalışmamızda, toksoplazma IgM %0, toksoplazma IgG %27, rubella
IgM %1,3, rubella IgG %92, CMV IgM %1,1, CMV IgG %99 oranında pozitif
saptanmıştır. Toksoplazma IgG pozitif olan grubun yaş ortalaması 30±5,9 iken,
IgG negatif olan grupta 27,7±5,6 olduğu görülmüş ve bu fark istatistiksel
olarak anlamlı saptanmıştır (p:0.00).
Sonuç: Toksoplazma için
sadece risk grubunda olan, enfeksiyondan şüphelenilen, immunsuprese veya HIV
pozitif bireylere prenatal tarama yapılmasının,
gebe ve gebelik planı olan kadınlara eğitim verilmesinin ve akut enfeksiyon
durumunda tedavi planlanmasının uygun olacağını düşünmekteyiz. Rubella için taramaların yapılması ve seronegatif
kadınlara gebelik öncesi veya gebelikten sonra aşı yapılması önerilmelidir.
Fakat CMV seropozitifliğinin yüksek olması nedeniyle sadece bulaş için risk
grubunda olan kadınlara tarama yapılması ve konjenital CMV enfeksiyonu ve
korunma önlemleri ile ilgili eğitim verilmesi uygun olacaktır.
Introduction/Aim: Congenital infections are an important cause of stillbirth
and perinatal morbidity. It is important to know the regional seropositivity
rates when making the decision to conduct antenatal screening tests. Therefore,
in this study, it is aimed to investigate the seropositivity of toxoplasma, rubella, and cytomegalovirus (CMV) in women of childbearing age. Material and Methods: During the period of January–2017 and January–2018,
Toxoplasma, Rubella, and CMV antibodies in Yozgat City Hospital microbiology
laboratory were retrospectively screened. Women between 15 and 47 years of age
were included in the study. Of them, for 2447 women, the results of
toxoplasmosis, for 2612 women of rubella and for 873 women of CMV serology and
their age were recorded in SPSS 15.0 statistical package program. Findings/Results: In our study, Toxoplasma IgM 0%, Toxoplasma IgG 27%,
Rubella IgM 1.3%, Rubella IgG 92%, CMV IgM 1.1%, CMV IgG 99% were found to be
positive. The mean age of the Toxoplasma IgG positive group was 30 ± 5.9, while
it was 27.7 ± 5.6 in the IgG negative group and this difference was
statistically significant (p: 0.00). Conclusion: We think that prenatal screening for Toxoplasma,
training of seronegative individuals and the treatment planning in case of
acute infection are important. It is recommended that screening for Rubella and
vaccination of seronegative women be given before or after pregnancy. However,
due to high CMV seropositivity it may be appropriate to screen only women at a
risk for transmission and to provide training in congenital CMV infection and
prevention measures.
Primary Language | English |
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Subjects | Health Care Administration |
Journal Section | Original Article |
Authors | |
Publication Date | January 15, 2020 |
Published in Issue | Year 2020 Volume: 3 Issue: 1 |
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Editor List for 2022
Assoc. Prof. Alpaslan TANOĞLU (MD)
Prof. Aydın ÇİFCİ (MD)
Prof. İbrahim Celalaettin HAZNEDAROĞLU (MD)
Prof. Murat KEKİLLİ (MD)
Prof. Yavuz BEYAZIT (MD)
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Assoc. Prof. Mehmet Sinan DAL (MD)
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