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Nadir bir olgu: Jackhammer özofagus

Year 2020, Volume: 3 Issue: 3, 352 - 354, 18.06.2020
https://doi.org/10.32322/jhsm.689035

Abstract

Jackhammer özofagus, özofagus manometri incelemelerinin ortalama %4’ünde saptanan peristaltik hiperkontraktil motilite bozukluğudur. Tanısı çoğunlukla disfaji, bazen göğüs ağrısı veya gastroözofageal reflü şikayetleri ile başvuran hastalarda konur. Disfaji semptomu, alt özofageal sfinkterdeki güçlü kasılmalar, özofageal çıkış darlığı ve yüksek distal kontraktil integral ile ilişkilidir. Jackhammer özofagus tedavisi ile ilgili net bir konsensüs bulunmamaktadır. Asid maruziyetinin azaltılması semptom ve motor bozukluğunu azalttığı gösterilmiştir. Ağırlıklı semptomlar göğüs ağrısı ve disfaji için ise nöromodülatörler ile düz kas gevşeticileri verilebilir. Ağır refrakter olgularda özofageal Botulinum toksini enjeksiyonu ve POEM gibi endoskopik yöntemlerin yanında Heller myotomi gibi cerrahi seçenekler de düşünülebilir. Vakamızda Botulinum enjeksiyonu ve kalsiyum kanal blokeri ile klinik yanıt elde edilmiştir.

References

  • 1. Jia Y, Arenas J, Hejazi RA, Elhanafi S, Saadi M, McCallum RW. Frequency of Jackhammer esophagus as the extreme phenotypes of esophageal hypercontractility based on the New Chicago Classification. J Clin Gastroenterol 2016; 50: 615-8.
  • 2. Jia Y, McCallum RW. Jackhammer esophagus based on the New Chicago Classification. J Clin Gastroenterol 2017; 51: 88.
  • 3. Kristo I, Schwameis K, Maschke S, et al. Phenotypes of Jackhammer esophagus in patients with typical symptoms of gastroesophageal reflux disease responsive to proton pump inhibitors. Sci Rep 2018; 8: 9949.
  • 4. Roman S, Kahrilas PJ. Management of spastic disorders of the esophagus. Gastroenterol Clin North Am 2013; 42: 27-43.
  • 5. Marjoux S, Brochard C, Roman S, et al. Botulinum toxin injection for hypercontractile or spastic esophageal motility disorders: may high-resolution manometry help to select cases? Dis Esophagus 2015; 28: 735-41.
  • 6. Khan MA, Kumbhari V, Ngamruengphong S, et al. Is POEM the answer for management of spastic esophageal disorders? A Systematic Review and Meta-Analysis. Dig Dis Sci 2017; 62: 35-44.

A rare case: Jackhammer esophagus

Year 2020, Volume: 3 Issue: 3, 352 - 354, 18.06.2020
https://doi.org/10.32322/jhsm.689035

Abstract

Jackhammer esophagus is a peristaltic hypercontractile motility disorder detected on average of 4% of esophageal manometry examinations. The diagnosis is mostly performed in patients presenting with dysphagia, sometimes chest pain or gastroesophageal reflux. The symptom of dysphagia is associated with strong contractions in the lower esophageal sphincter, esophageal outlet stenosis, and high distal contractile integral. There is no clear consensus regarding Jackhammer esophageal therapy. Reducing acid exposure has been shown to reduce symptoms and motor impairment. If the main symptoms are chest pain and dysphagia, neuromodulators and smooth muscle relaxants can be given. In severe refractory cases, besides endoscopic methods such as esophageal Botulinum toxin injection and POEM, surgical options such as Heller myotomy can be considered. In our case, clinical response was obtained with Botulinum injection and calcium channel blocker.

References

  • 1. Jia Y, Arenas J, Hejazi RA, Elhanafi S, Saadi M, McCallum RW. Frequency of Jackhammer esophagus as the extreme phenotypes of esophageal hypercontractility based on the New Chicago Classification. J Clin Gastroenterol 2016; 50: 615-8.
  • 2. Jia Y, McCallum RW. Jackhammer esophagus based on the New Chicago Classification. J Clin Gastroenterol 2017; 51: 88.
  • 3. Kristo I, Schwameis K, Maschke S, et al. Phenotypes of Jackhammer esophagus in patients with typical symptoms of gastroesophageal reflux disease responsive to proton pump inhibitors. Sci Rep 2018; 8: 9949.
  • 4. Roman S, Kahrilas PJ. Management of spastic disorders of the esophagus. Gastroenterol Clin North Am 2013; 42: 27-43.
  • 5. Marjoux S, Brochard C, Roman S, et al. Botulinum toxin injection for hypercontractile or spastic esophageal motility disorders: may high-resolution manometry help to select cases? Dis Esophagus 2015; 28: 735-41.
  • 6. Khan MA, Kumbhari V, Ngamruengphong S, et al. Is POEM the answer for management of spastic esophageal disorders? A Systematic Review and Meta-Analysis. Dig Dis Sci 2017; 62: 35-44.
There are 6 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Case Report
Authors

Müjgan Gürler 0000-0001-8777-9077

Murat Pehlivan 0000-0001-5427-2122

Güray Can 0000-0002-6054-9244

Meral Akdoğan Kayhan 0000-0001-6885-6911

Publication Date June 18, 2020
Published in Issue Year 2020 Volume: 3 Issue: 3

Cite

AMA Gürler M, Pehlivan M, Can G, Akdoğan Kayhan M. Nadir bir olgu: Jackhammer özofagus. J Health Sci Med / JHSM. June 2020;3(3):352-354. doi:10.32322/jhsm.689035

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