Prognostic value of blood gas lactate levels among COVID-19 patients who visited to emergency department

Year 2021, Volume: 4 Issue: 4, 493 - 497, 15.07.2021

Erdem Kurt , Suphi Bahadırlı

https://doi.org/10.32322/jhsm.934484

Abstract

Objective: Our aim in this study, to determine the relationship between the mortality status and the ICU requirement of COVID-19 patients, with their blood gas lactate levels at the time of admission to the ED.
Material and method: This study was planned as retrospectively, all COVID-19 patients over the age of 18 who were admitted to the ED, had oropharyngeal /nasopharyngeal swabs and hospitalized between April 1, 2020 and June 31, 2020 were included. The primary outcome was in-hospital mortality. The secondary outcome is to determine the relationship between lactate levels and the ICU requirement
Results: The study was completed with 265 patients after the inclusion and exclusion criteria were applied. The median (IQR) age of the patients was 43.0 (31.0 – 59.0), and 132 (49.8%) were female. The comorbid diseases are; hypertension (HT), cardiovascular disease and diabetes mellitus (DM) were in the first three places with 23.0%, 17.0%, 9.1%, respectively. The cut-off value of lactate to determined for ICU admissions was 2.92, and 4.25 for mortality.The AUC for ICU requirement was 0.718 ± 0.038 (95% CI, 0.644 - 0.792), and AUC for mortality was 0.752 ± 0.058 (95% CI, 0.637 - 0.867), (p <0.001 for both).
Conclusions: The COVID-19 pandemic has caused a serious mortality and morbidity problem worldwide. Our study found that hyperlactatemic COVID-19 patients had higher ICU requirement and mortality rates.

Keywords

covid-19, lactate, prognostic, mortality

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