Research Article
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Year 2021, Volume 4, Issue 6, 960 - 966, 24.09.2021
https://doi.org/10.32322/jhsm.991465

Abstract

References

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  • Liu K, Chen Y, Lin R, Han K. Clinical features of COVID-19 in elderly patients: A comparison with young and middle-aged patients. J Infect 2020; 80: e14-e8.
  • Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet 2020; 395(10223): 507-13.
  • Wang L, He W, Yu X, et al. Coronavirus disease 2019 in elderly patients: Characteristics and prognostic factors based on 4-week follow-up. J Infect 2020; 80: 639-45.
  • Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention. JAMA 2020.
  • Zhu C, He G, Yin Q, et al. Molecular biology of the SARs-CoV-2 spike protein: A review of current knowledge. J Med Virol 2021; 93: 5729-41.
  • Ozcelik F, Tanoglu A, Guven BB, Keskin U, Kaplan M. Assessment of severity and mortality of COVID-19 with anti-A1 and anti-B IgM isohaemagglutinins, a reflection of the innate immune status. Int J Clin Pract 2021: e14624.
  • Beyazit F, Beyazit Y, Tanoglu A, Haznedaroglu IC. Ankaferd hemostat (ABS) as a potential mucosal topical agent for the management of COVID-19 syndrome based on its PAR-1 inhibitory effect and oestrogen content. Med Hypotheses 2020; 143: 110150.
  • Van Eck NJ, & Waltman, L. Text mining and visualization using VOSviewer. ISSI Newsletter 2011; 7: 50-4.
  • Viruses CSGotICoTo. The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2. Nat Microbiol 2020; 5: 536-44.
  • Alshammary AF, Al-Sulaiman AM. The journey of SARS-CoV-2 in human hosts: a review of immune responses, immunosuppression, and their consequences. Virulence 2021; 12: 1771-94.
  • James N, Menzies M. Trends in COVID-19 prevalence and mortality: A year in review. Physica D 2021; 425: 132968.
  • Letko M, Marzi A, Munster V. Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses. Nat Microbiol 2020; 5: 562-9.
  • Li LL, Wang JL, Ma XH, et al. A novel SARS-CoV-2 related coronavirus with complex recombination isolated from bats in Yunnan province, China. Emerg Microbes Infect 2021; 10: 1683-90.
  • Tianyu Z, Liying G. Identifying the molecular targets and mechanisms of xuebijing injection for the treatment of COVID-19 via network parmacology and molecular docking. Bioengineered 2021; 12: 2274-87.
  • Land WG. Role of DAMPs in respiratory virus-induced acute respiratory distress syndrome-with a preliminary reference to SARS-CoV-2 pneumonia. Genes Immun 2021; 22: 141-60.
  • Zhang Z, Liu Q, Sun Y, et al. Live attenuated coronavirus vaccines deficient in N7-Methyltransferase activity induce both humoral and cellular immune responses in mice. Emerg Microbes Infect 2021; 10: 1626-37.
  • de Jesus SF, Santos LI, Rodrigues Neto JF, Vieira TM, Mendes JB, D'angelo MFSV, et al. Therapeutic perceptions in antisense RNA-mediated gene regulation for COVID-19. Gene 2021; 800: 145839.
  • Badua CLDC, Baldo KAT, Medina PMB. Genomic and proteomic mutation landscapes of SARS-CoV-2. J Med Virol 2021; 93: 1702-21.
  • Al-Jaf SMA, Niranji SS, Mahmood ZH. Rapid, inexpensive methods for exploring SARS CoV-2 D614G mutation. Meta Gene 2021; 30: 100950.
  • Sopp NM, Sharda V. An Eye on COVID-19: A Meta-analysis of Positive Conjunctival Reverse Transcriptase-Polymerase Chain Reaction and SARS-CoV-2 Conjunctivitis Prevalence. Optom Vis Sci 2021; 98: 429-36.
  • Tanoğlu EG. Production and distribution of mRNA vaccines: SARS-CoV-2 experience. J Mol Virol Immunol 2020; 1: 27-34.

Evaluation of studies on molecular biology and genetics related to COVID-19 with data mining

Year 2021, Volume 4, Issue 6, 960 - 966, 24.09.2021
https://doi.org/10.32322/jhsm.991465

Abstract

Aim: The aim of this study was to examine the most common studies about molecular biology and genetics related to COVID-19. In addition, the aim was also to determine the subject focus of studies about COVID-19 during the pandemic with data mining. Material and Method: Review and research articles, book chapters, conference abstracts, case reports and mini reviews published between March 2020 and July 2021 were included in this study. We retrieved only articles from the genetics discipline. The MeSH heading “genetics [GENET]” was used including the specific fields in the MeSH hierarchy of cytogenetics, genomics, human genetics, immunogenetics, molecular biology, pharmacogenetics, phenomics, radiation genetics, toxicogenetics, gene ontology, microbial genetics, behavioral and population genetics. Results: A total of 6234 research articles were evaluated in our study. Of the 85966 terms, 5833 met the threshold from title and abstract extraction. We showed that betacoronavirus, viral pneumonia, viral RNA, spike glycoprotein, coronavirus, middle-aged and animals were the most repetitive terms. Clinical laboratory techniques, polymerase chain reaction and reverse transcriptase polymerase techniques were the main focus for the detection of COVID-19. We found that molecular-based COVID-19 studies were most frequently published by the Journal of Medical Virology, Viruses, and PLoS One. We found that the institutes where molecular-based studies investigating COVID-19 were conducted are in the United States (USA), China and England. The USA and China were in the first rank for countries that conducted the most frequent molecular-based COVID-19 studies, and Turkey was in 19th place in terms of published molecular COVID-19 studies. Conclusion: It is important to identify the issues and mechanisms most frequently investigated in molecular-based studies related to COVID-19. Scientific approaches founded on evidence-based data may be beneficial to find the curative treatment for COVID-19 infection and to effectively prevent this infection.

References

  • Jamsheela O. A Study of the correlation between the dates of the first covid case and the first Covid death of 25 selected countries to know the virulence of the Covid-19 in different tropical conditions. Ethics Med Public Health 2021; 19: 100707.
  • Liu K, Chen Y, Lin R, Han K. Clinical features of COVID-19 in elderly patients: A comparison with young and middle-aged patients. J Infect 2020; 80: e14-e8.
  • Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet 2020; 395(10223): 507-13.
  • Wang L, He W, Yu X, et al. Coronavirus disease 2019 in elderly patients: Characteristics and prognostic factors based on 4-week follow-up. J Infect 2020; 80: 639-45.
  • Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention. JAMA 2020.
  • Zhu C, He G, Yin Q, et al. Molecular biology of the SARs-CoV-2 spike protein: A review of current knowledge. J Med Virol 2021; 93: 5729-41.
  • Ozcelik F, Tanoglu A, Guven BB, Keskin U, Kaplan M. Assessment of severity and mortality of COVID-19 with anti-A1 and anti-B IgM isohaemagglutinins, a reflection of the innate immune status. Int J Clin Pract 2021: e14624.
  • Beyazit F, Beyazit Y, Tanoglu A, Haznedaroglu IC. Ankaferd hemostat (ABS) as a potential mucosal topical agent for the management of COVID-19 syndrome based on its PAR-1 inhibitory effect and oestrogen content. Med Hypotheses 2020; 143: 110150.
  • Van Eck NJ, & Waltman, L. Text mining and visualization using VOSviewer. ISSI Newsletter 2011; 7: 50-4.
  • Viruses CSGotICoTo. The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2. Nat Microbiol 2020; 5: 536-44.
  • Alshammary AF, Al-Sulaiman AM. The journey of SARS-CoV-2 in human hosts: a review of immune responses, immunosuppression, and their consequences. Virulence 2021; 12: 1771-94.
  • James N, Menzies M. Trends in COVID-19 prevalence and mortality: A year in review. Physica D 2021; 425: 132968.
  • Letko M, Marzi A, Munster V. Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses. Nat Microbiol 2020; 5: 562-9.
  • Li LL, Wang JL, Ma XH, et al. A novel SARS-CoV-2 related coronavirus with complex recombination isolated from bats in Yunnan province, China. Emerg Microbes Infect 2021; 10: 1683-90.
  • Tianyu Z, Liying G. Identifying the molecular targets and mechanisms of xuebijing injection for the treatment of COVID-19 via network parmacology and molecular docking. Bioengineered 2021; 12: 2274-87.
  • Land WG. Role of DAMPs in respiratory virus-induced acute respiratory distress syndrome-with a preliminary reference to SARS-CoV-2 pneumonia. Genes Immun 2021; 22: 141-60.
  • Zhang Z, Liu Q, Sun Y, et al. Live attenuated coronavirus vaccines deficient in N7-Methyltransferase activity induce both humoral and cellular immune responses in mice. Emerg Microbes Infect 2021; 10: 1626-37.
  • de Jesus SF, Santos LI, Rodrigues Neto JF, Vieira TM, Mendes JB, D'angelo MFSV, et al. Therapeutic perceptions in antisense RNA-mediated gene regulation for COVID-19. Gene 2021; 800: 145839.
  • Badua CLDC, Baldo KAT, Medina PMB. Genomic and proteomic mutation landscapes of SARS-CoV-2. J Med Virol 2021; 93: 1702-21.
  • Al-Jaf SMA, Niranji SS, Mahmood ZH. Rapid, inexpensive methods for exploring SARS CoV-2 D614G mutation. Meta Gene 2021; 30: 100950.
  • Sopp NM, Sharda V. An Eye on COVID-19: A Meta-analysis of Positive Conjunctival Reverse Transcriptase-Polymerase Chain Reaction and SARS-CoV-2 Conjunctivitis Prevalence. Optom Vis Sci 2021; 98: 429-36.
  • Tanoğlu EG. Production and distribution of mRNA vaccines: SARS-CoV-2 experience. J Mol Virol Immunol 2020; 1: 27-34.

Details

Primary Language English
Subjects Health Care Sciences and Services
Journal Section Original Article
Authors

Esra GÜZEL TANOĞLU> (Primary Author)
University of Health Sciences
0000-0002-0909-8935
Türkiye


M.fevzi ESEN>
SAĞLIK BİLİMLERİ ÜNİVERSİTESİ
0000-0001-7823-0883
Türkiye

Publication Date September 24, 2021
Published in Issue Year 2021, Volume 4, Issue 6

Cite

Bibtex @research article { jhsm991465, journal = {Journal of Health Sciences and Medicine}, eissn = {2636-8579}, address = {Kırıkkale Üniversitesi Tıp Fakültesi / İç Hastalıkları Anabilim Dalı}, publisher = {MediHealth Academy Yayıncılık}, year = {2021}, volume = {4}, number = {6}, pages = {960 - 966}, doi = {10.32322/jhsm.991465}, title = {Evaluation of studies on molecular biology and genetics related to COVID-19 with data mining}, key = {cite}, author = {Güzel Tanoğlu, Esra and Esen, M.fevzi} }
APA Güzel Tanoğlu, E. & Esen, M. (2021). Evaluation of studies on molecular biology and genetics related to COVID-19 with data mining . Journal of Health Sciences and Medicine , 4 (6) , 960-966 . DOI: 10.32322/jhsm.991465
MLA Güzel Tanoğlu, E. , Esen, M. "Evaluation of studies on molecular biology and genetics related to COVID-19 with data mining" . Journal of Health Sciences and Medicine 4 (2021 ): 960-966 <https://dergipark.org.tr/en/pub/jhsm/issue/64996/991465>
Chicago Güzel Tanoğlu, E. , Esen, M. "Evaluation of studies on molecular biology and genetics related to COVID-19 with data mining". Journal of Health Sciences and Medicine 4 (2021 ): 960-966
RIS TY - JOUR T1 - Evaluation of studies on molecular biology and genetics related to COVID-19 with data mining AU - Esra Güzel Tanoğlu , M.fevzi Esen Y1 - 2021 PY - 2021 N1 - doi: 10.32322/jhsm.991465 DO - 10.32322/jhsm.991465 T2 - Journal of Health Sciences and Medicine JF - Journal JO - JOR SP - 960 EP - 966 VL - 4 IS - 6 SN - -2636-8579 M3 - doi: 10.32322/jhsm.991465 UR - https://doi.org/10.32322/jhsm.991465 Y2 - 2021 ER -
EndNote %0 Journal of Health Sciences and Medicine Evaluation of studies on molecular biology and genetics related to COVID-19 with data mining %A Esra Güzel Tanoğlu , M.fevzi Esen %T Evaluation of studies on molecular biology and genetics related to COVID-19 with data mining %D 2021 %J Journal of Health Sciences and Medicine %P -2636-8579 %V 4 %N 6 %R doi: 10.32322/jhsm.991465 %U 10.32322/jhsm.991465
ISNAD Güzel Tanoğlu, Esra , Esen, M.fevzi . "Evaluation of studies on molecular biology and genetics related to COVID-19 with data mining". Journal of Health Sciences and Medicine 4 / 6 (September 2021): 960-966 . https://doi.org/10.32322/jhsm.991465
AMA Güzel Tanoğlu E. , Esen M. Evaluation of studies on molecular biology and genetics related to COVID-19 with data mining. J Health Sci Med / JHSM. 2021; 4(6): 960-966.
Vancouver Güzel Tanoğlu E. , Esen M. Evaluation of studies on molecular biology and genetics related to COVID-19 with data mining. Journal of Health Sciences and Medicine. 2021; 4(6): 960-966.
IEEE E. Güzel Tanoğlu and M. Esen , "Evaluation of studies on molecular biology and genetics related to COVID-19 with data mining", Journal of Health Sciences and Medicine, vol. 4, no. 6, pp. 960-966, Sep. 2021, doi:10.32322/jhsm.991465

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