Association of IgE elevation with blood group in COVID-19 patients

Year 2022, Volume: 5 Issue: 4, 1092 - 1096, 20.07.2022

Feray Ferda Şenol , İlkay Bahçeci , Altay Babacan , Sermin Algül

https://doi.org/10.32322/jhsm.1109355

Abstract

Aim : All parameters that are thought to be efficient in getting sick and follow-up of the disease should be investigated because of COVID-19 disease has serious consequences. The aim of this study was to investigate whether there is a relationship between the AB0 blood group with Rh factor systems and the frequency of catching COVID-19 infection and between IgE elevation according to blood groups and COVID-19 positivity.
Material and Method: Blood groups and IgE levels of the control group (2690 patients) were compared retrospectively with 7300 patients who were admitted to our hospital between March 10, 2020, and March 31, 2021, and confirmed as COVID-19 positive with viral ribonucleic acid reverse transcriptase-polymerase chain reaction (RT-PCR).
Results: It was found that among the blood groups, the highest COVID-19 positivity belonged to the A blood group (46.17%) and the lowest belonged to the AB blood group (9.04%). The increase in IgE elevation was found statistically significant in COVID-19 positive patients (P<0.001) when compared to the control group(P<0.001). All blood groups, except AB Rh (-), had a statistically significant increase in IgE level when blood groups were evaluated together with Rh factors (P<0.001).
AB Rh (-) blood group had an increase in IgE level that is not statistically significant (P=0.171).
Conclusion: The results of this study showed that the risk of COVID -19 disease may be associated with the AB0 blood group and Rh factor systems, and high IgE level may be observed in patients during the disease. Therefore, investigation of IgE levels may be beneficial in the follow-up of COVID-19 patients

Keywords

COVID-19, blood group, IgE

Supporting Institution

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Project Number

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Thanks

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