Research Article
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Year 2023, Volume: 6 Issue: 1, 178 - 182, 12.01.2023
https://doi.org/10.32322/jhsm.1216358

Abstract

References

  • Choi N, Edginton HD, Griffin CE, Angus JC. Comparison of two ear cytological collection techniques in dogs with otitis externa. Veterinary Dermatol 2018; 29: 413-e136.
  • Duvignaud A, Lhomme E, Pistone T, et al. Home Treatment of Older People with Symptomatic SARS-CoV-2 Infection (COVID-19): A structured Summary of a Study Protocol for a Multi-Arm Multi-Stage (MAMS) randomized trial to evaluate the efficacy and tolerability of several experimental treatments to reduce the risk of hospitalisation or death in outpatients aged 65 years or older (COVERAGE trial). Trials 2020; 21: 846.
  • Hirsch A, Katz MA, Laufer Peretz A, et al. Study of Healthcare Personnel with Influenza and other Respiratory Viruses in Israel (SHIRI): study protocol. BMC Infect Dis 2018; 18: 550.
  • McDaniel T, Wilson DK, Coulon MS, Sweeney AM, Van Horn ML. Interaction of neighborhood and genetic risk on waist circumference in African-American adults: a longitudinal study. Ann Behav Med 2021; 55: 708-19.
  • Maignan M, Viglino D, Hablot M, et al. Diagnostic accuracy of a rapid RT-PCR assay for point-of-care detection of influenza A/B virus at emergency department admission: A prospective evaluation during the 2017/2018 influenza season. PloS one 2019; 14: e0216308.
  • McIlwain DR, Chen H, Apkarian M, et al. Performance of BioFire array or QuickVue influenza A + B test versus a validation qPCR assay for detection of influenza A during a volunteer A/California/2009/H1N1 challenge study. Virol J 2021; 18: 45.
  • Marshall HS, McMillan M, Koehler A, et al. B Part of It School Leaver protocol: an observational repeat cross-sectional study to assess the impact of a meningococcal serogroup B (4CMenB) vaccine programme on carriage of Neisseria meningitidis. BMJ Open 2019; 9: e027233.
  • Abadoğlu O, Mungan D, Paşaoglu G, Celík G, Misirligil Z. Influenza vaccination in patients with asthma: effect on the frequency of upper respiratory tract infections and exacerbations. J Asthma 2004; 41: 279-83.
  • Anar C, Bicmen C, Yapicioglu S, Unsal I, Halilcolar H, Yilmaz U. Evaluation of clinical data and antibody response following influenza vaccination in patients with chronic obstructive pulmonary disease. New Microbiologica 2010; 33: 117-27.
  • Benson ER, Alphin RL, Rankin MK, Caputo MP, Hougentogler DP, Johnson AL. Mass emergency water-based foam depopulation of poultry. Avian diseases 2012; 56: 891-6.
  • Beran J, Abdel-Messih IA, Raupachova J, Hobzova L, Fragapane E. A phase III, randomized, open-label study to assess the tolerability and immunogenicity of an H5N1 influenza vaccine administered to healthy adults with a 1-, 2-, 3-, or 6-week interval between first and second doses. Clinical therapeutics 2010; 32: 2186-97.
  • Cuhaci Çakir B, Beyazova U, Kemaloğlu YK, Özkan S, Gündüz B, Özdek A. Effectiveness of pandemic influenza A/H1N1 vaccine for prevention of otitis media in children. European journal of pediatrics 2012; 171: 1667-71.
  • Desrosiers M, Ferguson B, Klossek JM, Drugeon H, Mösges R. Clinical efficacy and time to symptom resolution of 5-day telithromycin versus 10-day amoxicillin-clavulanate in the treatment of acute bacterial sinusitis. Current medical research and opinion 2008; 24: 1691-702.
  • Sener M, Gürsel G, Türktaş H. Effects of inactivated influenza virus vaccination on bronchial reactivity symptom scores and peak expiratory flow variability in patients with asthma. The Journal of asthma : official journal of the Association for the Care of Asthma 1999; 36: 165-9.
  • McLean HQ, Levine MZ, King JP, Flannery B, Belongia EA. Serologic response to sequential vaccination with enhanced influenza vaccines: Open label randomized trial among adults aged 65-74 years. Vaccine 2021; 39: 7146-52.
  • Oğuz F, Unüvar E, Süoğlu Y, et al. Etiology of acute otitis media in childhood and evaluation of two different protocols of antibiotic therapy: 10 days cefaclor vs. 3 days azitromycin. International journal of pediatric otorhinolaryngology 2003; 67: 43-51.
  • Zengin E, Sarper N. Humoral immunity to diphtheria, tetanus, measles, and hemophilus influenzae type b in children with acute lymphoblastic leukemia and response to re-vaccination. Pediatric blood & cancer 2009; 53: 967-72.
  • Havasi A, Visan S, Cainap C, Cainap SS, Mihaila AA, Pop L-A. Influenza A, influenza B, and SARS-CoV-2 similarities and differences - a focus on diagnosis. Front Microbiol 2022; 13: 908525-32.
  • Cheng A, Riedel S, Arnaout R, Kirby JE. Verification of the Abbott Alinity m Resp-4-Plex assay for detection of SARS-CoV-2, influenza A/B, and respiratory syncytial virus. Diagnostic microbiology and infectious disease 2022; 102: 115575.
  • Zhen W, Manji R, Smith E, Wuitschick J, Lucic D, Berry GJ. Evaluation of the alinity m Resp-4-Plex assay for the detection of severe acute respiratory syndrome coronavirus 2, influenza A virus, influenza B virus, and respiratory syncytial virus. Microbiol Spectrum 2022; 10: e0109021.
  • Reina J, Padilla E, Alonso F, Ruiz De Gopegui E, Munar M, Mari M. Evaluation of a new dot blot enzyme immunoassay (directigen flu A+B) for simultaneous and differential detection of influenza a and B virus antigens from respiratory samples. J Clin Microbiol 2002; 40: 3515-7.
  • Brokstad KA, Cox RJ, Eriksson JC, Olofsson J, Jonsson R, Davidsson A. High prevalence of influenza specific antibody secreting cells in nasal mucosa. Scand J Immunol 2001; 54: 243-7.

Determination of the frequency of influenza-A and B antigens in swab samples in differentiating the diagnosis of influenza infection from other causes of upper respiratory tract infection

Year 2023, Volume: 6 Issue: 1, 178 - 182, 12.01.2023
https://doi.org/10.32322/jhsm.1216358

Abstract

Aim: The present study aimed to determine the frequency of influenza-A and B antigens in swab samples and to examine their potential changes at the time of initial diagnosis in differentiating the diagnosis of influenza infection from other causes of upper respiratory tract infection by physical examination and vital clinical signs in the emergency room.
Material and Method: This retrospective cross-sectional descriptive research analyzed 113 patients with Influenza-A (n:8) and B (n:15) over the age of 18 who applied to the emergency department in the last three years, were diagnosed with acute upper respiratory tract and underwent nasopharyngeal swab sampling were included in the study. The data of the patients were accessed digitally from the University hospital database.
Results: The headache score was higher, while there was no difference between vital clinical signs and those with positive or negative swab tests (p>0.05). White blood cells in blood count parameters were lower in the Influenza test-positive group (p<0.0001), platelet distribution width (p=0.006), and monocyte counts (p=0.008) were significantly higher in Influenza positive patients than negative ones. The influenza swab test was not positive in any patient with tonsillar crypt (p>0.05).
Conclusion: Influenza infections should be examined in detail in terms of costs to both public health and social security institutions, considering the burdens of diagnosis and treatment.

References

  • Choi N, Edginton HD, Griffin CE, Angus JC. Comparison of two ear cytological collection techniques in dogs with otitis externa. Veterinary Dermatol 2018; 29: 413-e136.
  • Duvignaud A, Lhomme E, Pistone T, et al. Home Treatment of Older People with Symptomatic SARS-CoV-2 Infection (COVID-19): A structured Summary of a Study Protocol for a Multi-Arm Multi-Stage (MAMS) randomized trial to evaluate the efficacy and tolerability of several experimental treatments to reduce the risk of hospitalisation or death in outpatients aged 65 years or older (COVERAGE trial). Trials 2020; 21: 846.
  • Hirsch A, Katz MA, Laufer Peretz A, et al. Study of Healthcare Personnel with Influenza and other Respiratory Viruses in Israel (SHIRI): study protocol. BMC Infect Dis 2018; 18: 550.
  • McDaniel T, Wilson DK, Coulon MS, Sweeney AM, Van Horn ML. Interaction of neighborhood and genetic risk on waist circumference in African-American adults: a longitudinal study. Ann Behav Med 2021; 55: 708-19.
  • Maignan M, Viglino D, Hablot M, et al. Diagnostic accuracy of a rapid RT-PCR assay for point-of-care detection of influenza A/B virus at emergency department admission: A prospective evaluation during the 2017/2018 influenza season. PloS one 2019; 14: e0216308.
  • McIlwain DR, Chen H, Apkarian M, et al. Performance of BioFire array or QuickVue influenza A + B test versus a validation qPCR assay for detection of influenza A during a volunteer A/California/2009/H1N1 challenge study. Virol J 2021; 18: 45.
  • Marshall HS, McMillan M, Koehler A, et al. B Part of It School Leaver protocol: an observational repeat cross-sectional study to assess the impact of a meningococcal serogroup B (4CMenB) vaccine programme on carriage of Neisseria meningitidis. BMJ Open 2019; 9: e027233.
  • Abadoğlu O, Mungan D, Paşaoglu G, Celík G, Misirligil Z. Influenza vaccination in patients with asthma: effect on the frequency of upper respiratory tract infections and exacerbations. J Asthma 2004; 41: 279-83.
  • Anar C, Bicmen C, Yapicioglu S, Unsal I, Halilcolar H, Yilmaz U. Evaluation of clinical data and antibody response following influenza vaccination in patients with chronic obstructive pulmonary disease. New Microbiologica 2010; 33: 117-27.
  • Benson ER, Alphin RL, Rankin MK, Caputo MP, Hougentogler DP, Johnson AL. Mass emergency water-based foam depopulation of poultry. Avian diseases 2012; 56: 891-6.
  • Beran J, Abdel-Messih IA, Raupachova J, Hobzova L, Fragapane E. A phase III, randomized, open-label study to assess the tolerability and immunogenicity of an H5N1 influenza vaccine administered to healthy adults with a 1-, 2-, 3-, or 6-week interval between first and second doses. Clinical therapeutics 2010; 32: 2186-97.
  • Cuhaci Çakir B, Beyazova U, Kemaloğlu YK, Özkan S, Gündüz B, Özdek A. Effectiveness of pandemic influenza A/H1N1 vaccine for prevention of otitis media in children. European journal of pediatrics 2012; 171: 1667-71.
  • Desrosiers M, Ferguson B, Klossek JM, Drugeon H, Mösges R. Clinical efficacy and time to symptom resolution of 5-day telithromycin versus 10-day amoxicillin-clavulanate in the treatment of acute bacterial sinusitis. Current medical research and opinion 2008; 24: 1691-702.
  • Sener M, Gürsel G, Türktaş H. Effects of inactivated influenza virus vaccination on bronchial reactivity symptom scores and peak expiratory flow variability in patients with asthma. The Journal of asthma : official journal of the Association for the Care of Asthma 1999; 36: 165-9.
  • McLean HQ, Levine MZ, King JP, Flannery B, Belongia EA. Serologic response to sequential vaccination with enhanced influenza vaccines: Open label randomized trial among adults aged 65-74 years. Vaccine 2021; 39: 7146-52.
  • Oğuz F, Unüvar E, Süoğlu Y, et al. Etiology of acute otitis media in childhood and evaluation of two different protocols of antibiotic therapy: 10 days cefaclor vs. 3 days azitromycin. International journal of pediatric otorhinolaryngology 2003; 67: 43-51.
  • Zengin E, Sarper N. Humoral immunity to diphtheria, tetanus, measles, and hemophilus influenzae type b in children with acute lymphoblastic leukemia and response to re-vaccination. Pediatric blood & cancer 2009; 53: 967-72.
  • Havasi A, Visan S, Cainap C, Cainap SS, Mihaila AA, Pop L-A. Influenza A, influenza B, and SARS-CoV-2 similarities and differences - a focus on diagnosis. Front Microbiol 2022; 13: 908525-32.
  • Cheng A, Riedel S, Arnaout R, Kirby JE. Verification of the Abbott Alinity m Resp-4-Plex assay for detection of SARS-CoV-2, influenza A/B, and respiratory syncytial virus. Diagnostic microbiology and infectious disease 2022; 102: 115575.
  • Zhen W, Manji R, Smith E, Wuitschick J, Lucic D, Berry GJ. Evaluation of the alinity m Resp-4-Plex assay for the detection of severe acute respiratory syndrome coronavirus 2, influenza A virus, influenza B virus, and respiratory syncytial virus. Microbiol Spectrum 2022; 10: e0109021.
  • Reina J, Padilla E, Alonso F, Ruiz De Gopegui E, Munar M, Mari M. Evaluation of a new dot blot enzyme immunoassay (directigen flu A+B) for simultaneous and differential detection of influenza a and B virus antigens from respiratory samples. J Clin Microbiol 2002; 40: 3515-7.
  • Brokstad KA, Cox RJ, Eriksson JC, Olofsson J, Jonsson R, Davidsson A. High prevalence of influenza specific antibody secreting cells in nasal mucosa. Scand J Immunol 2001; 54: 243-7.
There are 22 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Original Article
Authors

Ali Sağlık 0000-0002-3216-0303

Early Pub Date January 9, 2023
Publication Date January 12, 2023
Published in Issue Year 2023 Volume: 6 Issue: 1

Cite

AMA Sağlık A. Determination of the frequency of influenza-A and B antigens in swab samples in differentiating the diagnosis of influenza infection from other causes of upper respiratory tract infection. J Health Sci Med / JHSM. January 2023;6(1):178-182. doi:10.32322/jhsm.1216358

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