Kronik koroner arter total oklüzyonlu hastalarda fragmente QRS, QT dispersiyonu ile kollateral dolaşım arasındaki ilişki

Year 2025, Volume: 8 Issue: 2, 356 - 360, 21.03.2025

Serdar Gökhan Nurkoç , Orhan Karayiğit , İmam Günay

https://doi.org/10.32322/jhsm.1627315

Abstract

Amaç: Düzeltilmiş QT dağılımı (QTcD), uzamış QT dağılımı (QTD) ve fragmente QRS (fQRS), kardiyak aritmiler için yüksek risk göstergeleri olarak bilinir. Bu bağlamda, araştırmamız, kronik total koroner arter oklüzyonu olan hastalarda kollateral dolaşımın (CCC) QTD ve fQRS üzerindeki rolünü değerlendirmeyi amaçlamıştır.
Yöntemler: Çalışma, toplamda 131 CCC'li katılımcıyı inceledi. Katılımcılar, Rentrop sınıflamasına göre iki gruba ayrıldı: Grup 1 (Rentrop 0 ve 1) ve Grup 2 (Rentrop 2 ve 3). Demografik veriler, laboratuvar sonuçları ve elektrokardiyogram bulguları retrospektif olarak analiz edilmiştir.
Bulgular: Zayıf ve iyi kollateral gruplar arasında QTcD (91,3±21,6 vs 57,2±26,2, p<0,001), QTD (87,6±21,3 vs 55,2±26,2, p<0,001) ve fQRS varlığı (139,5±8,0 vs 128,1±13,1, p<0,001) açısından anlamlı bir değişkenlik gözlemlenmiştir. Korelasyon analizi, Rentrop sınıflaması ile diyabet, kreatinin düzeyleri, QTD, QTcD ve fQRS varlığı arasında anlamlı bir ilişki olduğunu göstermiştir.
Sonuç: Yetersiz gelişmiş CCC, daha yüksek QTcD, QTD ve fQRS ile ilişkilidir. Bu parametreler, QTD, QTcD ve fQRS, koroner arter hastalığı olan bireylerde CCC kalitesini tahmin etmede önemli, kolay erişilebilir ve etkili araçlar olabilir. Bununla birlikte, bu sonuçlar daha fazla araştırma ile incelenmelidir.

Keywords

Fragmente QRS, koroner kollateral dolaşım, QT dağılımı

The relationship between QT dispersion, fragmented QRS, and collateral circulation in patients with chronic total coronary artery occlusion

Abstract

Aims: Corrected QT dispersion (QTcD), prolonged QT dispersion (QTD), and fragmented QRS (fQRS) are known as indicators of high risk for cardiac arrhythmias. Within this context, our research was conducted to assess the role of coronary collateral circulation (CCC) on QTD and fQRS in participants with chronic total coronary artery occlusion.
Methods: This study examined 131 participants with CCC in total. The participants were divided into two groups based on the Rentrop classification: group 1 (Rentrop 0 and 1) and group 2 (rentrop 2 and 3). Demographic data, laboratory results, and electrocardiogram findings were analyzed retrospectively.
Results: Significantly, variability was observed between the poor and good collateral groups in terms of QTcD (91.3±21.6 vs 57.2±26.2, p<0.001), QTD (87.6±21.3 vs. 55.2±26.2, p<0.001), and the presence of fQRS (139.5±8.0 vs. 128.1±13.1, p<0.001). Correlation analysis indicated a significant connection between the Rentrop classification and diabetes mellitus, creatinine levels, QTD, QTcD, and the existence of fQRS.
Conclusion: Poorly developed CCC was associated with increased QTcD, QTD, and the presence of fQRS. These parameters QTD, QTcD, and fQRS may serve as important, easily accessible, and effective tools in predicting the quality of CCC in individuals with coronary artery disorder. Nevertheless, these outcomes should be investigated through further research.

Keywords

Fragmented QRS, coronary collateral circulation, QT dispersion

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