Kanser, dünya genelinde yüksek mortalite ve morbidite oranlarına sahip karmaşık bir hastalık grubudur. Bu hastalık grubunda kullanılan tedavi yöntemleri, yaşam kalitesini önemli ölçüde etkileyen cilt ve tırnak toksisiteleri, el-ayak sendromu ve periferik nöropati gibi yan etkilere yol açabilmektedir. Podoloji bilimi, bu etkilerin önlenmesi ve yönetilmesi açısından kritik bir rol oynamaktadır. Bu derleme, kanser tedavilerinde sıkça görülen ayak sağlığı sorunlarını, bu sorunların patofizyolojisini ve multidisipliner yaklaşımla sunulabilecek podolojik çözümleri sistematik bir şekilde ele almayı amaçlamaktadır. Ayrıca, Podologlar ve onkoloji uzmanlarının iş birliği ile ayak sağlığının korunmasının tedavi sürecindeki katkıları vurgulanmıştır. Derlemede, kemoterapi, radyoterapi ve immünoterapinin ayak sağlığı üzerindeki etkileri detaylandırılmış ve bu etkilerin yönetimi için uygulamalı öneriler sunulmuştur.
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Cancer comprises a heterogeneous group of diseases associated with substantial global mortality and morbidity. Therapeutic modalities for these diseases frequently produce adverse effects-most notably skin and nail toxicities, hand-foot syndrome (HFS; palmar-plantar erythrodysesthesia), and peripheral neuropathy-that can markedly diminish patients’ quality of life. Podiatric care is therefore critical for preventing and mitigating these sequelae. In this review, we systematically examine the foot-related complications of cancer therapy, describe their underlying pathophysiology, and delineate multidisciplinary podiatric interventions. We also highlight the benefits of close collaboration between podiatrists and oncology specialists in maintaining foot health during treatment. Finally, we summarise the specific effects of chemotherapy, radiotherapy, and immunotherapy on the feet and provide evidence-based recommendations for their management.
ETHICS COMMITTEE APPROVAL WAS NOT OBTAINED FOR THE REVIEW ARTICLE.
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Primary Language | English |
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Subjects | Dermatology, Cancer Therapy (Excl. Chemotherapy and Radiation Therapy), Preventative Health Care, Podiatry |
Journal Section | Review |
Authors | |
Project Number | None |
Publication Date | May 30, 2025 |
Submission Date | January 24, 2025 |
Acceptance Date | May 20, 2025 |
Published in Issue | Year 2025 Volume: 8 Issue: 3 |
Interuniversity Board (UAK) Equivalency: Article published in Ulakbim TR Index journal [10 POINTS], and Article published in other (excuding 1a, b, c) international indexed journal (1d) [5 POINTS].
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Our journal has been indexed in DOAJ as of May 18, 2020.
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Articles published in the Journal of Health Sciences and Medicine have open access and are licensed under the Creative Commons CC BY-NC-ND 4.0 International License.