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Antibacterial, Antioxidant and DNA Interaction Properties of Cistus creticus L. Extracts

Year 2019, Volume: 14 Issue: 3, 110 - 115, 30.09.2019

Abstract

Medicinal plants
are a natural source that possesses significant biological functions. Cistus species which are medical plant
are of antibacterial, antioxidant and cytotoxic activities. This study was perfpormed
to investigate the antibacterial, antioxidant and DNA interaction properties of
Cistus creticus extracts.



Samples of Cistus creticus L. were obtained in May
2018 in the region of Amasya. The different extract of Cistus criticus leaves was obtained by using soxhlet apparatus for
4 hours. Antibacterial activity of extracts was tested against four Gram positive
and four Gram negative by the disc diffusion method. Antioxidant activities of
extracts were determined with DPPH radical scavenging, ferric reducing and
metal chelating methods. The ability to repair the plasmid DNA breaks created
by hydroxyl radicals was also determine using pUC18 plasmid DNA. 



As a result,
Cistus creticus. extracts has strong
inhibitory activity against all tested bacteria. The chloroform extract was
also very effective against Gram positive bacteria especially Bacillus cereus. Among the Gram negative
bacteria, the most susceptible bacterium was identified as Pseudomonas aeruginosa. Moreover, ethanol extracts had repair
effects on plasmid DNA in H2O2 condition. Among the
different extracts
of Cistus
creticus
chloroform extract showed the highest in vitro
antioxidant

activity.



In this study, Cistus creticus collected from Amasya has shown significant
antibacterial, antioxidant and DNA interaction activity and could be therefore
a useful source in the discovery of new antibacterial and antioxidant
compounds. However, the use of extracts as a complement to the treatment
requires further research to thoroughly understand the activities and
interactions with recommended medicines.

References

  • Prof. Dr. Birsen Aydınbirsenki@gmail.com
  • Assist Prof Melek Çölmelekcol@hotmail.com
Year 2019, Volume: 14 Issue: 3, 110 - 115, 30.09.2019

Abstract


References

  • Prof. Dr. Birsen Aydınbirsenki@gmail.com
  • Assist Prof Melek Çölmelekcol@hotmail.com
There are 2 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Articles
Authors

Dudu Duygu Kılıç

Belgin Sırıken

Ömer Ertürk This is me

Güler Tanrıkulu This is me

Melek Gül This is me

Ceren Baskan 0000-0001-7849-4459

Publication Date September 30, 2019
Acceptance Date September 18, 2019
Published in Issue Year 2019 Volume: 14 Issue: 3

Cite

APA Kılıç, D. D., Sırıken, B., Ertürk, Ö., Tanrıkulu, G., et al. (2019). Antibacterial, Antioxidant and DNA Interaction Properties of Cistus creticus L. Extracts. Journal of International Environmental Application and Science, 14(3), 110-115.
AMA Kılıç DD, Sırıken B, Ertürk Ö, Tanrıkulu G, Gül M, Baskan C. Antibacterial, Antioxidant and DNA Interaction Properties of Cistus creticus L. Extracts. J. Int. Environmental Application & Science. September 2019;14(3):110-115.
Chicago Kılıç, Dudu Duygu, Belgin Sırıken, Ömer Ertürk, Güler Tanrıkulu, Melek Gül, and Ceren Baskan. “Antibacterial, Antioxidant and DNA Interaction Properties of Cistus Creticus L. Extracts”. Journal of International Environmental Application and Science 14, no. 3 (September 2019): 110-15.
EndNote Kılıç DD, Sırıken B, Ertürk Ö, Tanrıkulu G, Gül M, Baskan C (September 1, 2019) Antibacterial, Antioxidant and DNA Interaction Properties of Cistus creticus L. Extracts. Journal of International Environmental Application and Science 14 3 110–115.
IEEE D. D. Kılıç, B. Sırıken, Ö. Ertürk, G. Tanrıkulu, M. Gül, and C. Baskan, “Antibacterial, Antioxidant and DNA Interaction Properties of Cistus creticus L. Extracts”, J. Int. Environmental Application & Science, vol. 14, no. 3, pp. 110–115, 2019.
ISNAD Kılıç, Dudu Duygu et al. “Antibacterial, Antioxidant and DNA Interaction Properties of Cistus Creticus L. Extracts”. Journal of International Environmental Application and Science 14/3 (September 2019), 110-115.
JAMA Kılıç DD, Sırıken B, Ertürk Ö, Tanrıkulu G, Gül M, Baskan C. Antibacterial, Antioxidant and DNA Interaction Properties of Cistus creticus L. Extracts. J. Int. Environmental Application & Science. 2019;14:110–115.
MLA Kılıç, Dudu Duygu et al. “Antibacterial, Antioxidant and DNA Interaction Properties of Cistus Creticus L. Extracts”. Journal of International Environmental Application and Science, vol. 14, no. 3, 2019, pp. 110-5.
Vancouver Kılıç DD, Sırıken B, Ertürk Ö, Tanrıkulu G, Gül M, Baskan C. Antibacterial, Antioxidant and DNA Interaction Properties of Cistus creticus L. Extracts. J. Int. Environmental Application & Science. 2019;14(3):110-5.

“Journal of International Environmental Application and Science”