DENTAL FOLLICLE: ROLE IN DEVELOPMENT OF ODONTOGENIC CYSTS AND TUMOURS Dental Folikül: Odontojenik Kist ve Tümörlerin Oluşumundaki Rolü

Abstract

ABSTRACT
Dental follicle is ecto-mesenchymal derived component of the tooth germ, adjacent to the crown of unerupted tooth. It has many roles during tooth development and eruption. During the impacted tooth surgery, pericoronal and dental follicular tissues are enucleating. However, in rare cases they are submitting for histopathologic evaluation, although it is known, that these tissues are responsible for the occurrence and development of pathologic conditions, such as infections, odontogenic cysts, and tumors.Dental follicle was the subject of many immunohistochemical studies, which have shown a proliferative potential of the dental follicle cells justifying a profilactic removal of the impacted teeth.
According to review of relevant literature, the aim of this article is to describe and discuss importance of dental follicle in oral and maxillofacial surgery.
Kerwords: Dental follicle, dentigerous cyst, impacted tooth, stem cells
ÖZ
Dental folikül diş germini ektomezenkimal bağ dokusundan oluşturan, dişin kronun etrafında olan ve diş gelişiminde ve sürmesinde önemli rol oynayan yapıdır. Gömük7 diş operasyonu sırasında, pe-rikoronal ve dental folikül dokuları enükle edilmektedir. Ancak bu dokuları, enfeksiyon, odontojenik kist ve tümör gibi patolojik durumların gelişiminden sorumlu olduğu halde, nadiren histopatolojik incelemeleri yapılmaktadır. Pek çok immunohistokimyasal çalışmalar dental folikülü incelerken, onun proliferatif potensiyelini göstererek, gömük dişlerin profilaktik çekimlerini önermektedir. Konu ile ilgili literatüre göre, bu derlemenin amacı dental folikülün oral ve maksillofasyal cerrahisinde önemli rol olduğunu göstermektir.
Anahtar kelimeler: Dental folikül, dentigeröz kist, gömük diş, kök hücreler

Keywords

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Dental Folikül: Odontojenik Kist ve Tümörlerin Oluşumundaki Rolü

Abstract

Dental folikül diş germini ektomezenkimal bağ dokusundan oluşturan, dişin kronun etrafında olan ve diş gelişiminde ve sürmesinde önemli rol oynayan yapıdır. Gömük7 diş operasyonu sırasında, perikoronal ve dental folikül dokuları enükle edilmektedir. Ancak bu dokuları, enfeksiyon, odontojenik kist ve tümör gibi patolojik durumların gelişiminden sorumlu olduğu halde, nadiren histopatolojik incelemeleri yapılmaktadır. Pek çok immunohistokimyasal çalışmalar dental folikülü incelerken, onun proliferatif potensiyelini göstererek, gömük dişlerin profilaktik çekimlerini önermektedir. Konu ile ilgili literatüre göre, bu derlemenin amacı dental folikülün oral ve maksillofasyal cerrahisinde önemli rol olduğunu göstermektir.

Keywords

• Dental folikül, dentigeröz kist, gömük diş, kök hücreler

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34. Corresponding Author: Amila BRKİĆ Fra AndjelaZvizdovića 8, 71000 Sarajevo
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