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Molecular Detection of Leptospira in Pediatric Aseptic Meningitis

Year 2022, , 35 - 37, 15.03.2022
https://doi.org/10.5799/jmid.1086212

Abstract

ABSTRACT
Leptospirosis is a zoonotic disease caused by pathogenic Leptospira bacterial species. It is tremendously neglected, and scarce epidemiological data is present worldwide. Aseptic meningitis is a rare secondary manifestation of Leptospira infection. Molecular detection of leptospira DNA in cerebrospinal fluid (CSF) samples of children younger than two years is could be considered for diagnosis of aseptic meningitis.
A total of 50 CSF samples suspected of aseptic meningitis were collected from pediatric patients (<2 years) presenting to Omdurman Teaching Hospital in Khartoum state, Sudan, between June and September 2018. PCR was used to investigate the presence of leptospira DNA in these samples.
Out of the 50 CSF samples in our study, two samples (4%) tested positive for Leptospira DNA using PCR. Leptospira is an overlooked cause of aseptic meningitis in children, and PCR can be used for its diagnosis. J Microbiol Infect Dis 2022; 12(1):35-37.

Year 2022, , 35 - 37, 15.03.2022
https://doi.org/10.5799/jmid.1086212

Abstract

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Details

Primary Language English
Subjects Health Care Administration
Journal Section Letter to Editor
Authors

Ahmed M. H. Mohamed This is me

Sami E. A Algam This is me

Khalid A Enan This is me

Abdel Rahim M El Hussein This is me

Isam M Elkhidir This is me

Publication Date March 15, 2022
Published in Issue Year 2022

Cite

APA Mohamed, A. M. H., Algam, S. E. A., Enan, K. A., El Hussein, A. R. M., et al. (2022). Molecular Detection of Leptospira in Pediatric Aseptic Meningitis. Journal of Microbiology and Infectious Diseases, 12(01), 35-37. https://doi.org/10.5799/jmid.1086212
AMA Mohamed AMH, Algam SEA, Enan KA, El Hussein ARM, Elkhidir IM. Molecular Detection of Leptospira in Pediatric Aseptic Meningitis. J Microbil Infect Dis. March 2022;12(01):35-37. doi:10.5799/jmid.1086212
Chicago Mohamed, Ahmed M. H., Sami E. A Algam, Khalid A Enan, Abdel Rahim M El Hussein, and Isam M Elkhidir. “Molecular Detection of Leptospira in Pediatric Aseptic Meningitis”. Journal of Microbiology and Infectious Diseases 12, no. 01 (March 2022): 35-37. https://doi.org/10.5799/jmid.1086212.
EndNote Mohamed AMH, Algam SEA, Enan KA, El Hussein ARM, Elkhidir IM (March 1, 2022) Molecular Detection of Leptospira in Pediatric Aseptic Meningitis. Journal of Microbiology and Infectious Diseases 12 01 35–37.
IEEE A. M. H. Mohamed, S. E. A. Algam, K. A. Enan, A. R. M. El Hussein, and I. M. Elkhidir, “Molecular Detection of Leptospira in Pediatric Aseptic Meningitis”, J Microbil Infect Dis, vol. 12, no. 01, pp. 35–37, 2022, doi: 10.5799/jmid.1086212.
ISNAD Mohamed, Ahmed M. H. et al. “Molecular Detection of Leptospira in Pediatric Aseptic Meningitis”. Journal of Microbiology and Infectious Diseases 12/01 (March 2022), 35-37. https://doi.org/10.5799/jmid.1086212.
JAMA Mohamed AMH, Algam SEA, Enan KA, El Hussein ARM, Elkhidir IM. Molecular Detection of Leptospira in Pediatric Aseptic Meningitis. J Microbil Infect Dis. 2022;12:35–37.
MLA Mohamed, Ahmed M. H. et al. “Molecular Detection of Leptospira in Pediatric Aseptic Meningitis”. Journal of Microbiology and Infectious Diseases, vol. 12, no. 01, 2022, pp. 35-37, doi:10.5799/jmid.1086212.
Vancouver Mohamed AMH, Algam SEA, Enan KA, El Hussein ARM, Elkhidir IM. Molecular Detection of Leptospira in Pediatric Aseptic Meningitis. J Microbil Infect Dis. 2022;12(01):35-7.