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Daptomycin for the treatment of daptomycin nonsusceptible Enterococcus faecium bacteremia

Year 2014, , 36 - 38, 01.03.2014
https://doi.org/10.5799/ahinjs.02.2014.01.0122

Abstract

Dilek Yildiz Sevgi, Alper Gunduz, Ahmet Şanlı Konuklar, Murat Musluman, Feyzullah Tuncer, Okan Derin, Banu Bayraktar, Nuray Uzun The best therapeutic options for serious infections due to daptomycin nonsusceptible Enterococcus faecium (DNSE) remain unclear. We report the use of daptomycin for the treatment of DNSE bacteremia. To our knowledge, it is the fırst case of DNSE infection which successfully treated with daptomycin monotherapy in the literature.

References

  • Diaz Granados CA, Zimmer SM, Klein M et, al. Comparison of mortality associated with vancomycin-resistant and van- comycin-susceptible enterococcal bloodstream infections: a metaanalysis. Clin Infect Dis 2005;41:327-333.
  • Murray BE. Treatment of enterococcal infections. In: UpTo Date, Sexton DJ (ed), 2013.
  • Casapao AM, Kullar R, Davis SL, et al. Multicenter study of high-dose daptomycin for treatment of enterococcal infec- tions. Antimicrob Agents Chemother 2013;57:4190-4196.
  • Safdar N, Andes D, Craig WA. In vivo pharmacodynamic activ- ity of daptomycin. Antimicrob Agents Chemother 2004;48:63- 68.
  • Kelesidis T, Humphries R, Uslan DZ, Pegues DA. Daptomycin nonsusceptible enterococci: an emerging challenge for clini- cians. Clin Infect Dis 2011;52:228-234.
  • Cesur S, Irmak H, Simşek H, et al. Evaluation of antibiotic susceptibilities and VISA-VRSA rates among MRSA strains isolated from hospitalized patients in intensive care units of hospitals in seven provinces of Turkey. Mikrobiyol Bul 2012;46:352-358.
  • Yilmaz G, Eruz E, Coşkun B, et al. Ülkemizden ilk duyarlı ol- mayan (non-susceptible) S. aureus enfeksiyonu. EKMUD Congress,. Istanbul, Turkey May 2012.
  • Grim SA, Hong I, Freeman J, et al. Daptomycin for the treat- ment of vancomycin-resistant enterococcal infections. J Anti- microb Chemother 2009;63:414-416.
  • Gallagher JC, Perez ME, Marino EA, et al. Daptomycin ther- apy for vancomycin-resistant enterococcal bacteremia: a retrospective case series of 30 patients. Pharmacotherapy 2009;29:792-799.
  • Mohr JF, Friedrich LV, Yankelev S, Lamp KC. Daptomycin for the treatment of enterococcal bacteraemia: results from the Cubicin Outcomes Registry and Experience (CORE). Int J Antimicrob Agents 2009;33:543-548.
  • Canton R, Ruiz-Garbajosa P, Chaves RL, Johnson AP. A po- tential role for daptomycin in enterococcal infections: what is the evidence? J Antimicrob Chemother 2010;65:1126-1136.
  • Clinical Laboratory Standards Institute: Performance stan- dards for antimicrobial susceptibility testing. 20th Informa- tional Supplement. CLSI M100-S20. Clinical and Laboratory Standards Institute, Wayne, PA.
  • King EA, McCoy D, Desai S, et al. Vancomycin-resistant en- terococcal bacteraemia and daptomycin: are higher doses necessary? J Antimicrob Chemother 2011;66:2112-2118.
  • Dvorchik BH, Brazier D, DeBruin MF, Arbeit RD. Daptomy- cin pharmacokinetics and safety following administration of escalating doses once daily to healthy subjects. Antimicrob Agents Chemother 2003;47:1318-1323.
  • Benvenuto M, Benziger DP, Yankelev S, Vigliani G. Pharma- cokinetics and tolerability of daptomycin at doses up to 12 milligrams per kilogram of body weight once daily in healthy volunteers. Antimicrob Agents Chemother 2006;50:3245- 3249.

Daptomycin for the treatment of daptomycin nonsusceptible Enterococcus faecium bacteremia

Year 2014, , 36 - 38, 01.03.2014
https://doi.org/10.5799/ahinjs.02.2014.01.0122

Abstract

Daptomisine duyarlı olmayan Enterococcus faecium (DNSE)’a bağlı ciddi enfeksiyonlarda en iyi tedavi seçeneği belirsizdir. Burada DNSE bakteriyemisi olan bir olguda daptomisin kullanımı tecrübemizi paylaştık. Bildiğimiz kadarı ile literatürde daptomisin monoterapisi ile başarılı tedavi edilen ilk olgudur

References

  • Diaz Granados CA, Zimmer SM, Klein M et, al. Comparison of mortality associated with vancomycin-resistant and van- comycin-susceptible enterococcal bloodstream infections: a metaanalysis. Clin Infect Dis 2005;41:327-333.
  • Murray BE. Treatment of enterococcal infections. In: UpTo Date, Sexton DJ (ed), 2013.
  • Casapao AM, Kullar R, Davis SL, et al. Multicenter study of high-dose daptomycin for treatment of enterococcal infec- tions. Antimicrob Agents Chemother 2013;57:4190-4196.
  • Safdar N, Andes D, Craig WA. In vivo pharmacodynamic activ- ity of daptomycin. Antimicrob Agents Chemother 2004;48:63- 68.
  • Kelesidis T, Humphries R, Uslan DZ, Pegues DA. Daptomycin nonsusceptible enterococci: an emerging challenge for clini- cians. Clin Infect Dis 2011;52:228-234.
  • Cesur S, Irmak H, Simşek H, et al. Evaluation of antibiotic susceptibilities and VISA-VRSA rates among MRSA strains isolated from hospitalized patients in intensive care units of hospitals in seven provinces of Turkey. Mikrobiyol Bul 2012;46:352-358.
  • Yilmaz G, Eruz E, Coşkun B, et al. Ülkemizden ilk duyarlı ol- mayan (non-susceptible) S. aureus enfeksiyonu. EKMUD Congress,. Istanbul, Turkey May 2012.
  • Grim SA, Hong I, Freeman J, et al. Daptomycin for the treat- ment of vancomycin-resistant enterococcal infections. J Anti- microb Chemother 2009;63:414-416.
  • Gallagher JC, Perez ME, Marino EA, et al. Daptomycin ther- apy for vancomycin-resistant enterococcal bacteremia: a retrospective case series of 30 patients. Pharmacotherapy 2009;29:792-799.
  • Mohr JF, Friedrich LV, Yankelev S, Lamp KC. Daptomycin for the treatment of enterococcal bacteraemia: results from the Cubicin Outcomes Registry and Experience (CORE). Int J Antimicrob Agents 2009;33:543-548.
  • Canton R, Ruiz-Garbajosa P, Chaves RL, Johnson AP. A po- tential role for daptomycin in enterococcal infections: what is the evidence? J Antimicrob Chemother 2010;65:1126-1136.
  • Clinical Laboratory Standards Institute: Performance stan- dards for antimicrobial susceptibility testing. 20th Informa- tional Supplement. CLSI M100-S20. Clinical and Laboratory Standards Institute, Wayne, PA.
  • King EA, McCoy D, Desai S, et al. Vancomycin-resistant en- terococcal bacteraemia and daptomycin: are higher doses necessary? J Antimicrob Chemother 2011;66:2112-2118.
  • Dvorchik BH, Brazier D, DeBruin MF, Arbeit RD. Daptomy- cin pharmacokinetics and safety following administration of escalating doses once daily to healthy subjects. Antimicrob Agents Chemother 2003;47:1318-1323.
  • Benvenuto M, Benziger DP, Yankelev S, Vigliani G. Pharma- cokinetics and tolerability of daptomycin at doses up to 12 milligrams per kilogram of body weight once daily in healthy volunteers. Antimicrob Agents Chemother 2006;50:3245- 3249.
There are 15 citations in total.

Details

Primary Language English
Journal Section Case Report
Authors

Dilek Yildiz Sevgi This is me

Alper Gunduz This is me

Ahmet Şanlı Konuklar This is me

Murat Musluman This is me

Feyzullah Tuncer This is me

Okan Derin This is me

Banu Bayraktar This is me

Nuray Uzun This is me

Publication Date March 1, 2014
Published in Issue Year 2014

Cite

APA Sevgi, D. Y., Gunduz, A., Konuklar, A. Ş., Musluman, M., et al. (2014). Daptomycin for the treatment of daptomycin nonsusceptible Enterococcus faecium bacteremia. Journal of Microbiology and Infectious Diseases, 4(01), 36-38. https://doi.org/10.5799/ahinjs.02.2014.01.0122
AMA Sevgi DY, Gunduz A, Konuklar AŞ, Musluman M, Tuncer F, Derin O, Bayraktar B, Uzun N. Daptomycin for the treatment of daptomycin nonsusceptible Enterococcus faecium bacteremia. J Microbil Infect Dis. March 2014;4(01):36-38. doi:10.5799/ahinjs.02.2014.01.0122
Chicago Sevgi, Dilek Yildiz, Alper Gunduz, Ahmet Şanlı Konuklar, Murat Musluman, Feyzullah Tuncer, Okan Derin, Banu Bayraktar, and Nuray Uzun. “Daptomycin for the Treatment of Daptomycin Nonsusceptible Enterococcus Faecium Bacteremia”. Journal of Microbiology and Infectious Diseases 4, no. 01 (March 2014): 36-38. https://doi.org/10.5799/ahinjs.02.2014.01.0122.
EndNote Sevgi DY, Gunduz A, Konuklar AŞ, Musluman M, Tuncer F, Derin O, Bayraktar B, Uzun N (March 1, 2014) Daptomycin for the treatment of daptomycin nonsusceptible Enterococcus faecium bacteremia. Journal of Microbiology and Infectious Diseases 4 01 36–38.
IEEE D. Y. Sevgi, A. Gunduz, A. Ş. Konuklar, M. Musluman, F. Tuncer, O. Derin, B. Bayraktar, and N. Uzun, “Daptomycin for the treatment of daptomycin nonsusceptible Enterococcus faecium bacteremia”, J Microbil Infect Dis, vol. 4, no. 01, pp. 36–38, 2014, doi: 10.5799/ahinjs.02.2014.01.0122.
ISNAD Sevgi, Dilek Yildiz et al. “Daptomycin for the Treatment of Daptomycin Nonsusceptible Enterococcus Faecium Bacteremia”. Journal of Microbiology and Infectious Diseases 4/01 (March 2014), 36-38. https://doi.org/10.5799/ahinjs.02.2014.01.0122.
JAMA Sevgi DY, Gunduz A, Konuklar AŞ, Musluman M, Tuncer F, Derin O, Bayraktar B, Uzun N. Daptomycin for the treatment of daptomycin nonsusceptible Enterococcus faecium bacteremia. J Microbil Infect Dis. 2014;4:36–38.
MLA Sevgi, Dilek Yildiz et al. “Daptomycin for the Treatment of Daptomycin Nonsusceptible Enterococcus Faecium Bacteremia”. Journal of Microbiology and Infectious Diseases, vol. 4, no. 01, 2014, pp. 36-38, doi:10.5799/ahinjs.02.2014.01.0122.
Vancouver Sevgi DY, Gunduz A, Konuklar AŞ, Musluman M, Tuncer F, Derin O, Bayraktar B, Uzun N. Daptomycin for the treatment of daptomycin nonsusceptible Enterococcus faecium bacteremia. J Microbil Infect Dis. 2014;4(01):36-8.