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A rare cause of fever and icterus: Thyroid crisis

Year 2013, , 36 - 38, 01.03.2013
https://doi.org/10.5799/ahinjs.02.2013.01.0076

Abstract

Emine Parlak, Serpil Erol Thyroid crisis is the severe form of hyperthyroidism. The predisposing factors are mostly surgeries and additional diseases. Although the case is rare, the mortality rate is high. Here, we present a thyroid crisis case which implies infectious diseases. A 36-year-old female patient admitted to the hospital with high fever, abdominal pain, and unstable mental state. Physical examination revealed icterus, tachycardia, and hepatosplenomegaly. Serum free triiodothyronine (FT3), and free thyroxine (FT4) levels were elevated and thyroid-stimulating hormone (TSH) was highly suppressed. An infectious etiology was suspected on admission, but further investigation revealed thyroid crisis. Patients with high fever should be considered in differential diagnosis of non-infectious causes such as thyroid crisis. In these cases, early and correct diagnosis is important for prognosis.

References

  • Hsiao FC, Hung YJ, Hsieh CH, Wu LY, Shih KC, He CT. Ab- dominal pain and multi-organ dysfunction syndrome in a young woman. Am J Med Sci 2007;334:399-401.
  • Lazarus J H, Hyperthyroidism. Lancet 1997;349:339-343.
  • Kadıoğlu P. Endokrinolojide Aciller. İ.Ü. Cerrahpaşa Tıp Fakül- tesi Sürekli Tıp Eğitimi Etkinlikleri İç Hastalıklarında Aciller Sempozyum Dizisi. 2002;29:265-277.
  • Karger S, Führer D. Thyroid storm - thyrotoxic crisis: an up- date. Dtsch Med Wochenschr 2008;133:479-484.
  • Gavin LA. Thyroid crises. Med Clin North Am 1991;75:179-93.
  • Gönüllü H, Kahraman N, Akcahüseyin B, Denizlioğlu B. Tiroid Fırtınası. JAEM Article in Pres, doi:10. 5152/jaem.2011.051
  • Nayak B, Burman K. Thyrotoxicosis and Thyroid Storm. Endo- crinol Metab Clin N Am 2006;35:663-686.
  • Sasaki K, Yoshida A, Nakata Y. and et al. A Case of thyroid storm with multiple organ failure effectively treated with plas- ma exchange. Intern Med 2011;50:2801-2805.
  • Tietgens ST, Leinung MC. Thyroid storm. Med Clin North Am 1995;79:169-184.
  • Mazzaferri MEL, Skillman TG. Thyroid storm: a review of 22 episodes with special emphasis on the use of guanethidine. Arch Intern Med 1969;124:684-690.
  • Jiang YZ, Hutchinson KA, Bartelloni P, Manthous C. Thyroid Storm Presenting as Multiple Organ Dysfunction Syndrome. Chest 2000;118:877-879.
  • Howton JC. Thyroid storm presenting as coma. Ann Emerg Med 1988;17:343-345.
  • Burch HB, Wartofsky L. Life-threatening thyrotoxicosis. Thy- roid storm. Endocrinol Metab Clin North Am 1993;22:263- 277.
  • Franklyn J A, Boelaert K. Thyrotoxicosis. Lancet 2012;9821:1155-1166.

A rare cause of fever and icterus: Thyroid crisis

Year 2013, , 36 - 38, 01.03.2013
https://doi.org/10.5799/ahinjs.02.2013.01.0076

Abstract

Tiroid krizi, hipertiroidinin yaşamı tehdit edecek kadar ağırlaşması durumudur. En sık hazırlayıcı nedenler ameliyatlar ve ek hastalıklardır. Nadir görülmesine rağmen mortalite yüksektir. Bu makalede infeksiyon hastalıklarını taklit eden bir tiroid krizi olgusu sunduk. 36 yaşında bayan hasta yüksek ateş, karın ağrısı ve mental durum değişiklikleri ile hastaneye başvurdu. Fizik muayenesinde ikter, taşikardi ve hepato-splenomegalisi vardı. FT3, FT4 düzeyleri yükselmişti ve TSH oldukça baskılanmıştı. İlk başvuruda infeksiyöz bir neden düşünülen hastada yapılan tetkikler sonucu mevcut klinik tablonun tiroid krizine bağlı olduğu saptandı. Bu olgularda doğru ve erken tanı prognoz açısından önemlidir

References

  • Hsiao FC, Hung YJ, Hsieh CH, Wu LY, Shih KC, He CT. Ab- dominal pain and multi-organ dysfunction syndrome in a young woman. Am J Med Sci 2007;334:399-401.
  • Lazarus J H, Hyperthyroidism. Lancet 1997;349:339-343.
  • Kadıoğlu P. Endokrinolojide Aciller. İ.Ü. Cerrahpaşa Tıp Fakül- tesi Sürekli Tıp Eğitimi Etkinlikleri İç Hastalıklarında Aciller Sempozyum Dizisi. 2002;29:265-277.
  • Karger S, Führer D. Thyroid storm - thyrotoxic crisis: an up- date. Dtsch Med Wochenschr 2008;133:479-484.
  • Gavin LA. Thyroid crises. Med Clin North Am 1991;75:179-93.
  • Gönüllü H, Kahraman N, Akcahüseyin B, Denizlioğlu B. Tiroid Fırtınası. JAEM Article in Pres, doi:10. 5152/jaem.2011.051
  • Nayak B, Burman K. Thyrotoxicosis and Thyroid Storm. Endo- crinol Metab Clin N Am 2006;35:663-686.
  • Sasaki K, Yoshida A, Nakata Y. and et al. A Case of thyroid storm with multiple organ failure effectively treated with plas- ma exchange. Intern Med 2011;50:2801-2805.
  • Tietgens ST, Leinung MC. Thyroid storm. Med Clin North Am 1995;79:169-184.
  • Mazzaferri MEL, Skillman TG. Thyroid storm: a review of 22 episodes with special emphasis on the use of guanethidine. Arch Intern Med 1969;124:684-690.
  • Jiang YZ, Hutchinson KA, Bartelloni P, Manthous C. Thyroid Storm Presenting as Multiple Organ Dysfunction Syndrome. Chest 2000;118:877-879.
  • Howton JC. Thyroid storm presenting as coma. Ann Emerg Med 1988;17:343-345.
  • Burch HB, Wartofsky L. Life-threatening thyrotoxicosis. Thy- roid storm. Endocrinol Metab Clin North Am 1993;22:263- 277.
  • Franklyn J A, Boelaert K. Thyrotoxicosis. Lancet 2012;9821:1155-1166.
There are 14 citations in total.

Details

Primary Language English
Journal Section Case Report
Authors

Emine Parlak This is me

Serpil Erol This is me

Publication Date March 1, 2013
Published in Issue Year 2013

Cite

APA Parlak, E., & Erol, S. (2013). A rare cause of fever and icterus: Thyroid crisis. Journal of Microbiology and Infectious Diseases, 3(01), 36-38. https://doi.org/10.5799/ahinjs.02.2013.01.0076
AMA Parlak E, Erol S. A rare cause of fever and icterus: Thyroid crisis. J Microbil Infect Dis. March 2013;3(01):36-38. doi:10.5799/ahinjs.02.2013.01.0076
Chicago Parlak, Emine, and Serpil Erol. “A Rare Cause of Fever and Icterus: Thyroid Crisis”. Journal of Microbiology and Infectious Diseases 3, no. 01 (March 2013): 36-38. https://doi.org/10.5799/ahinjs.02.2013.01.0076.
EndNote Parlak E, Erol S (March 1, 2013) A rare cause of fever and icterus: Thyroid crisis. Journal of Microbiology and Infectious Diseases 3 01 36–38.
IEEE E. Parlak and S. Erol, “A rare cause of fever and icterus: Thyroid crisis”, J Microbil Infect Dis, vol. 3, no. 01, pp. 36–38, 2013, doi: 10.5799/ahinjs.02.2013.01.0076.
ISNAD Parlak, Emine - Erol, Serpil. “A Rare Cause of Fever and Icterus: Thyroid Crisis”. Journal of Microbiology and Infectious Diseases 3/01 (March 2013), 36-38. https://doi.org/10.5799/ahinjs.02.2013.01.0076.
JAMA Parlak E, Erol S. A rare cause of fever and icterus: Thyroid crisis. J Microbil Infect Dis. 2013;3:36–38.
MLA Parlak, Emine and Serpil Erol. “A Rare Cause of Fever and Icterus: Thyroid Crisis”. Journal of Microbiology and Infectious Diseases, vol. 3, no. 01, 2013, pp. 36-38, doi:10.5799/ahinjs.02.2013.01.0076.
Vancouver Parlak E, Erol S. A rare cause of fever and icterus: Thyroid crisis. J Microbil Infect Dis. 2013;3(01):36-8.