A case of cerebral abscess due to Cladophialophora bantiana

Öz

Anahtar Kelimeler

• -

A case of cerebral abscess due to Cladophialophora bantiana

Abstract

Atul Aher, Vichal Rastogi Cladophialophora bantiana is a dematiaceous fungus which belongs to family Phaeohyphomycetes. It is primarily a neurotropic fungus causing central nervous system infection. We report a case of a brain abscess in frontoparietal region in a diabetic patient caused by C. bantiana. Diagnosis was made based on the microscopy and culture of the pus material obtained after craniotomy. The patient died despite of surgical intervention and appropriate antifungal therapy.

Keywords

• cerebral abscess,Cladophialophora bantiana

References

1. Chakrabarti A. Epidemiology of central nervous system myco- ses. Neurol India 2007; 55:191-197.
2. Chandramuki A, Ramadevi MG, Shankar SK. Cerebral clado- sporiosis: A neuropathological and microbiological study. Clin Neurol Neurosurg 1983; 85:245-253.
3. Huang WM, Fan YM, Li W, Yang WW. Brain abscess caused by Cladophialophora bantiana in China. J Med Microbiol 2011; 60 (Pt 12):1872-4.
4. Kantarcioglu AS, de Hoog GS. Infections of the central ner- vous system by melanized fungi: A review of cases present- ed between 1999 and 2004. Mycoses 2004; 47:4-13.
5. Revankar SG, Sutton DA, Rinaldi MG. Primary central nervous system phaeohyphomycosis: A review of 101 cases. Clin In- fect Dis 2004; 38: 206-216
6. Chakrabarti A, Das A, Mandal J, et al. The rising trend of inva- sive zygomycosis in patients with uncontrolled diabetes mel- litus. Med Mycol 2006; 44:335-342.
7. Pellacchia V, Terenzi V, Moricca LM, Buonaccorsi S, Indrizzi E, Fini G. Brain abscess mycotic and bacterial infection in a diabetic patient: Clinical report and review of literature. J Craniofac Surg 2006; 17:578-584.
8. Lakshmi V, Padmasri C, Umabala P, Sundaram C, Panigrahi M. Cerebral phaeohyphomycosis due to Cladophialophora bantiana. Indian J Med Microbiol 2008; 26:392-395.

9. Lyons MK, Blair JE, Leslie KO. Successful treatment with voriconazole of fungal cerebral abscess due to Cladophia- lophora bantiana. Clin Neurol Neurosurg 2005; 107:532-534.
10. Fica A, Diaz MC, Luppi M, et al. Unsuccessful treatment with voriconazole of a brain abscess due to Cladophialophora bantiana. Scand J Infect Dis 2003; 35:892-893.