Pneumonic varicella in patient with inactive hepatitis B: A case report

Volume: 2 Number: 02 June 1, 2012
  • Erkan Yula
  • Özcan Deveci
  • Ersin Şükrü Erden
  • Türkan Toka Özer
  • Alicem Tekin
  • Melek Inci
EN TR

Pneumonic varicella in patient with inactive hepatitis B: A case report

Abstract

Although rarely observed, varicella zoster virus (VZV)-related pneumonia is the most serious complication of the virus, which commonly affects adults and causes high mortality rates. In this study, we describe a case of VZV pneumonia in a 29-year-old male who is an inactive Hepatitis B virus carrier. The patient presented with a 5-day history of fatigue, sore throat, fever, cough and mild dyspnea. He also had an exanthematous vesicular rash. The rash had spread all over his body surface including the hairy skin. But he was not febrile and vital signs were normal. The skin examination exhibited a diffuse polymorphic rash with papules/vesicles, pustules and crusty lesions over the whole body. Serological findings were as follows: VZV IgM positive, VZV IgG positive and HBsAg positive. His chest X-ray showed bilateral pneumonic infiltrations. The patient was prescribed valacyclovir and clarithromycin. The skin lesions disappeared after ten days and the patient made a full recovery. We conclude that an early diagnosis of VZV pneumonia, which rarely occurs in adult patients and its effective treatment with antivirals may prevent the development of serious complications.

Keywords

References

  1. Curry MP, Chopra S. Acute Viral Hepatitis. In: Mandell GL, Bennett JE, Dolin R, (eds). Principles and Practice of Infectious Diseases. 7th ed. Philadelphia: Churchill Livingstone; 2010:1577-1592.
  2. Perz JF, Armstrong GL, Farrington LA, Hutin YJ, Bell BP. The contribution of hepatitis B and hepatitis C virus infection to cirrhosis and primary liver cancer worldwide. J Hepatol 2006; 45:529-538.
  3. Tong MJ, Hsu LY, Chang PW, Blatt LM. Evaluation of current treatment recommendations for chronic hepatitis B: a 2011 update. J Gastroenterol Hepatol 2011; 26:829-835.
  4. Rizzetto M, Ciancio A. Chronic HBV-related liver disease. Mol Aspects Med 2008;29:72-84.
  5. Jung MC, Pape GR. Immunology of hepatitis B infection. Lancet Infect Dis 2002; 2:43-50.
  6. Dengming He, Guohua Yan, Wang Y. Serum levels of interleukin-12 in various clinical states with hepatitis B virus infection. Cell Immunol 2012; 272:162-165.
  7. Megged O, Schlesinger Y. Varicella zoster infection in adults: a preventable disease. Isr Med Assoc J 2009; 11:306-307.
  8. Monaghan TM, Norton B. Varicella pneumonia in an immunocompromised inflammatory bowel disease patient. Inflamm Bowel Dis 2010;16:364-365.

Details

Primary Language

English

Subjects

-

Journal Section

-

Authors

Erkan Yula This is me

Özcan Deveci This is me

Ersin Şükrü Erden This is me

Türkan Toka Özer This is me

Alicem Tekin This is me

Melek Inci This is me

Publication Date

June 1, 2012

Submission Date

April 30, 2015

Acceptance Date

-

Published in Issue

Year 2012 Volume: 2 Number: 02

APA
Yula, E., Deveci, Ö., Erden, E. Ş., Özer, T. T., Tekin, A., & Inci, M. (2012). Pneumonic varicella in patient with inactive hepatitis B: A case report. Journal of Microbiology and Infectious Diseases, 2(02), 68-71. https://doi.org/10.5799/ahinjs.02.2012.02.0045
AMA
1.Yula E, Deveci Ö, Erden EŞ, Özer TT, Tekin A, Inci M. Pneumonic varicella in patient with inactive hepatitis B: A case report. J Microbil Infect Dis. 2012;2(02):68-71. doi:10.5799/ahinjs.02.2012.02.0045
Chicago
Yula, Erkan, Özcan Deveci, Ersin Şükrü Erden, Türkan Toka Özer, Alicem Tekin, and Melek Inci. 2012. “Pneumonic Varicella in Patient With Inactive Hepatitis B: A Case Report”. Journal of Microbiology and Infectious Diseases 2 (02): 68-71. https://doi.org/10.5799/ahinjs.02.2012.02.0045.
EndNote
Yula E, Deveci Ö, Erden EŞ, Özer TT, Tekin A, Inci M (June 1, 2012) Pneumonic varicella in patient with inactive hepatitis B: A case report. Journal of Microbiology and Infectious Diseases 2 02 68–71.
IEEE
[1]E. Yula, Ö. Deveci, E. Ş. Erden, T. T. Özer, A. Tekin, and M. Inci, “Pneumonic varicella in patient with inactive hepatitis B: A case report”, J Microbil Infect Dis, vol. 2, no. 02, pp. 68–71, June 2012, doi: 10.5799/ahinjs.02.2012.02.0045.
ISNAD
Yula, Erkan - Deveci, Özcan - Erden, Ersin Şükrü - Özer, Türkan Toka - Tekin, Alicem - Inci, Melek. “Pneumonic Varicella in Patient With Inactive Hepatitis B: A Case Report”. Journal of Microbiology and Infectious Diseases 2/02 (June 1, 2012): 68-71. https://doi.org/10.5799/ahinjs.02.2012.02.0045.
JAMA
1.Yula E, Deveci Ö, Erden EŞ, Özer TT, Tekin A, Inci M. Pneumonic varicella in patient with inactive hepatitis B: A case report. J Microbil Infect Dis. 2012;2:68–71.
MLA
Yula, Erkan, et al. “Pneumonic Varicella in Patient With Inactive Hepatitis B: A Case Report”. Journal of Microbiology and Infectious Diseases, vol. 2, no. 02, June 2012, pp. 68-71, doi:10.5799/ahinjs.02.2012.02.0045.
Vancouver
1.Erkan Yula, Özcan Deveci, Ersin Şükrü Erden, Türkan Toka Özer, Alicem Tekin, Melek Inci. Pneumonic varicella in patient with inactive hepatitis B: A case report. J Microbil Infect Dis. 2012 Jun. 1;2(02):68-71. doi:10.5799/ahinjs.02.2012.02.0045