A Case of Subcutaneous and Gastrointestinal Basidiobolomycosis in Singapore

Year 2017, , 151 - 155, 15.09.2017

Teh Yii Ean Tan Ban Hock Limin Wijaya

https://doi.org/10.5799/jmid.367574

Abstract

Entomophthoromycosis
due to Basidiobolus is a known cause of subcutaneous zygomycosis. It
occasionally causes invasive disease involving the gastrointestinal tract. We
describe a case of proven subcutaneous entomophthoromycosis, with subsequent
development of gastrointestinal basidiobolomycosis, in a 67 year old
Singaporean Chinese male. He presented with a progressively enlarging left
inguinal mass with intra-abdominal extension, causing compression of the ureters
and hydronephroses. He underwent multiple biopsies to ascertain the cause of
the mass. Workup for malignancy, bacteria, fungal, parasitic and tuberculous
infections were negative.  He developed
worsening gastrointestinal distension a year from initial presentation. Imaging
showed mucosal thickening extending from the descending colon to the rectum.
Based on the clinical presentation, he was treated as for basidiobolomycosis.
He responded poorly to treatment and passed away two months after initiation of
therapy. With the help of our counterparts in India, we proved our clinical
suspicion by polymerase chain reaction on tissue specimen. 

Keywords

Basidiobolomycosis, Entomophthoromycosis, Gastrointestinal, Inguinal mass

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