Epidemiology of Dengue Fever among clinically Suspected Febrile Patients at A Tertiary Care Center in Punjab

Year 2018, , 43 - 48, 20.06.2018

Shweta Chitkara Deepinder Chhina Veenu Gupta Rajesh Mahajan Daaman Sharma

https://doi.org/10.5799/jmid.434590

Cited By: 1

Abstract

ABSTRACT

Objective: Dengue has emerged as a major public health concern
across the globe in terms of mortality and morbidity. The clinical and
epidemiological profile of dengue infection changes from time to time. The
study was conducted to determine the prevalence of dengue infection, to study
the seasonal variation and the clinical profile in these cases.

Methods: A
prospective, observational study conducted over a period from April 2015 to
March 2016. Patients with acute febrile illness with clinical suspicion of
dengue fever admitted in the hospital were included in the study. Serological
tests like Dengue IgM and NS1 antigen ELISA were performed to confirm the
diagnosis. Serologically confirmed patients of dengue fever were studied for
their clinical presentation and lab parameters.

Results: From
a total 4732 patients tested for dengue viral infection, 1165 (24.6%) tested
positive for dengue. The most affected age group was 26-35 years (25.7%) with
male predominance. Most dengue cases were seen in the months of August to December
2015. Commonly clinical symptoms and signs were myalgia (72.4%), arthralgia
(34.4%), vomiting (50%), abdominal pain (38.6%), hepatomegaly (27.4%) and
ascites (10.8%). Lab parameters revealed leukopenia (43%) and thrombocytopenia
(93.1%) in most cases. Transaminitis was seen in 84.1% cases. Common
complications were shock (4.8%) and encephalopathy (4.8%). Hepatic failure was
seen in 3.7% of patients and renal failure in 1.8% of patients.

Conclusion: Dengue fever has a very non-specific and variable presentation.
Knowledge of local prevalence and recent outbreaks can be very helpful in
recognizing the clinical entity. J
Microbiol Infect Dis 2018; 8(2):43-48

Keywords

Dengue fever, prevalence, seasonality, clinical manifestations, tertiary care hospital

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