Research Article
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Year 2021, , 21 - 26, 15.03.2021
https://doi.org/10.5799/jmid.897184

Abstract

References

  • 1. Kennedy DW, Thaler ER. Acute vs. chronic sinusitis: etiology, management, and outcomes. Infect Dis Clin Pract 1997; 2:49-58.
  • 2. Das A, Bal A, Chakrabarti A, Panda N, Joshi K. Spectrum of fungal rhinosinusitis histopathologist’s perspective. Histopathology 2009;54(7):854-859.
  • 3. Taxy J. Paranasal Fungal Sinusitis: Contributions of Histopathology to Diagnosis. The Am J Surg Pathol 2006;30(6):713-720.
  • 4. deShazo RD, O’Brien M, Chapin K, Soto-Aguilar M, Swain R, Lyons M, et al. Criteria for the diagnosis of sinus mycetoma. J Allergy Clin Immunol 1997;99: 475-485.
  • 5. Morgan J, Warnock DW. Fungi. In: Browning GG, Burton MJ, Clarke R, Hibbert J, et al. Scott-Brown’s Otorhinolaryngology, Head and Neck Surgery. 7th ed. London: Edward Arnold; 2008; 217- 79.
  • 6. Baker RD. Mucormycosis: A new disease? JAMA 1957;163(10):805-8.
  • 7. Prayaga N, Srinivas M, Jadi L, Sudhakar K, Anil N. Clinical application of a microbiological study on chronic suppurative otitis media. Indian J Otolaryngol Head Neck Surg 2013; 2:290-4.
  • 8. Prakash M, Lakshmi K, Anuradha S, Swathi GN. Bacteriological profile and their antibiotic susceptibility pattern of cases of CSOM. Asian J Pharm Clin Res 2013; 6:210-2.
  • 9. Chander J. Fungal sinusitis. Textbook of Medical Mycology 3rd ed. New Delhi: Mehta Publishers; 2009 :480- 520.
  • 10. Browning GG, Burton MJ, Clarke R, et al. Rhinosinusitis. Scott-Brown’s Otorhinolaryngology, Head and Neck Surgery. 7th ed. London: Edward Arnold; 2008. p. 1423-1467.
  • 11. Ponikau JU, Sherris DA, Kern EB, et al. The diagnosis and incidence of allergic fungal sinusitis. Mayo Clinic Proceedings. 1999; 74:877-84.
  • 12. Manning SC, Holman M. Further evidence for allergic pathophysiology in allergic fungal sinusitis. Laryngoscope 1998; 108:1485-96.
  • 13. Micheal RC, Micheal JS, Ashbee RH, Mathews MS. Mycological profile of fungal sinusitis: an audit of specimens over a 7 year period in a tertiary care hospital in Tamil Nadu. Indian J Pathol Microbiol 2008; 51(4):493-6.
  • 14. Farhani F, Mashouf RY, Hashemian F, Esmaeli R. Antimicrobial Resistance Patters of Aerobic Organisms in Patients with Chronic Rhinosinusitis in Hamadan, Iran. Avicenna J Clin Microb Infec 2014;1(2):e18961.
  • 15. Irfan S, Farooq I, Fayaz W. Microbiological profile of patients with chronic sinusitis in Kashmir valley. JMS 2014;4(1):410-16.
  • 16. Joshi RR, Bhandary S, Khanal B, Singh RK. Fungal Maxillary sinusitis: A prospective study in a tertiary care hospital of eastern Nepal. Kathmandu Univ Med J 2007;5(2):195-198.
  • 17. Madani SA, Hashemi SA, Fazli M, Esfandiar K. Bacteriology in patients with chronic rhinosinusitis in North Iran. Jundishapur J Microbiol 2013; 6(8):e7193.
  • 18. Chakrabarti A, Sharma SC, Chander J. Epidemiology and pathogenesis of paranasal sinus mycoses. Otolaryngol Head Neck Surg 1992;107 :745-750.
  • 19. Kaur R, Lavanya S, Khurana N, Gulati A, Dhakad MS. Allergic Fungal Rhinosinusitis: A Study in a Tertiary Care Hospital in India. J Allergy (Cairo) 2016; 2016:7698173.

Non-Invasive Rhinosinusitis: Clinical and Microbiological Perspective

Year 2021, , 21 - 26, 15.03.2021
https://doi.org/10.5799/jmid.897184

Abstract

Objectives: Objectives: Fungal rhinosinusitis is one of the important healthcare problems and its incidence and prevalence are increasing over the past three decades. It affects approximately 20% of the population at some time in their lives. We aimed to identify and characterize the microorganisms causing non-invasive rhinosinusitis and to correlate the findings with the clinical profile of patients.
Methods: Clinically suspected cases of rhinosinusitis were enrolled in the study and detailed clinical history was taken. Samples like nasal mucosa, nasal crusts, scrapings / excised nasal polyps, and biopsy were collected. The specimens were processed for fungal culture. Isolates were identified as per standard protocols.
Results: A total of 74 patients clinically suspected of rhinosinusitis were enrolled in our study out of which 60.8% were males. The most common presenting complaint was nasal obstruction (91.8%) followed by nasal discharge (77%). Clinically characterizing, the most common type of non-invasive rhinosinusitis seen in our study was allergic rhinosinusitis (44.6%). KOH positivity was 45.6% and fungal culture positivity was 30.4%. The most common fungal isolate was Aspergillus flavus.
Conclusion: Continuous and periodic evaluation of the microbiological patterns of isolates is necessary to decrease the potential risk of complications by early institution of appropriate treatment. J Microbiol Infect Dis 2021; 11(1):21-26.

References

  • 1. Kennedy DW, Thaler ER. Acute vs. chronic sinusitis: etiology, management, and outcomes. Infect Dis Clin Pract 1997; 2:49-58.
  • 2. Das A, Bal A, Chakrabarti A, Panda N, Joshi K. Spectrum of fungal rhinosinusitis histopathologist’s perspective. Histopathology 2009;54(7):854-859.
  • 3. Taxy J. Paranasal Fungal Sinusitis: Contributions of Histopathology to Diagnosis. The Am J Surg Pathol 2006;30(6):713-720.
  • 4. deShazo RD, O’Brien M, Chapin K, Soto-Aguilar M, Swain R, Lyons M, et al. Criteria for the diagnosis of sinus mycetoma. J Allergy Clin Immunol 1997;99: 475-485.
  • 5. Morgan J, Warnock DW. Fungi. In: Browning GG, Burton MJ, Clarke R, Hibbert J, et al. Scott-Brown’s Otorhinolaryngology, Head and Neck Surgery. 7th ed. London: Edward Arnold; 2008; 217- 79.
  • 6. Baker RD. Mucormycosis: A new disease? JAMA 1957;163(10):805-8.
  • 7. Prayaga N, Srinivas M, Jadi L, Sudhakar K, Anil N. Clinical application of a microbiological study on chronic suppurative otitis media. Indian J Otolaryngol Head Neck Surg 2013; 2:290-4.
  • 8. Prakash M, Lakshmi K, Anuradha S, Swathi GN. Bacteriological profile and their antibiotic susceptibility pattern of cases of CSOM. Asian J Pharm Clin Res 2013; 6:210-2.
  • 9. Chander J. Fungal sinusitis. Textbook of Medical Mycology 3rd ed. New Delhi: Mehta Publishers; 2009 :480- 520.
  • 10. Browning GG, Burton MJ, Clarke R, et al. Rhinosinusitis. Scott-Brown’s Otorhinolaryngology, Head and Neck Surgery. 7th ed. London: Edward Arnold; 2008. p. 1423-1467.
  • 11. Ponikau JU, Sherris DA, Kern EB, et al. The diagnosis and incidence of allergic fungal sinusitis. Mayo Clinic Proceedings. 1999; 74:877-84.
  • 12. Manning SC, Holman M. Further evidence for allergic pathophysiology in allergic fungal sinusitis. Laryngoscope 1998; 108:1485-96.
  • 13. Micheal RC, Micheal JS, Ashbee RH, Mathews MS. Mycological profile of fungal sinusitis: an audit of specimens over a 7 year period in a tertiary care hospital in Tamil Nadu. Indian J Pathol Microbiol 2008; 51(4):493-6.
  • 14. Farhani F, Mashouf RY, Hashemian F, Esmaeli R. Antimicrobial Resistance Patters of Aerobic Organisms in Patients with Chronic Rhinosinusitis in Hamadan, Iran. Avicenna J Clin Microb Infec 2014;1(2):e18961.
  • 15. Irfan S, Farooq I, Fayaz W. Microbiological profile of patients with chronic sinusitis in Kashmir valley. JMS 2014;4(1):410-16.
  • 16. Joshi RR, Bhandary S, Khanal B, Singh RK. Fungal Maxillary sinusitis: A prospective study in a tertiary care hospital of eastern Nepal. Kathmandu Univ Med J 2007;5(2):195-198.
  • 17. Madani SA, Hashemi SA, Fazli M, Esfandiar K. Bacteriology in patients with chronic rhinosinusitis in North Iran. Jundishapur J Microbiol 2013; 6(8):e7193.
  • 18. Chakrabarti A, Sharma SC, Chander J. Epidemiology and pathogenesis of paranasal sinus mycoses. Otolaryngol Head Neck Surg 1992;107 :745-750.
  • 19. Kaur R, Lavanya S, Khurana N, Gulati A, Dhakad MS. Allergic Fungal Rhinosinusitis: A Study in a Tertiary Care Hospital in India. J Allergy (Cairo) 2016; 2016:7698173.
There are 19 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Research Article
Authors

Diljot Sandhu This is me

Veenu Gupta This is me

Deepinder Chhina This is me

Manish Munjal This is me

Publication Date March 15, 2021
Published in Issue Year 2021

Cite

APA Sandhu, D., Gupta, V., Chhina, D., Munjal, M. (2021). Non-Invasive Rhinosinusitis: Clinical and Microbiological Perspective. Journal of Microbiology and Infectious Diseases, 11(01), 21-26. https://doi.org/10.5799/jmid.897184
AMA Sandhu D, Gupta V, Chhina D, Munjal M. Non-Invasive Rhinosinusitis: Clinical and Microbiological Perspective. J Microbil Infect Dis. March 2021;11(01):21-26. doi:10.5799/jmid.897184
Chicago Sandhu, Diljot, Veenu Gupta, Deepinder Chhina, and Manish Munjal. “Non-Invasive Rhinosinusitis: Clinical and Microbiological Perspective”. Journal of Microbiology and Infectious Diseases 11, no. 01 (March 2021): 21-26. https://doi.org/10.5799/jmid.897184.
EndNote Sandhu D, Gupta V, Chhina D, Munjal M (March 1, 2021) Non-Invasive Rhinosinusitis: Clinical and Microbiological Perspective. Journal of Microbiology and Infectious Diseases 11 01 21–26.
IEEE D. Sandhu, V. Gupta, D. Chhina, and M. Munjal, “Non-Invasive Rhinosinusitis: Clinical and Microbiological Perspective”, J Microbil Infect Dis, vol. 11, no. 01, pp. 21–26, 2021, doi: 10.5799/jmid.897184.
ISNAD Sandhu, Diljot et al. “Non-Invasive Rhinosinusitis: Clinical and Microbiological Perspective”. Journal of Microbiology and Infectious Diseases 11/01 (March 2021), 21-26. https://doi.org/10.5799/jmid.897184.
JAMA Sandhu D, Gupta V, Chhina D, Munjal M. Non-Invasive Rhinosinusitis: Clinical and Microbiological Perspective. J Microbil Infect Dis. 2021;11:21–26.
MLA Sandhu, Diljot et al. “Non-Invasive Rhinosinusitis: Clinical and Microbiological Perspective”. Journal of Microbiology and Infectious Diseases, vol. 11, no. 01, 2021, pp. 21-26, doi:10.5799/jmid.897184.
Vancouver Sandhu D, Gupta V, Chhina D, Munjal M. Non-Invasive Rhinosinusitis: Clinical and Microbiological Perspective. J Microbil Infect Dis. 2021;11(01):21-6.