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Mycobacterium mucogenicum Causing Central line-related sepsis in a home parenteral nutrition patient

Year 2017, Volume: 07 Issue: 02, 93 - 97, 01.06.2017
https://doi.org/10.5799/jmid.328792

Abstract

Long-term home parenteral nutrition is associated with increased risk of line infection and subsequent sepsis. Line
infections involving rapidly growing mycobacteria are almost exclusively found in immunocompromised patients. The
authors report a case of opportunistic line-sepsis caused by Mycobacterium mucogenicum in a home parenteral
nutritional patient with overt immunocompromise. Following a prolonged clinical course and molecular sequencing
this infection was eventually diagnosed. The importance of awareness of rapidly growing mycobacteria as a
causative agent of line infection in both immunocompromised and immunocompetent patients, the need for
immediate removal of the line in such diagnosed infections, and the use of molecular techniques to identify atypical
pathogens are emphasised. J Microbiol Infect Dis 2017; 7(2): 93-97    Parenteral, Nutrition, Central Line, Mycobacterium, Sepsis, Infection

References

  • 1. Hussein Z, Landt O, Wirths B, Wellinghausen N: Detection of non-tuberculous mycobacteria in hospital water by culture and molecular methods. Int J Med Microbiol 2009; 299:281-290.
  • 2. Shehan JM, Sarma DP. Mycobacterium mucogenicum: report of a skin infection associated with etanercept. Dermatol Online J 2008, 14(1):5.
  • 3. Tse KC, Lui SL, Cheng VC, Yip TP, Lo WK. A cluster of rapidly growing mycobacterial peritoneal dialysis catheter exit-site infections. Am J Kidney Dis 2007; 50 (1):e1-5.
  • 4. Wallace RJ Jr, Silcox VA, Tsukamura M, et al. Clinical significance, biochemical features, and susceptibility patterns of sporadic isolates of the Mycobacterium chelonae-like organism. J Clin Microbiol 1993; 31(12):3231-3239.
  • 5. Fleming GA, Frangoul H, Dermody TS, Halasa N. A cord blood transplant recipient with Mycobacterium mucogenicum central venous catheter infection after infusion of tap water. Pediatr Infect Dis J 2006; 25(6):567-569.
  • 6. Covert TC, Rodgers MR, Reyes AL, Stelma GN Jr. Occurrence of nontuberculous mycobacteria in environmental samples. Appl Environ Microbiol 1999; 65 (6):2492-2496.
  • 7. Fonteyn N, Wauters G, Vandercam B, et al. Mycobacterium mucogenicum sepsis in an immunocompetent patient. J Infect 2006; 53 (3):e143-146.
  • 8. Springer B, Bottger EC, Kirschner P, Wallace RJ Jr. Phylogeny of the Mycobacterium chelonae-like organism based on partial sequencing of the 16S rRNA gene and proposal of Mycobacterium mucogenicum sp. nov. Int J Syst Bacteriol 1995; 45 (2):262-267.
  • 9. Hawkins C, Qi C, Warren J, Stosor V. Catheterrelated bloodstream infections caused by rapidly growing nontuberculous mycobacteria: a case series including rare species. Diagn Microbiol Infect Dis 2008; 61 (2):187-191.
  • 10. Brown-Elliott BA, Wallace RJ Jr. Clinical and taxonomic status of pathogenic nonpigmented or late-pigmenting rapidly growing mycobacteria. Clin Microbiol Rev 2002; 15(4):716-746.
  • 11. Kline S, Cameron S, Streifel A, et al. An outbreak of bacteremias associated with Mycobacterium mucogenicum in a hospital water supply. Infect Control Hosp Epidemiol 2004; 25(12):1042-1049.
  • 12. Schulze-Robbecke R, Feldmann C, Fischeder R, Janning B, Exner M, Wahl G. Dental units: an environmental study of sources of potentially pathogenic mycobacteria. Tuber Lung Dis 1995; 76 (4):318-323.
  • 13. Cooksey RC, Jhung MA, Yakrus MA, et al. Multiphasic approach reveals genetic diversity of environmental and patient isolates of Mycobacterium mucogenicum and Mycobacterium phocaicum associated with an outbreak of bacteremias at a Texas hospital. Appl Environ Microbiol 2008; 74 (8):2480-2487.
  • 14. Swanson DS: Central venous catheter-related infections due to nontuberculous Mycobacterium species. Pediatr Infect Dis J 1998; 17 (12):1163- 1164.
  • 15. Falkinham JO 3 rd . Growth in catheter biofilms and antibiotic resistance of Mycobacterium avium. J Med Microbiol 2007; 56 (Pt 2):250-254.
Year 2017, Volume: 07 Issue: 02, 93 - 97, 01.06.2017
https://doi.org/10.5799/jmid.328792

Abstract

References

  • 1. Hussein Z, Landt O, Wirths B, Wellinghausen N: Detection of non-tuberculous mycobacteria in hospital water by culture and molecular methods. Int J Med Microbiol 2009; 299:281-290.
  • 2. Shehan JM, Sarma DP. Mycobacterium mucogenicum: report of a skin infection associated with etanercept. Dermatol Online J 2008, 14(1):5.
  • 3. Tse KC, Lui SL, Cheng VC, Yip TP, Lo WK. A cluster of rapidly growing mycobacterial peritoneal dialysis catheter exit-site infections. Am J Kidney Dis 2007; 50 (1):e1-5.
  • 4. Wallace RJ Jr, Silcox VA, Tsukamura M, et al. Clinical significance, biochemical features, and susceptibility patterns of sporadic isolates of the Mycobacterium chelonae-like organism. J Clin Microbiol 1993; 31(12):3231-3239.
  • 5. Fleming GA, Frangoul H, Dermody TS, Halasa N. A cord blood transplant recipient with Mycobacterium mucogenicum central venous catheter infection after infusion of tap water. Pediatr Infect Dis J 2006; 25(6):567-569.
  • 6. Covert TC, Rodgers MR, Reyes AL, Stelma GN Jr. Occurrence of nontuberculous mycobacteria in environmental samples. Appl Environ Microbiol 1999; 65 (6):2492-2496.
  • 7. Fonteyn N, Wauters G, Vandercam B, et al. Mycobacterium mucogenicum sepsis in an immunocompetent patient. J Infect 2006; 53 (3):e143-146.
  • 8. Springer B, Bottger EC, Kirschner P, Wallace RJ Jr. Phylogeny of the Mycobacterium chelonae-like organism based on partial sequencing of the 16S rRNA gene and proposal of Mycobacterium mucogenicum sp. nov. Int J Syst Bacteriol 1995; 45 (2):262-267.
  • 9. Hawkins C, Qi C, Warren J, Stosor V. Catheterrelated bloodstream infections caused by rapidly growing nontuberculous mycobacteria: a case series including rare species. Diagn Microbiol Infect Dis 2008; 61 (2):187-191.
  • 10. Brown-Elliott BA, Wallace RJ Jr. Clinical and taxonomic status of pathogenic nonpigmented or late-pigmenting rapidly growing mycobacteria. Clin Microbiol Rev 2002; 15(4):716-746.
  • 11. Kline S, Cameron S, Streifel A, et al. An outbreak of bacteremias associated with Mycobacterium mucogenicum in a hospital water supply. Infect Control Hosp Epidemiol 2004; 25(12):1042-1049.
  • 12. Schulze-Robbecke R, Feldmann C, Fischeder R, Janning B, Exner M, Wahl G. Dental units: an environmental study of sources of potentially pathogenic mycobacteria. Tuber Lung Dis 1995; 76 (4):318-323.
  • 13. Cooksey RC, Jhung MA, Yakrus MA, et al. Multiphasic approach reveals genetic diversity of environmental and patient isolates of Mycobacterium mucogenicum and Mycobacterium phocaicum associated with an outbreak of bacteremias at a Texas hospital. Appl Environ Microbiol 2008; 74 (8):2480-2487.
  • 14. Swanson DS: Central venous catheter-related infections due to nontuberculous Mycobacterium species. Pediatr Infect Dis J 1998; 17 (12):1163- 1164.
  • 15. Falkinham JO 3 rd . Growth in catheter biofilms and antibiotic resistance of Mycobacterium avium. J Med Microbiol 2007; 56 (Pt 2):250-254.
There are 15 citations in total.

Details

Subjects Health Care Administration
Journal Section Case Report
Authors

Ashley Simpson William Alazawi This is me

Publication Date June 1, 2017
Published in Issue Year 2017 Volume: 07 Issue: 02

Cite

APA William Alazawi, A. S. (2017). Mycobacterium mucogenicum Causing Central line-related sepsis in a home parenteral nutrition patient. Journal of Microbiology and Infectious Diseases, 07(02), 93-97. https://doi.org/10.5799/jmid.328792
AMA William Alazawi AS. Mycobacterium mucogenicum Causing Central line-related sepsis in a home parenteral nutrition patient. J Microbil Infect Dis. June 2017;07(02):93-97. doi:10.5799/jmid.328792
Chicago William Alazawi, Ashley Simpson. “Mycobacterium Mucogenicum Causing Central Line-Related Sepsis in a Home Parenteral Nutrition Patient”. Journal of Microbiology and Infectious Diseases 07, no. 02 (June 2017): 93-97. https://doi.org/10.5799/jmid.328792.
EndNote William Alazawi AS (June 1, 2017) Mycobacterium mucogenicum Causing Central line-related sepsis in a home parenteral nutrition patient. Journal of Microbiology and Infectious Diseases 07 02 93–97.
IEEE A. S. William Alazawi, “Mycobacterium mucogenicum Causing Central line-related sepsis in a home parenteral nutrition patient”, J Microbil Infect Dis, vol. 07, no. 02, pp. 93–97, 2017, doi: 10.5799/jmid.328792.
ISNAD William Alazawi, Ashley Simpson. “Mycobacterium Mucogenicum Causing Central Line-Related Sepsis in a Home Parenteral Nutrition Patient”. Journal of Microbiology and Infectious Diseases 07/02 (June 2017), 93-97. https://doi.org/10.5799/jmid.328792.
JAMA William Alazawi AS. Mycobacterium mucogenicum Causing Central line-related sepsis in a home parenteral nutrition patient. J Microbil Infect Dis. 2017;07:93–97.
MLA William Alazawi, Ashley Simpson. “Mycobacterium Mucogenicum Causing Central Line-Related Sepsis in a Home Parenteral Nutrition Patient”. Journal of Microbiology and Infectious Diseases, vol. 07, no. 02, 2017, pp. 93-97, doi:10.5799/jmid.328792.
Vancouver William Alazawi AS. Mycobacterium mucogenicum Causing Central line-related sepsis in a home parenteral nutrition patient. J Microbil Infect Dis. 2017;07(02):93-7.