Investigation of Naturally Acquired Antibody to Haemophilus influenzae Type b Polysaccharide in China

Year 2016, Volume: 6 Issue: 4, 197 - 198, 01.12.2016

Xiumei Li

https://doi.org/10.5799/jmid.328947

Cited By: 1

Abstract

Haemophilus influenzae type b (Hib), a bacteria
pathogen, is commonly found in the oropharynx of
healthy unimmunized individuals [1]. Infections due
to Hib are a major cause of bacterial pneumonia,
meningitis, epiglottitis and septicaemia in young
children throughout the world. Hib is estimated to
cause at least 3 million cases of serious disease
every year as well as approximately 386,000 deaths
occurred in children < 5 years of age worldwide [2],
It has become a major global public health problem.
Hib conjugate vaccine, which has been widely used
in China for more than 10 years. J Microbiol Infect
Dis 2016;6(4): 197-198

Keywords

Haemophilus influenzae, Hib conjugate vaccine, China

References

• 1.Watt JP, Wolfson LJ, O’Brien KL, et al. Hib and Pneumococcal Global Burden of Disease Study Team. Burden of disease caused by Haemophilus influenzae type b in children younger than 5 years: global estimates. Lancet 2009; 374 (9693): 903-911.
• 2. WHO. WHO Position paper on Haemophilus influenzae type b conjugate vaccines. WER 2006;81(47): 445-452．
• 3. Antohyn BF, Concepcion NF, McGeary SA, et al. Immunospecificity and quantitation of an enzyme-linked immunosorbent assay for group B streptococcal antibody. J Clin Microbio 1982; l16(2): 350-354.
• 6. Wu T, Tao H, LI H, et al. Natural Immunity Antibody Level to Haemophilus Influenzae Type b Polysaccharide in Jiangsu Province. Nanjing Medical University 2007; 13(3): 267-269.
• 7. Ocaktan E, Ozyurda F, Akar N. Natural immunity to Haemophilus influenzae type Bin children of Ankara, Turkey. Pediatr Int 2004; 46(3): 280 -284.
• 8. Hutter J, Pasetti MF, Sanogo D, et al. Naturally Acquired and Conjugate Vaccine-Induced Antibody to Haemophilus influenzae Type b (Hib) Polysaccharide in Malian Children: Serological Assessment of the Hib Immunization Program in Mali. Am J Trop Med Hyg 2012; 86(6): 1026-1031.