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Hemorrhagic Fevers with Renal Syndrome Presenting with Pregnancy Interruption

Year 2017, Volume: 07 Issue: 04, 198 - 201, 01.12.2017
https://doi.org/10.5799/jmid.369267

Abstract

Hemorrhagic
fever with renal syndrome is presented with so many different clinical
symptoms. It can present mild form of the disease or the severe symptoms. We reported
two cases with HFRS, at pregnant women, ended with pregnancy interruption. Both
of them had nearly the same age, both 16 weeks pregnant. They presented with
fever, malaise, muscle pain and headache. They were febrile when presented at
the hospital, hypotensive, hyperemia on the face. They complained about
oligo-anuria too. One of them continued to be hypotension, despite the
supportive therapy she had an abortion after 8 hours. The other patient had the
abortion on the 4th day of hospitalization. The diagnose was set
based on the clinical, epidemiological findings and the serological positive
confirmation for IgM Hantavirus by enzyme-linked immunosorbent assay and immunofluorescence
assay IFA.



The
abortion is a rare complication of HFRS in pregnancy. The symptoms are not
specific. Early diagnosis and appropriate management are necessary to improve
the maternal and fetal outcome. J
Microbiol Infect Dis 2017; 7(4):198-201

References

  • 1. Berk H, Öztoprak N. Hemorrhagic fever with renal syndrome (Hantaviruses). J Microbiol Infect Dis 2014, 4(5). 2. Županc TA, Korva M, Markotić A. HFRS and hantaviruses in the Balkans/South-East Europe. Virus Research 2014, 187:27-33. 3. Kostakoglu U, Yılmaz G, Volkan S, Sökel SK, Kaya S, Köksal I. Evaluation of clinical and laboratory predictors of fatality in patients with Hantavirus infection. J Microbiol Infect Dis 2012, 2(04). 4. Puca E, Pilaca A, Pipero P, et al. A short review of hemorrhagic fever with renal syndrome and it's extrarenal complications. J Microbiol Infect Dis 2014, 4(5). 5. Emmerich P, Müller N, Heinemann P, et al Human Dobrava-Belgrade hantavirus infection, Kosovo. J Clin Virol 2014, 61(3):439-441. 6. Mustonen J, Vaheri A, Clement J. Third international conference on haemorrhagic fever with renal syndrome (HFRS) and hantaviruses. Nephrology Dialysis Transplantation 1996, 11(4):730-733. 7. Kim B-N, Choi B-D. Hemorrhagic fever with renal syndrome complicated with pregnancy: a case report. The Korean journal of internal medicine 2006, 21(2):150. 8. Hofmann J, Führer A, Bolz M, et al. Hantavirus infections by Puumala or Dobrava-Belgrade virus in pregnant women. Journal of Clinical Virology 2012, 55(3):266-269. 9. Howard MJ, Doyle TJ, Koster FT, et al. Hantavirus pulmonary syndrome in pregnancy. Clin Infect Dis 1999, 29(6):1538-1544. 10. Rogozi E, Bego F, Papa A, Mersini K, Bino S. Distribution and ecology of small mammals in Albania. International journal of environmental health research 2013, 23(3):258-268. 11. Puca E, Pilaca A, Pipero P, et al. Hemorrhagic fever with renal syndrome complicated by orchitis. Virologica Sinica 2011, 26(4):285. 12. Du H, Li J, Yu H-T, et al. Early indicators of severity and construction of a risk model for prognosis based upon laboratory parameters in patients with hemorrhagic fever with renal syndrome. Clinical Chemistry and Laboratory Medicine (CCLM) 2014, 52(11):1667-1675. 13. Ozturk B, Tutuncu E, Kuscu F, Gurbuz Y, Sencan I, Tuzun H. Evaluation of factors predictive of the prognosis in Crimean-Congo hemorrhagic fever: new suggestions. Int J Infect Dis 2012, 16(2):e89-e93.
Year 2017, Volume: 07 Issue: 04, 198 - 201, 01.12.2017
https://doi.org/10.5799/jmid.369267

Abstract

References

  • 1. Berk H, Öztoprak N. Hemorrhagic fever with renal syndrome (Hantaviruses). J Microbiol Infect Dis 2014, 4(5). 2. Županc TA, Korva M, Markotić A. HFRS and hantaviruses in the Balkans/South-East Europe. Virus Research 2014, 187:27-33. 3. Kostakoglu U, Yılmaz G, Volkan S, Sökel SK, Kaya S, Köksal I. Evaluation of clinical and laboratory predictors of fatality in patients with Hantavirus infection. J Microbiol Infect Dis 2012, 2(04). 4. Puca E, Pilaca A, Pipero P, et al. A short review of hemorrhagic fever with renal syndrome and it's extrarenal complications. J Microbiol Infect Dis 2014, 4(5). 5. Emmerich P, Müller N, Heinemann P, et al Human Dobrava-Belgrade hantavirus infection, Kosovo. J Clin Virol 2014, 61(3):439-441. 6. Mustonen J, Vaheri A, Clement J. Third international conference on haemorrhagic fever with renal syndrome (HFRS) and hantaviruses. Nephrology Dialysis Transplantation 1996, 11(4):730-733. 7. Kim B-N, Choi B-D. Hemorrhagic fever with renal syndrome complicated with pregnancy: a case report. The Korean journal of internal medicine 2006, 21(2):150. 8. Hofmann J, Führer A, Bolz M, et al. Hantavirus infections by Puumala or Dobrava-Belgrade virus in pregnant women. Journal of Clinical Virology 2012, 55(3):266-269. 9. Howard MJ, Doyle TJ, Koster FT, et al. Hantavirus pulmonary syndrome in pregnancy. Clin Infect Dis 1999, 29(6):1538-1544. 10. Rogozi E, Bego F, Papa A, Mersini K, Bino S. Distribution and ecology of small mammals in Albania. International journal of environmental health research 2013, 23(3):258-268. 11. Puca E, Pilaca A, Pipero P, et al. Hemorrhagic fever with renal syndrome complicated by orchitis. Virologica Sinica 2011, 26(4):285. 12. Du H, Li J, Yu H-T, et al. Early indicators of severity and construction of a risk model for prognosis based upon laboratory parameters in patients with hemorrhagic fever with renal syndrome. Clinical Chemistry and Laboratory Medicine (CCLM) 2014, 52(11):1667-1675. 13. Ozturk B, Tutuncu E, Kuscu F, Gurbuz Y, Sencan I, Tuzun H. Evaluation of factors predictive of the prognosis in Crimean-Congo hemorrhagic fever: new suggestions. Int J Infect Dis 2012, 16(2):e89-e93.
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Details

Journal Section Case Report
Authors

Elda Qyra This is me

Edmond Puca This is me

Arjan Harxhi This is me

Majlinda Kote This is me

Pellumb Pipero This is me

Publication Date December 1, 2017
Published in Issue Year 2017 Volume: 07 Issue: 04

Cite

APA Qyra, E., Puca, E., Harxhi, A., Kote, M., et al. (2017). Hemorrhagic Fevers with Renal Syndrome Presenting with Pregnancy Interruption. Journal of Microbiology and Infectious Diseases, 07(04), 198-201. https://doi.org/10.5799/jmid.369267
AMA Qyra E, Puca E, Harxhi A, Kote M, Pipero P. Hemorrhagic Fevers with Renal Syndrome Presenting with Pregnancy Interruption. J Microbil Infect Dis. December 2017;07(04):198-201. doi:10.5799/jmid.369267
Chicago Qyra, Elda, Edmond Puca, Arjan Harxhi, Majlinda Kote, and Pellumb Pipero. “Hemorrhagic Fevers With Renal Syndrome Presenting With Pregnancy Interruption”. Journal of Microbiology and Infectious Diseases 07, no. 04 (December 2017): 198-201. https://doi.org/10.5799/jmid.369267.
EndNote Qyra E, Puca E, Harxhi A, Kote M, Pipero P (December 1, 2017) Hemorrhagic Fevers with Renal Syndrome Presenting with Pregnancy Interruption. Journal of Microbiology and Infectious Diseases 07 04 198–201.
IEEE E. Qyra, E. Puca, A. Harxhi, M. Kote, and P. Pipero, “Hemorrhagic Fevers with Renal Syndrome Presenting with Pregnancy Interruption”, J Microbil Infect Dis, vol. 07, no. 04, pp. 198–201, 2017, doi: 10.5799/jmid.369267.
ISNAD Qyra, Elda et al. “Hemorrhagic Fevers With Renal Syndrome Presenting With Pregnancy Interruption”. Journal of Microbiology and Infectious Diseases 07/04 (December 2017), 198-201. https://doi.org/10.5799/jmid.369267.
JAMA Qyra E, Puca E, Harxhi A, Kote M, Pipero P. Hemorrhagic Fevers with Renal Syndrome Presenting with Pregnancy Interruption. J Microbil Infect Dis. 2017;07:198–201.
MLA Qyra, Elda et al. “Hemorrhagic Fevers With Renal Syndrome Presenting With Pregnancy Interruption”. Journal of Microbiology and Infectious Diseases, vol. 07, no. 04, 2017, pp. 198-01, doi:10.5799/jmid.369267.
Vancouver Qyra E, Puca E, Harxhi A, Kote M, Pipero P. Hemorrhagic Fevers with Renal Syndrome Presenting with Pregnancy Interruption. J Microbil Infect Dis. 2017;07(04):198-201.