Profile of Person Affected by Leprosy with Clinical Relapse among in High Endemic State of India

Year 2018, Volume: 08 Issue: 03, 103 - 107, 15.09.2018

Sunil Vilasrao Gitte Chaitanya Nigam Ashish B. Chakraborty Krishnamurty Kamble Mukesh Soni Rupam Gahlot

https://doi.org/10.5799/jmid.458458

Cited By: 1

Abstract

Objective: Relapse is not an unusual phenomenon in leprosy, there
are many predisposing factors which may lead to occurrence of relapse; some of
these include the presence of persistent bacilli, drug monotherapy, inadequate
or irregular therapy. Patients usually presents with presence of multiple skin
lesions and/or thickened nerves, reason for early relapse is probably bacillary
persistence due to inadequate treatment and for late relapse due to or
re-infection. The objectives of this study are to assess various clinico-epidemiological
factors associated with the occurrence of relapses in leprosy patients.

Methods: A
hospital record based retrospective follow-up study has been performed and 117
relapse cases of leprosy were included. Leprosy relapse cases presented in the
study hospital were interviewed using a predesigned and pretested preformed.
Each patient was subjected to clinical, bacteriological and disability
assessments for diagnosis of relapse and followed until the completion of multi
drug therapy.

Results: During
a study period, relapse was seen more in male as compared to female. The
duration between cessation of treatment and re-appearance of new lesions varied
from 1 to 33 years. Disability proportion was high among MB patients.

Conclusion: Relapse in leprosy should be thoroughly examined and
looked for drug resistance. J Microbiol
Infect Dis 2018; 8(3):103-107

Keywords

Drug resistance, Disability, Leprosy, MDT, Multibacillary, Paucibacillary, Relapse

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