Year 2019, Volume 09 , Issue 03, Pages 133 - 136 2019-09-15

A vasculonecrotic Type 2 Lepra Reaction Mimicking Lucio Phenomenon

Shreya Pradipbhai Somani [1] , Hita Hemant [2] , Mehta Milan [3] , Dilipkumar Jhavar [4] , Bhavesh N. Astik [5] , Rahul Lakhotia [6]


Multibacillary, lepromatous or borderline leprosy patients may present two types Vasculonecrotic reactions: Erythema Nodosum Leprosum (ENL) with vasculitis and Lucio Phenomenon. ENL is Type 2 Lepra Reaction while Lucio Phenomenon commonly seen in nonnodular diffuse leprosy patients, mainly reported from Mexico. Here we reported a case of 20 year old male, RFT (Relief From Treatment) leprosy patient presented with fever, malaise, joint pain, edema over hands and feet and red tender elevated nodules. Interestingly, within 3 days of admission he developed multiple vesicular erythema multiforme like eruption on chest, back and upper extremity, which broken down to form necrotic ulcer in following 4 days. Biopsy showed leucocytoclastic vasculitis and fibrin deposition in vessel walls. Furthermore, USG of both ulnar nerves showed thickening. These clinical and histopathological features helped us to arrive at the diagnosis of the ENL with vasculonecrotic phenomenon. J Microbiol Infect Dis 2019; 9(3):133-136.
Lepra reaction, vasculonecrotic phenomenon, ENL, Lucio Phenomenon
  • 1. Belgaumkumar VA, Chavan RB, Salunle AS, Chirame SS. De-novo Ulceration - Rare Lazarine leprosy- like presentation of Borderline Lepromatous Hansen’s Disease. Indian J Lepr 2018; 90:69-73 2. Kahawita IP; Walker SL, Lockwood DNJ. Leprosy type 1 reactions and erythema nodosum Leprosum. An Bras Dermatol 2008; 83 (1):75-82. 3. Ranugha P, Chandrashekhar L, Kumari R, Thappa DM, Badhe B. Is It Lucio Phenomenon or Necrotic Nodosum Leprosum? Indian J Dermatol. 2013; 58(2):160. 4. Voorend CG, Post EB. A Systematic Review on the Epidemiological Data of Erythema Nodosum Leprosum, a Type 2 Leprosy Reaction. PLoS Negl Trop Dis 2013 (10): e2440. 5. Bharti AH, Patel P. A Case of Hansen's Disease Presenting with Lucio Phenomenon from Gujarat, India. Indian J Lepr 2017, 89: 217-224. 6. Fogangolo L; de Souza EM; Cintra ML, Vehlo PENF. Vasculonecrotic reactions in leprosy. Braz J Infect Dis. 2007; 11(3):378-382.
Primary Language en
Journal Section Case Report
Authors

Author: Shreya Pradipbhai Somani

Author: Hita Hemant (Primary Author)
Institution: Department of Dermatology, Government Medical College, Bhavnagar, Gujarat, India
Country: India


Author: Mehta Milan

Author: Dilipkumar Jhavar

Author: Bhavesh N. Astik

Author: Rahul Lakhotia

Dates

Publication Date : September 15, 2019

Bibtex @case report { jmid614266, journal = {Journal of Microbiology and Infectious Diseases}, issn = {2146-3158}, eissn = {2146-9369}, address = {}, publisher = {Sağlık Araştırmaları Derneği}, year = {2019}, volume = {09}, pages = {133 - 136}, doi = {10.5799/jmid.614266}, title = {A vasculonecrotic Type 2 Lepra Reaction Mimicking Lucio Phenomenon}, key = {cite}, author = {Somani, Shreya Pradipbhai and Hemant, Hita and Milan, Mehta and Jhavar, Dilipkumar and Astik, Bhavesh N. and Lakhotia, Rahul} }
APA Somani, S , Hemant, H , Milan, M , Jhavar, D , Astik, B , Lakhotia, R . (2019). A vasculonecrotic Type 2 Lepra Reaction Mimicking Lucio Phenomenon. Journal of Microbiology and Infectious Diseases , 09 (03) , 133-136 . DOI: 10.5799/jmid.614266
MLA Somani, S , Hemant, H , Milan, M , Jhavar, D , Astik, B , Lakhotia, R . "A vasculonecrotic Type 2 Lepra Reaction Mimicking Lucio Phenomenon". Journal of Microbiology and Infectious Diseases 09 (2019 ): 133-136 <https://dergipark.org.tr/en/pub/jmid/issue/48485/614266>
Chicago Somani, S , Hemant, H , Milan, M , Jhavar, D , Astik, B , Lakhotia, R . "A vasculonecrotic Type 2 Lepra Reaction Mimicking Lucio Phenomenon". Journal of Microbiology and Infectious Diseases 09 (2019 ): 133-136
RIS TY - JOUR T1 - A vasculonecrotic Type 2 Lepra Reaction Mimicking Lucio Phenomenon AU - Shreya Pradipbhai Somani , Hita Hemant , Mehta Milan , Dilipkumar Jhavar , Bhavesh N. Astik , Rahul Lakhotia Y1 - 2019 PY - 2019 N1 - doi: 10.5799/jmid.614266 DO - 10.5799/jmid.614266 T2 - Journal of Microbiology and Infectious Diseases JF - Journal JO - JOR SP - 133 EP - 136 VL - 09 IS - 03 SN - 2146-3158-2146-9369 M3 - doi: 10.5799/jmid.614266 UR - https://doi.org/10.5799/jmid.614266 Y2 - 2019 ER -
EndNote %0 Journal of Microbiology and Infectious Diseases A vasculonecrotic Type 2 Lepra Reaction Mimicking Lucio Phenomenon %A Shreya Pradipbhai Somani , Hita Hemant , Mehta Milan , Dilipkumar Jhavar , Bhavesh N. Astik , Rahul Lakhotia %T A vasculonecrotic Type 2 Lepra Reaction Mimicking Lucio Phenomenon %D 2019 %J Journal of Microbiology and Infectious Diseases %P 2146-3158-2146-9369 %V 09 %N 03 %R doi: 10.5799/jmid.614266 %U 10.5799/jmid.614266
ISNAD Somani, Shreya Pradipbhai , Hemant, Hita , Milan, Mehta , Jhavar, Dilipkumar , Astik, Bhavesh N. , Lakhotia, Rahul . "A vasculonecrotic Type 2 Lepra Reaction Mimicking Lucio Phenomenon". Journal of Microbiology and Infectious Diseases 09 / 03 (September 2019): 133-136 . https://doi.org/10.5799/jmid.614266
AMA Somani S , Hemant H , Milan M , Jhavar D , Astik B , Lakhotia R . A vasculonecrotic Type 2 Lepra Reaction Mimicking Lucio Phenomenon. J Microbil Infect Dis. 2019; 09(03): 133-136.
Vancouver Somani S , Hemant H , Milan M , Jhavar D , Astik B , Lakhotia R . A vasculonecrotic Type 2 Lepra Reaction Mimicking Lucio Phenomenon. Journal of Microbiology and Infectious Diseases. 2019; 09(03): 136-133.