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Successful salvage treatment of Lecythophora mutabilis keratitis with topical voriconazole

Year 2011, Volume: 1 Issue: 02, 75 - 77, 01.06.2011
https://doi.org/10.5799/ahinjs.02.2011.02.0018

Abstract

Fungal keratitis is an important ophthalmic problem in the developing world. Filamentous fungi are the most frequently reported pathogens in fungal keratitis. This report aimed to present a case with Lecythophora mutabilis keratitis that treatment failure was seen with topical and systemic amphotericin B lipid complex. Then she was treated successfully topical voriconazole.

References

  • Al-Badriyeh D, Neoh CF, Stewart K, Kong DC.. Clinical utility of voriconazole eye drops in ophthalmic fungal keratitis. Clin Ophthalmol 2010; 4: 391-405.
  • Hariprasad SM, Mieler WF, Lin TK, Sponsel WE, Graybill JR. Voriconazole in the treatment of fungal eye infections: A review of current literature. Br J Ophthalmol 2008; 92:871– 878.
  • Fintelmann RE, Gilmer W, Bloomer MM, Jeng BH. Recur- rent Lecythophora mutabilis keratitis and endophthalmitis after deep anterior lamellar keratoplasty. Arch Ophthalmol. 2011;129:108-110.
  • Marcus DM, Hull DS, Rubin RM, Newman CL. Lecythophora mutabilis endophthalmitis after long-term corneal cyanoacry- late. Retina. 1999;19:351-353.
  • Scott IU, Cruz-Villegas V, Flynn HW Jr, Miller D. Delayed-on- set, bleb-associated endophthalmitis caused by Lecythopho- ra mutabilis. Am J Ophthalmol 2004;137:583-585.
  • Riddell J, Comer GM, Kauffman CA. Treatment of endogenous fungal endophthalmitis: focus on new antifungal agents. Clin Infect Dis 2011; 52:648-653.
  • Goldblum D, Frueh BE, Zimmerli S, Böhnke M. Treatment of post-keratitis Fusarium endophthalmitis with amphotericin B lipid complex. Cornea 2000; 19:853-857.
  • Virata SR, Kylstra JA, Brown JC, Wohl DA, Cohen MS. Wors- ening of endogenous Candida albicans endophthalmitis dur- ing therapy with intravenous lipid complex amphotericin B. Clin Infect Dis 1999; 28:1177-1178.
  • Al-Badriyeh D, Leung L, Davies GE, Stewart K, Kong D. Suc- cessful use of topical voriconazole 1% alone as first-line antifungal therapy against Candida albicans keratitis. Ann Pharmacother 2009;43: 2103-2107.
  • Dupuis A, Tournier N, Le Moal G, Venisse N. Preparation and stability of voriconazole eye drop solution. Antimicrob Agents Chemother. 2009; 53:798–799.
  • Lau D, Ferdinands M, Leung L, et al. Penetration of voricon- azole 1% eyedrops into human aqueous humor. A prospec- tive open label study. Arch Ophthalmol 2008; 126: 343-346.

Successful salvage treatment of Lecythophora mutabilis keratitis with topical voriconazole

Year 2011, Volume: 1 Issue: 02, 75 - 77, 01.06.2011
https://doi.org/10.5799/ahinjs.02.2011.02.0018

Abstract

References

  • Al-Badriyeh D, Neoh CF, Stewart K, Kong DC.. Clinical utility of voriconazole eye drops in ophthalmic fungal keratitis. Clin Ophthalmol 2010; 4: 391-405.
  • Hariprasad SM, Mieler WF, Lin TK, Sponsel WE, Graybill JR. Voriconazole in the treatment of fungal eye infections: A review of current literature. Br J Ophthalmol 2008; 92:871– 878.
  • Fintelmann RE, Gilmer W, Bloomer MM, Jeng BH. Recur- rent Lecythophora mutabilis keratitis and endophthalmitis after deep anterior lamellar keratoplasty. Arch Ophthalmol. 2011;129:108-110.
  • Marcus DM, Hull DS, Rubin RM, Newman CL. Lecythophora mutabilis endophthalmitis after long-term corneal cyanoacry- late. Retina. 1999;19:351-353.
  • Scott IU, Cruz-Villegas V, Flynn HW Jr, Miller D. Delayed-on- set, bleb-associated endophthalmitis caused by Lecythopho- ra mutabilis. Am J Ophthalmol 2004;137:583-585.
  • Riddell J, Comer GM, Kauffman CA. Treatment of endogenous fungal endophthalmitis: focus on new antifungal agents. Clin Infect Dis 2011; 52:648-653.
  • Goldblum D, Frueh BE, Zimmerli S, Böhnke M. Treatment of post-keratitis Fusarium endophthalmitis with amphotericin B lipid complex. Cornea 2000; 19:853-857.
  • Virata SR, Kylstra JA, Brown JC, Wohl DA, Cohen MS. Wors- ening of endogenous Candida albicans endophthalmitis dur- ing therapy with intravenous lipid complex amphotericin B. Clin Infect Dis 1999; 28:1177-1178.
  • Al-Badriyeh D, Leung L, Davies GE, Stewart K, Kong D. Suc- cessful use of topical voriconazole 1% alone as first-line antifungal therapy against Candida albicans keratitis. Ann Pharmacother 2009;43: 2103-2107.
  • Dupuis A, Tournier N, Le Moal G, Venisse N. Preparation and stability of voriconazole eye drop solution. Antimicrob Agents Chemother. 2009; 53:798–799.
  • Lau D, Ferdinands M, Leung L, et al. Penetration of voricon- azole 1% eyedrops into human aqueous humor. A prospec- tive open label study. Arch Ophthalmol 2008; 126: 343-346.
There are 11 citations in total.

Details

Primary Language English
Journal Section Case Report
Authors

Orçun Pehlivan This is me

Şebnem Çalık This is me

Bora Yüksel This is me

Publication Date June 1, 2011
Published in Issue Year 2011 Volume: 1 Issue: 02

Cite

APA Pehlivan, O., Çalık, Ş., & Yüksel, B. (2011). Successful salvage treatment of Lecythophora mutabilis keratitis with topical voriconazole. Journal of Microbiology and Infectious Diseases, 1(02), 75-77. https://doi.org/10.5799/ahinjs.02.2011.02.0018
AMA Pehlivan O, Çalık Ş, Yüksel B. Successful salvage treatment of Lecythophora mutabilis keratitis with topical voriconazole. J Microbil Infect Dis. June 2011;1(02):75-77. doi:10.5799/ahinjs.02.2011.02.0018
Chicago Pehlivan, Orçun, Şebnem Çalık, and Bora Yüksel. “Successful Salvage Treatment of Lecythophora Mutabilis Keratitis With Topical Voriconazole”. Journal of Microbiology and Infectious Diseases 1, no. 02 (June 2011): 75-77. https://doi.org/10.5799/ahinjs.02.2011.02.0018.
EndNote Pehlivan O, Çalık Ş, Yüksel B (June 1, 2011) Successful salvage treatment of Lecythophora mutabilis keratitis with topical voriconazole. Journal of Microbiology and Infectious Diseases 1 02 75–77.
IEEE O. Pehlivan, Ş. Çalık, and B. Yüksel, “Successful salvage treatment of Lecythophora mutabilis keratitis with topical voriconazole”, J Microbil Infect Dis, vol. 1, no. 02, pp. 75–77, 2011, doi: 10.5799/ahinjs.02.2011.02.0018.
ISNAD Pehlivan, Orçun et al. “Successful Salvage Treatment of Lecythophora Mutabilis Keratitis With Topical Voriconazole”. Journal of Microbiology and Infectious Diseases 1/02 (June 2011), 75-77. https://doi.org/10.5799/ahinjs.02.2011.02.0018.
JAMA Pehlivan O, Çalık Ş, Yüksel B. Successful salvage treatment of Lecythophora mutabilis keratitis with topical voriconazole. J Microbil Infect Dis. 2011;1:75–77.
MLA Pehlivan, Orçun et al. “Successful Salvage Treatment of Lecythophora Mutabilis Keratitis With Topical Voriconazole”. Journal of Microbiology and Infectious Diseases, vol. 1, no. 02, 2011, pp. 75-77, doi:10.5799/ahinjs.02.2011.02.0018.
Vancouver Pehlivan O, Çalık Ş, Yüksel B. Successful salvage treatment of Lecythophora mutabilis keratitis with topical voriconazole. J Microbil Infect Dis. 2011;1(02):75-7.