BibTex RIS Cite

Fungal endocarditis with right ventricular candidal mycetoma in a premature neonate

Year 2015, Volume: 5 Issue: 3, 142 - 145, 06.02.2016

Jayashree Purkayastha Leslie Lewis Ramesh Bhat Y Morakhia Jwalit V Ranjan Shetty K Muhammad Najih L

https://doi.org/10.5799/ahijs.02.2015.03.0194
Cited By: 1

Abstract

Fungal mycetoma or endocarditis is rare in premature neonates and it is often associated with high mortality. In the majority of the cases diagnosis is made postmortem. Here we report a 30-week-old preterm neonate who developed Candida albicans blood stream infection complicated by endocarditis and subsequent mycetoma. Initially, this neonate had Klebsiella sepsis requiring multiple antibiotic courses. A peripherally inserted central venous catheter was used to give total parenteral nutrition. On day 24 of life, he developed candidemia, treated with 14 day course of fluconazole and shown improvement. Further, on day 60 of life he developed cholestasis, deranged liver function tests and persistent thrombocytopenia along with apnea, bradycardia and desaturations. Blood culture again grew again C. albicans. Echocardiography showed large fungal vegetation on tricuspid valve with a mycetoma filling the right ventricle. He was treated with intravenous amphotericin B, fluconazole and supportive measures, but he deteriorated and succumbed after two weeks. J Microbiol Infect Dis 2015;5(3): 142-145

Key words: Prematureneonate, candida sepsis, endocarditis, mycetoma

Keywords

Prematureneonate candida sepsis endocarditis mycetoma

References

  • Millar BC, Jugo J, Moore JE. Fungal endocarditis in neonates and children. Pediatr Cardiol 2005;26:517-536.
  • Sharma J, Nagaraj A, Allapathy D, et al. Fungal endocarditis
  • in a prematureinfant complicated by a right atrial mycetoma and IVC thrombosis. Images Pediatr Cardiol 2009;11:6-11.
  • Noyola DE, Fernandes M, Moylett E, Baker CJ. Ophthalmologic,
  • visceral and cardiac involvement in neonates with candidemia.Clin Infect Dis 2001;32:1018-1032.
  • Citak M, Rees A, Mavroudis C. Surgical management of infective
  • endocarditis in children. Ann Thorac Surg 1992;54:755-760.
  • Levy I, Shalit I, Birk E, et al. Candida endocarditis in neonates:
  • report of five cases and review of the literature. Mycoses 2006;49:4.
  • Emilio M, Jose M, Juan C, Guarro Josep G. Fungal endocarditis
  • in Premature Infant. Case Report and Review. Clin Infect Dis. 1996;22:366-368.
  • Pappas GP, Kauffman AC, Andes D, et al. Clinical Practice
  • Guidelines for the management of Candidiasis: 2009 Updateby the Infectious Diseases Society of America. Clin Infect Dis 2009;48:503-535.

-

Year 2015, Volume: 5 Issue: 3, 142 - 145, 06.02.2016

Jayashree Purkayastha Leslie Lewis Ramesh Bhat Y Morakhia Jwalit V Ranjan Shetty K Muhammad Najih L

https://doi.org/10.5799/ahijs.02.2015.03.0194
Cited By: 1

Abstract

Prematür yenidoğanlarda mantar miçetoma nadirdir ve sıklıkla mortaliteyle sonuçlanır. Olguların çoğunda tanı postmortem konulur. Burada Candida albicans ile kan dolaşımı enfeksiyonu gelişen, ardından endokardit ve miçetoma ile komplike olan 30 haftalık preterm bir yenidoğan olgusunu sunduk. Bu yenidoğanın başlangıçta çoklu antibiyotik kullanmayı gerektiren Klebsiella sepsisi vardı. Total parenteral beslenme için periferden konulan bir santral venöz kateter kullanıldı. Doğumdan sonraki 24. günde kandidemi gelişti, 14 gün süreyle flukonazol ile tedavi edildi ve iyileşme gösterdi. Daha sonra 60. günde kolestaz gelişti ve bozulan karaciğer fonksiyon testleri ve sürekli trombositopeni ile birlikte apne, bradikardi ve satürasyon bozuklukları ortaya çıktı. Kan kültüründe tekrar C. albicans üredi. Ekokardiyografide sağ ventrikülü dolduran bir miçetoma ile triküspid kapak üzerinde büyük bir mantar vejetasyonu görüldü. Damar yoluyla amfoterisin B ve flukonazol tedavisi yanında diğer gereken tıbbı destekler yapıldı ancak hastanın genel durumu bozularak iki hafta sonra kaybedildi

Keywords

Prematür yenidoğan candida sepsisi endokardit miçetoma

References

  • Millar BC, Jugo J, Moore JE. Fungal endocarditis in neonates and children. Pediatr Cardiol 2005;26:517-536.
  • Sharma J, Nagaraj A, Allapathy D, et al. Fungal endocarditis
  • in a prematureinfant complicated by a right atrial mycetoma and IVC thrombosis. Images Pediatr Cardiol 2009;11:6-11.
  • Noyola DE, Fernandes M, Moylett E, Baker CJ. Ophthalmologic,
  • visceral and cardiac involvement in neonates with candidemia.Clin Infect Dis 2001;32:1018-1032.
  • Citak M, Rees A, Mavroudis C. Surgical management of infective
  • endocarditis in children. Ann Thorac Surg 1992;54:755-760.
  • Levy I, Shalit I, Birk E, et al. Candida endocarditis in neonates:
  • report of five cases and review of the literature. Mycoses 2006;49:4.
  • Emilio M, Jose M, Juan C, Guarro Josep G. Fungal endocarditis
  • in Premature Infant. Case Report and Review. Clin Infect Dis. 1996;22:366-368.
  • Pappas GP, Kauffman AC, Andes D, et al. Clinical Practice
  • Guidelines for the management of Candidiasis: 2009 Updateby the Infectious Diseases Society of America. Clin Infect Dis 2009;48:503-535.
There are 13 citations in total.

Details

Primary Language English
Journal Section Case Report
Authors

Jayashree Purkayastha This is me

Leslie Lewis This is me

Ramesh Bhat Y This is me

Morakhia Jwalit V This is me

Ranjan Shetty K This is me

Muhammad Najih L This is me

Publication Date February 6, 2016
Published in Issue Year 2015 Volume: 5 Issue: 3

Cite

APA Purkayastha, J., Lewis, L., Bhat Y, R., Jwalit V, M., et al. (2016). Fungal endocarditis with right ventricular candidal mycetoma in a premature neonate. Journal of Microbiology and Infectious Diseases, 5(3), 142-145. https://doi.org/10.5799/ahijs.02.2015.03.0194
AMA Purkayastha J, Lewis L, Bhat Y R, Jwalit V M, Shetty K R, Najih L M. Fungal endocarditis with right ventricular candidal mycetoma in a premature neonate. J Microbil Infect Dis. February 2016;5(3):142-145. doi:10.5799/ahijs.02.2015.03.0194
Chicago Purkayastha, Jayashree, Leslie Lewis, Ramesh Bhat Y, Morakhia Jwalit V, Ranjan Shetty K, and Muhammad Najih L. “Fungal Endocarditis With Right Ventricular Candidal Mycetoma in a Premature Neonate”. Journal of Microbiology and Infectious Diseases 5, no. 3 (February 2016): 142-45. https://doi.org/10.5799/ahijs.02.2015.03.0194.
EndNote Purkayastha J, Lewis L, Bhat Y R, Jwalit V M, Shetty K R, Najih L M (February 1, 2016) Fungal endocarditis with right ventricular candidal mycetoma in a premature neonate. Journal of Microbiology and Infectious Diseases 5 3 142–145.
IEEE J. Purkayastha, L. Lewis, R. Bhat Y, M. Jwalit V, R. Shetty K, and M. Najih L, “Fungal endocarditis with right ventricular candidal mycetoma in a premature neonate”, J Microbil Infect Dis, vol. 5, no. 3, pp. 142–145, 2016, doi: 10.5799/ahijs.02.2015.03.0194.
ISNAD Purkayastha, Jayashree et al. “Fungal Endocarditis With Right Ventricular Candidal Mycetoma in a Premature Neonate”. Journal of Microbiology and Infectious Diseases 5/3 (February 2016), 142-145. https://doi.org/10.5799/ahijs.02.2015.03.0194.
JAMA Purkayastha J, Lewis L, Bhat Y R, Jwalit V M, Shetty K R, Najih L M. Fungal endocarditis with right ventricular candidal mycetoma in a premature neonate. J Microbil Infect Dis. 2016;5:142–145.
MLA Purkayastha, Jayashree et al. “Fungal Endocarditis With Right Ventricular Candidal Mycetoma in a Premature Neonate”. Journal of Microbiology and Infectious Diseases, vol. 5, no. 3, 2016, pp. 142-5, doi:10.5799/ahijs.02.2015.03.0194.
Vancouver Purkayastha J, Lewis L, Bhat Y R, Jwalit V M, Shetty K R, Najih L M. Fungal endocarditis with right ventricular candidal mycetoma in a premature neonate. J Microbil Infect Dis. 2016;5(3):142-5.

Cited By

White Grain Eumycetoma due to Aspergillus flavus in Infancy: A Rare Case Report from Assam
Journal of Pure and Applied Microbiology
Lakshyasri Baishya
https://doi.org/10.22207/JPAM.11.2.38