Research Article

The Relationship Between De Ritis Rate and Fatty Liver in Covid-19 Patients

Volume: 5 Number: 1 June 30, 2023
TR

The Relationship Between De Ritis Rate and Fatty Liver in Covid-19 Patients

Abstract

Objective: This study aimed to comparatively examine the relationship between the rate of De Ritis and fatty liver in COVID-19 patients. Method: A total of 182 COVID-19 patients, 133 men and 49 women, were included in the study. The study was carried out on patients with a definitive diagnosis of COVID-19 between May 1, 2020 and March 29, 2021. This study is retrospective and the data were obtained from the hospital information management system. The diagnosis of COVID-19 in the included patients was made by a real-time polymerase chain reaction and computed tomography lung scanning. In COVID-19 patients, fatty liver was graded ultrasonographically, and the relationship between the De Ritis rate and the correlation was compared. Results: De Ritis rate was found to be significant between patients with and without COVID-19 infection. De Riti's rate of patients with COVID-19 infection was found to be significantly lower. De Ritis rate was found to be considerably lower in men with COVID-19 infection than in women with COVID-19 infection. When the GRADEs of COVID-19 patients with NAFLD and non-patient groups were compared, no statistical difference was detected. Conclusion: The De Ritis rate was significant between patients with and without COVID-19 infection, and the significantly low De Ritis rate in patients with COVID-19 infection revealed that COVID-19 disease reduced the rate of De Ritis. When the GRADEs of COVID-19 patients with NAFLD were compared with non-patient groups, the lack of statistical difference revealed that COVID-19 infection did not affect the fatty liver.

Keywords

References

  1. Ak G. (2020). COVID-19’un Klinik ve Radyolojik Özellikleri. ESTÜDAM Halk Sağlığı Dergisi, 5(COVID-19 Özel Sayısı):61-69.
  2. Botros M, Sikaris KA. (2013). The de ritis ratio: The test of time. Clin Biochem Rev, 34:117-30. Çelik D, Köse Ş. (2020). Erişkinlerde COVID-19: Klinik bulgular. Tepecik Eğit. ve Araşt. Hast. Dergisi, 30(Ek sayı):43-48.
  3. Çolak Y, Tuncer İ. (2010). Nonalkolik Karaciğer Yağlanması Ve Steatohepatit. İst Tıp Fak Derg, ;73:3:85-91. Fan Z, Chen L, Li J, Cheng X, Yang J, Tian C. (2020). Clinical Features of COVID-19-Related Liver Functional Abnormality. Clin Gastroenterol Hepatol, 18(7):1561-1566. doi: 10.1016/j.cgh.2020.04.002.
  4. Fu L, Wang B, Yuan T. (2020). Clinical characteristics of coronavirus disease 2019 (COVID 19) In China: A systematic review and meta-analysis. J Infect, 80(6):656-665. doi:10.1016/j.jinf.2020.03.041
  5. Gordon DE, Jang GM, Bouhaddou M, Xu J, Oberner K, White KM. (2020). A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature, 583;459–468. doi.org/10.1038/s41586-020-2286-9
  6. Gorgel SN. (2017). The prognostic significance of preoperatively assessed AST/ALT (De Ritis) ratio on survival in patients underwent radical cystectomy. International Urology and Nephrology, 49(9):1577–1583.
  7. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Yl. (2020). Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet, 395;497-506. doi:10.1016/S0140- 6736(20)30183-5
  8. Ikeda T. 2020. The De Ritis (aspartate transaminase/alanine transaminase) ratio as a prognosticator in patients with end-stage renal disease-associated renal cell carcinoma. Clinical Genitourinary Cancer, 18(3):236–240.

Details

Primary Language

English

Subjects

Public Health, Environmental Health

Journal Section

Research Article

Early Pub Date

June 29, 2023

Publication Date

June 30, 2023

Submission Date

May 29, 2023

Acceptance Date

June 7, 2023

Published in Issue

Year 2023 Volume: 5 Number: 1

APA
Özdin, M. (2023). The Relationship Between De Ritis Rate and Fatty Liver in Covid-19 Patients. Doğal Yaşam Tıbbı Dergisi, 5(1), 36-41. https://izlik.org/JA24AK27NH
AMA
1.Özdin M. The Relationship Between De Ritis Rate and Fatty Liver in Covid-19 Patients. JNLM. 2023;5(1):36-41. https://izlik.org/JA24AK27NH
Chicago
Özdin, Mehmet. 2023. “The Relationship Between De Ritis Rate and Fatty Liver in Covid-19 Patients”. Doğal Yaşam Tıbbı Dergisi 5 (1): 36-41. https://izlik.org/JA24AK27NH.
EndNote
Özdin M (June 1, 2023) The Relationship Between De Ritis Rate and Fatty Liver in Covid-19 Patients. Doğal Yaşam Tıbbı Dergisi 5 1 36–41.
IEEE
[1]M. Özdin, “The Relationship Between De Ritis Rate and Fatty Liver in Covid-19 Patients”, JNLM, vol. 5, no. 1, pp. 36–41, June 2023, [Online]. Available: https://izlik.org/JA24AK27NH
ISNAD
Özdin, Mehmet. “The Relationship Between De Ritis Rate and Fatty Liver in Covid-19 Patients”. Doğal Yaşam Tıbbı Dergisi 5/1 (June 1, 2023): 36-41. https://izlik.org/JA24AK27NH.
JAMA
1.Özdin M. The Relationship Between De Ritis Rate and Fatty Liver in Covid-19 Patients. JNLM. 2023;5:36–41.
MLA
Özdin, Mehmet. “The Relationship Between De Ritis Rate and Fatty Liver in Covid-19 Patients”. Doğal Yaşam Tıbbı Dergisi, vol. 5, no. 1, June 2023, pp. 36-41, https://izlik.org/JA24AK27NH.
Vancouver
1.Mehmet Özdin. The Relationship Between De Ritis Rate and Fatty Liver in Covid-19 Patients. JNLM [Internet]. 2023 Jun. 1;5(1):36-41. Available from: https://izlik.org/JA24AK27NH