Hydroxyapatite Synthesis and Comparison with Commercial Hydroxyapatite

Year 2016, Volume: 5 Issue: 11, 79 - 86, 21.12.2016

Yakup Budak , Medine Yıldırım Merve Örnek Oğuz Özbek

Abstract

Hydroxyapatite HAs is the most commonly used synthetic, inert, and biocompatible material having no organic substance. HA having calcium phosphate in their structures are biomaterials used in injured organs or tissues in human body. These make quick and strong recovery when used in body. Besides, due to the reproductive characteristics of bone cells like HA structure and the stability of HA material in body fluid they are commonly used in biomedical applications. HA is very similar to the mineral structure of the bones and teeth, and is often used for synthetic bone grafts production. Because of these properties, the synthesis, isolation and commercialization of this kind of materials gain great importance.  In this study, HA was synthesized with a precipitation and microwave radiation technique, and then the properties of synthesized HA are compared with the commercial HA. The characterization and comparison of the materials was made with various methods, general internal structure development and pore size relations were determined by FTIR, XRD and SEM. 

Keywords

Hydroxyapatite, Alloplast Graft, Biocompatibility, bioceramic,

References

• A. Pasinli, R. Aksoy, Yapay Kemik Uygulamaları için Hidroksiapatit, BiyoTeknoloji Elektronik Dergisi, 1 (2010), 41-51.
• V.P. Orlovskii, V.S. Komlev, S.M. Barinov, Hydroxyapatite and Hydroxyapatite- Based Ceramics, Inorganic Materials, 38 (2002), 973–984.
• M. Gümüşderelioğlu, Biyomalzemeler, Bilim ve Teknik Dergisi, TÜBİTAK, Temmuz özel sayısı, 2002.
• O. Güllü, M. Onay, Metalurji ve malzeme mühendisliğinin bilinmeyen yönü biyomalzemeler, Hurdacı Dergisi, 3, 2007.
• J.B. Park, J.D. Bronzino, Biomaterials: Principlesandapplications, CRC press, 2002.
• A. Evcin, D.B. Kepekçi, İ. Barut, Hidroksiapatit Tozlarının Plazma Sprey Yöntemiyle Paslanmaz Çelik Üzerine Kaplanması, 5. Uluslararası ileri Teknolojiler Sempozyumu (IATS’09), Karabük, 2009.
• T. Başargan, Püskürtmeli kurutucuda hidroksiapatid polimer malzemelerin Hazırlanması, İTÜ Fen Bilimleri Enstitüsü Yüksek Lisans Tezi, Kimya Mühendisliği Programı, 2010.
• T.V. Thamaraiselvi, S. Rajeswari, Biological Evaluation of Bioceramic Materials, , Trends Biomaterials of Artifical Organs, 18, 1, (2004), 9–17.
• L. Larry, H. and J. Wilson, An introduction to bioceramics, World Scientific Publishing Co., 1-25 (1993), 139-189.
• P. W. Brown, B.C. Hydroxyapatite and related materials, CRC Press, (1994), 3-45.
• E. Hasret, Hidroksiapatit sentezi, karakterizasyonu ve adsorban özelliğinin incelenmesi, İstanbul Teknik Üniversitesi, Fen bilimleri Enstitüsü, Yüksek lisans tezi, Kimya Mühendisliği, 2010.
• A. Afshar, M. Ghorbani, N. Ehsani, M.R. Saeri, C.C. Sorrell, Someimportant Factors in TheWetPrecipitationProcess Of Hydroxyapatite, Materialsand Design, 24 (2002), 197–202.
• I. Bogdanoviciene, A. Beganskiene, K. Tonsuaadu, J. Glaser, H.J. Meyer, A. Kareiva, Calcium hydroxyapatite, Ca10(PO4)6(OH)2 ceramics prepared by aqueous sol–gel processing, Materials Research Bulletin, 41 (2006), 1754– 1762.
• N.Ö. Engin, A.C. Taş¸ Preparation of Porous Ca10(PO4)6(OH)2 and b-Ca3(PO4)2 Bioceramics, J. Am. Ceram. Soc., 83 7 (2000), 1581–1584.
• Ş. Yılmaz, G.K. Delikanlı, Metalik biyomalzemelerde son gelişmeler, TİMAK- Tasarım İmalat Analiz Kongresi, İzmir, 2006.
• T.V. Safronova, M.A. Shekhirev, V.I. Putlyaev, D., Tret’yakovYu. Hydroxyapatite- Based Ceramic Materials Prepared Using Solutions of Different Concentrations, Inorganic Materials, 43 8 (2007), 901–909.