A new colorimetric sensor based on semithiocarbazone for some anions: 2-(1,3-dioxo-1,3-dihydro-2H-inden-2-ylidene)-N-phenylhydrazine-1-carbothioamide

Year 2023, Volume: 12 Issue: 2, 108 - 117, 31.08.2023

Fatma Aydın

https://doi.org/10.54187/jnrs.1338019

Abstract

Carbazones are molecules containing important functional groups in designing anion chemosensors due to proton donor and acceptor sites in their structures. In this paper, we synthesize a novel colorimetric receptor with 1,3-dioxo-indene and thiosemicarbazone moieties by the reaction of ninhydrin and 4-phenyl-thiosemicarbazide in quantitative yield. We then identify its structure by means of FT-IR, $^{1}$H-NMR, $^{13}$C-NMR, and MS spectroscopic techniques. Moreover, we observe the reaction of the title compound with biologically important F$^¯$, OAc$^¯$, CN$^¯$, H2PO4$^¯$, and OH$^¯$ anions in the presence of other anions, such as Cl$^¯$, Br$^¯$, I$^¯$, SCN$^¯$, and OCl$^¯$ in dimethylsulfoxide solution through a color change from yellow to orange-red that can easily be distinguished even by the naked eye under ambient light. Finally, we evaluate the anion-sensing ability of the title compound via UV-vis spectroscopic studies.

Keywords

4-Phenylsemithiocarbazide, Ninhydrin, Anion receptor, UV-Vis titration, Naked eye

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