Systematic Reviews and Meta Analysis
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The Relationship Between Cardiopulmonary Rehabilitation and Chronic Obstructive Pulmonary Disease (COPD): A Systematic Review

Year 2025, Volume: 1 Issue: 1, 20 - 30, 08.09.2025

Abstract

The primary objective of this systematic review was to evaluate and compare the effectiveness of Inspiratory Muscle Training (IMT) and aerobic exercise within pulmonary rehabilitation programmes for individuals with chronic obstructive pulmonary disease (COPD). Systematic searches were conducted in PubMed, Google Scholar, EBSCO SportDiscus, and Cochrane CENTRAL to identify randomized controlled trials (RCTs) that incorporated either IMT or aerobic exercise as a core component of pulmonary rehabilitation. Inclusion criteria comprised original studies involving COPD patients, with ethical approval and adherence to international guidelines. Data extraction focused on intervention timing, duration, exercise modality, and outcome measures such as dyspnea, exercise capacity, and health-related quality of life. Five RCTs met the inclusion criteria. Most studies (60%) were conducted in inpatient settings, and in 40% of cases, interventions began within 24–48 hours after hospital admission. IMT was the primary exercise modality in 60% of the studies, while aerobic exercise accounted for 40%. IMT demonstrated a notable effect in reducing dyspnea, whereas both IMT and aerobic training produced comparable improvements in exercise capacity and quality of life. Pulmonary rehabilitation is a safe and well-tolerated intervention for COPD patients. IMT and aerobic exercise are the most effective modalities, yielding similar benefits for functional outcomes and quality of life. Further research should focus on optimising the timing, duration, frequency, and intensity of these interventions.

References

  • American Thoracic Society - St. George’s Respiratory Questionnaire (SGRQ) [Internet]. Thoracic.org. 2019. Available from: https://www.thoracic.org/members/assemblies/assemblies/srn/questionaires/sgrq.php
  • Breyer MK, Breyer-Kohansal R, Funk GC, Dornhofer N, Spruit MA, Wouters EF, et al. Nordic Walking improves daily physical activities in COPD: a randomised controlled trial. Respiratory Research. 2010 Aug 22;11(1).
  • Buist AS, McBurnie MA, Vollmer WM, Gillespie S, Burney P, Mannino DM, et al. International variation in the prevalence of COPD (The BOLD Study): a population-based prevalence study. The Lancet [Internet]. 2007 Sep;370(9589):741–50. Available from: https://ohsu.pure.elsevier.com/en/publications/international-variation-in-the-prevalence-of-copd-the-bold-study--2
  • Clark CJ, Cochrane LM, Mackay E, Paton B. Skeletal muscle strength and endurance in patients with mild COPD and the effects of weight training. The European respiratory journal [Internet]. 2000 [cited 2019 Nov 17];15(1):92–7. Available from: https://www.ncbi.nlm.nih.gov/pubmed/10678627
  • Cutrim ALC, Duarte AAM, Silva-Filho AC, Dias CJ, Urtado CB, Ribeiro RM, et al. Inspiratory muscle training improves autonomic modulation and exercise tolerance in chronic obstructive pulmonary disease subjects: A randomized-controlled trial. Respiratory Physiology & Neurobiology. 2019 May;263:31–7.
  • D A, S C, C L, C B, A P, E T, et al. Global and Regional Estimates of COPD Prevalence: Systematic Review and Meta-Analysis [Internet]. Journal of global health. 2015. Available from: https://pubmed.ncbi.nlm.nih.gov/26755942/
  • Dassios T, Katelari A, Doudounakis S, Dimitriou G. Aerobic exercise and respiratory muscle strength in patients with cystic fibrosis. Respiratory Medicine. 2013 May;107(5):684–90.
  • Duong M, Islam S, Rangarajan S, Teo K, O’Byrne PM, Schünemann HJ, et al. Global differences in lung function by region (PURE): an international, community-based prospective study. The Lancet Respiratory Medicine [Internet]. 2013 Oct;1(8):599–609.
  • Emtner M, Wadell K. Effects of exercise training in patients with chronic obstructive pulmonary disease—a narrative review for FYSS (Swedish Physical Activity Exercise Prescription Book): Table 1. British Journal of Sports Medicine. 2016 Jan 28;50(6):368–71.
  • Feng Z, Wang J, Xie Y, Li J. Effects of exercise-based pulmonary rehabilitation on adults with asthma: a systematic review and meta-analysis. Respiratory Research. 2021 Jan 30;22(1).
  • Ferguson B. ACSM’s Guidelines for Exercise Testing and Prescription 9th Ed. 2014. The Journal of the Canadian Chiropractic Association [Internet]. 2014;58(3):328. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139760/
  • Funk GC, Kirchheiner K, Chris Burghuber O, Hartl S. BODE index versus GOLD classification for explaining anxious and depressive symptoms in patients with COPD – a cross-sectional study. Respiratory Research. 2009 Jan 9;10(1).
  • Gold. Gold Reports for Personal Use - Global Initiative for Chronic Obstructive Lung Disease - GOLD [Internet]. Global Initiative for Chronic Obstructive Lung Disease - GOLD. 2020. Available from: https://goldcopd.org/gold-reports/
  • Global Initiative for Chronic Obstructive Lung Disease. GLOBAL STRATEGY FOR PREVENTION, DIAGNOSIS AND MANAGEMENT OF COPD: 2023 Report [Internet]. Global Initiative for Chronic Obstructive Lung Disease - GOLD. 2023. Available from: https://goldcopd.org/2023-gold-report-2/
  • Halbert RJ, Natoli JL, Gano A, Badamgarav E, Buist AS, Mannino DM. Global burden of COPD: systematic review and meta-analysis. European Respiratory Journal [Internet]. 2006 Apr 12;28(3):523–32. Available from: https://erj.ersjournals.com/content/28/3/523
  • Hogg JC, McDonough JE, Suzuki M. Small Airway Obstruction in COPD. Chest. 2013 May;143(5):1436–43.
  • Holland AE, Hill CJ, Conron M, Munro P, McDonald CF. Short term improvement in exercise capacity and symptoms following exercise training in interstitial lung disease. Thorax [Internet]. 2008 Feb 1;63(6):549–54. Available from: https://thorax.bmj.com/content/63/6/549.short
  • Jones PW, Tabberer M, Chen WH. Creating scenarios of the impact of copd and their relationship to copd assessment test (CATTM) scores. BMC Pulmonary Medicine. 2011 Aug 11;11(1).
  • KATSURA H, YAMADA K, WAKABAYASHI R, KIDA K. The impact of dyspnoea and leg fatigue during exercise on health-related quality of life in patients with COPD. Respirology. 2005 Sep;10(4):485–90.
  • Labaki WW, Rosenberg SR. Chronic Obstructive Pulmonary Disease. Annals of Internal Medicine. 2020 Aug 4;173(3):ITC17–32.
  • Langer D, Ciavaglia C, Faisal A, Webb KA, Neder JA, Gosselink R, et al. Inspiratory muscle training reduces diaphragm activation and dyspnea during exercise in COPD. Journal of Applied Physiology. 2018 Aug 1;125(2):381–92.
  • Li Y, Ji Z, Wang Y, Li X, Xie Y. Breathing Exercises in the Treatment of COPD: An Overview of Systematic Reviews. International Journal of Chronic Obstructive Pulmonary Disease. 2022 Dec;Volume 17:3075–85.
  • Matos Casano HA, Anjum F. Six Minute Walk Test [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2022. Available from: https://www.ncbi.nlm.nih.gov/books/NBK576420/#:~:text=Among%20these%2C%20the%206%2Dminute
  • Mathers CD, Loncar D. Projections of Global Mortality and Burden of Disease from 2002 to 2030. Samet J, editor. PLoS Medicine. 2006 Nov 28;3(11):e442.
  • Menezes AMB, Perez-Padilla R, Jardim JRB, Muiño A, Lopez MV, Valdivia G, et al. Chronic obstructive pulmonary disease in five Latin American cities (the PLATINO study): a prevalence study. Lancet (London, England) [Internet]. 2005 Nov 26;366(9500):1875–81. Available from: https://pubmed.ncbi.nlm.nih.gov/16310554/
  • McCarthy B, Casey D, Devane D, Murphy K, Murphy E, Lacasse Y. Pulmonary Rehabilitation for Chronic Obstructive Pulmonary Disease. Cochrane Database of Systematic Reviews. 2015 Feb 24;2(2).
  • Mehani SH. Comparative study of two different respiratory training protocols in elderly patients with chronic obstructive pulmonary disease. Clinical Interventions in Aging. 2017 Oct;Volume 12:1705–15.
  • Newall C. Exercise training and inspiratory muscle training in patients with bronchiectasis. Thorax. 2005 Nov 1;60(11):943–8.
  • NISHIYAMA O, KONDOH Y, KIMURA T, KATO K, KATAOKA K, OGAWA T, et al. Effects of pulmonary rehabilitation in patients with idiopathic pulmonary fibrosis. Respirology [Internet]. 2008 May;13(3):394–9. Available from: https://onlinelibrary.wiley.com/doi/10.1111/j.1440-1843.2007.01205.x
  • Page MJ, Moher D, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. PRISMA 2020 Explanation and elaboration: Updated Guidance and Exemplars for Reporting Systematic Reviews. BMJ [Internet]. 2021 Mar 29;372(160). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005925/
  • Porszasz J, Emtner M, Goto S, Somfay A, Whipp BJ, Casaburi R. Exercise Training Decreases Ventilatory Requirements and Exercise-Induced Hyperinflation at Submaximal Intensities in Patients With COPD. Chest. 2005 Oct;128(4):2025–34.
  • PRISMA 2020 Explanation and elaboration: Updated Guidance and Exemplars for Reporting Systematic Reviews. BMJ. 2021;372:160.
  • Rochester CL, Vogiatzis I, Holland AE, Lareau SC, Marciniuk DD, Puhan MA, et al. An Official American Thoracic Society/European Respiratory Society Policy Statement: Enhancing Implementation, Use, and Delivery of Pulmonary Rehabilitation. American Journal of Respiratory and Critical Care Medicine. 2015 Dec;192(11):1373–86.
  • Rochester CL, Vogiatzis I, Holland AE, Lareau SC, Marciniuk DD, Puhan MA, et al. An Official American Thoracic Society/European Respiratory Society Policy Statement: Enhancing Implementation, Use, and Delivery of Pulmonary Rehabilitation. American Journal of Respiratory and Critical Care Medicine. 2015 Dec;192(11):1373–86.
  • Roth GA, Abate D, Abate KH, Abay SM, Abbafati C, Abbasi N, et al. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet [Internet]. 2018 Nov;392(10159):1736–88. Available from: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)32203-7/fulltext
  • Schultz K, Jelusic D, Wittmann M, Krämer B, Huber V, Fuchs S, et al. Inspiratory muscle training does not improve clinical outcomes in 3-week COPD rehabilitation: results from a randomised controlled trial. European Respiratory Journal. 2018 Jan;51(1):1702000.
  • Seladi-Schulman J. What to Know about Impaired Gas Exchange in COPD [Internet]. Healthline. 2021. Available from: https://www.healthline.com/health/copd/impaired-gas-exchange-related-to-copd
  • Spruit MA, Singh SJ, Garvey C, ZuWallack R, Nici L, Rochester C, et al. An Official American Thoracic Society/European Respiratory Society Statement: Key Concepts and Advances in Pulmonary Rehabilitation. American Journal of Respiratory and Critical Care Medicine [Internet]. 2013 Oct 15;188(8):e13–64. Available from: https://pubmed.ncbi.nlm.nih.gov/24127811/
  • Spruit MA, Singh SJ, Rochester CL, Greening NJ, Franssen FME, Pitta F, et al. Pulmonary rehabilitation for patients with COPD during and after an exacerbation-related hospitalisation: back to the future? European Respiratory Journal. 2018 Jan;51(1):1701312.
  • Ubolnuar N, Tantisuwat A, Thaveeratitham P, Lertmaharit S, Kruapanich C, Mathiyakom W. Effects of Breathing Exercises in Patients With Chronic Obstructive Pulmonary Disease: Systematic Review and Meta-Analysis. Annals of Rehabilitation Medicine [Internet]. 2019 Aug 1;43(4):509–23. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734022/
  • Vos T, Lim SS, Abbafati C, Abbas KM, Abbasi M, Abbasifard M, et al. Global Burden of 369 Diseases and Injuries in 204 Countries and territories, 1990–2019: a Systematic Analysis for the Global Burden of Disease Study 2019. The Lancet [Internet]. 2020 Oct 17;396(10258):1204–22. Available from: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30925-9/fulltext
  • Wedzicha JA, Miravitlles M, Hurst JR, Calverley PMA, Albert RK, Anzueto A, et al. Management of COPD exacerbations: a European Respiratory Society/American Thoracic Society guideline. European Respiratory Journal. 2017 Mar;49(3):1600791.
  • Wootton SL, Hill K, Alison JA, Ng LWC, Jenkins S, Eastwood PR, et al. Effects of ground-based walking training on daily physical activity in people with COPD: A randomised controlled trial. Respiratory Medicine. 2017 Nov;132:139–45.
  • Xiao L, Duan H, Li P, Wu W, Shan C, Liu X. A systematic review and meta-analysis of Liuzijue in stable patients with chronic obstructive pulmonary disease. BMC Complementary Medicine and Therapies. 2020 Oct 14;20(1).
  • WHO. Mortality and global health estimates [Internet]. www.who.int. 2016. Available from: https://www.who.int/data/gho/data/themes/mortality-and-global-health-estimates
  • World Health Organization. World Health Organization [Internet]. Who.int. World Health Organization; 2023. Available from: https://www.who.int/ 58(3):328.

Year 2025, Volume: 1 Issue: 1, 20 - 30, 08.09.2025

Abstract

References

  • American Thoracic Society - St. George’s Respiratory Questionnaire (SGRQ) [Internet]. Thoracic.org. 2019. Available from: https://www.thoracic.org/members/assemblies/assemblies/srn/questionaires/sgrq.php
  • Breyer MK, Breyer-Kohansal R, Funk GC, Dornhofer N, Spruit MA, Wouters EF, et al. Nordic Walking improves daily physical activities in COPD: a randomised controlled trial. Respiratory Research. 2010 Aug 22;11(1).
  • Buist AS, McBurnie MA, Vollmer WM, Gillespie S, Burney P, Mannino DM, et al. International variation in the prevalence of COPD (The BOLD Study): a population-based prevalence study. The Lancet [Internet]. 2007 Sep;370(9589):741–50. Available from: https://ohsu.pure.elsevier.com/en/publications/international-variation-in-the-prevalence-of-copd-the-bold-study--2
  • Clark CJ, Cochrane LM, Mackay E, Paton B. Skeletal muscle strength and endurance in patients with mild COPD and the effects of weight training. The European respiratory journal [Internet]. 2000 [cited 2019 Nov 17];15(1):92–7. Available from: https://www.ncbi.nlm.nih.gov/pubmed/10678627
  • Cutrim ALC, Duarte AAM, Silva-Filho AC, Dias CJ, Urtado CB, Ribeiro RM, et al. Inspiratory muscle training improves autonomic modulation and exercise tolerance in chronic obstructive pulmonary disease subjects: A randomized-controlled trial. Respiratory Physiology & Neurobiology. 2019 May;263:31–7.
  • D A, S C, C L, C B, A P, E T, et al. Global and Regional Estimates of COPD Prevalence: Systematic Review and Meta-Analysis [Internet]. Journal of global health. 2015. Available from: https://pubmed.ncbi.nlm.nih.gov/26755942/
  • Dassios T, Katelari A, Doudounakis S, Dimitriou G. Aerobic exercise and respiratory muscle strength in patients with cystic fibrosis. Respiratory Medicine. 2013 May;107(5):684–90.
  • Duong M, Islam S, Rangarajan S, Teo K, O’Byrne PM, Schünemann HJ, et al. Global differences in lung function by region (PURE): an international, community-based prospective study. The Lancet Respiratory Medicine [Internet]. 2013 Oct;1(8):599–609.
  • Emtner M, Wadell K. Effects of exercise training in patients with chronic obstructive pulmonary disease—a narrative review for FYSS (Swedish Physical Activity Exercise Prescription Book): Table 1. British Journal of Sports Medicine. 2016 Jan 28;50(6):368–71.
  • Feng Z, Wang J, Xie Y, Li J. Effects of exercise-based pulmonary rehabilitation on adults with asthma: a systematic review and meta-analysis. Respiratory Research. 2021 Jan 30;22(1).
  • Ferguson B. ACSM’s Guidelines for Exercise Testing and Prescription 9th Ed. 2014. The Journal of the Canadian Chiropractic Association [Internet]. 2014;58(3):328. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139760/
  • Funk GC, Kirchheiner K, Chris Burghuber O, Hartl S. BODE index versus GOLD classification for explaining anxious and depressive symptoms in patients with COPD – a cross-sectional study. Respiratory Research. 2009 Jan 9;10(1).
  • Gold. Gold Reports for Personal Use - Global Initiative for Chronic Obstructive Lung Disease - GOLD [Internet]. Global Initiative for Chronic Obstructive Lung Disease - GOLD. 2020. Available from: https://goldcopd.org/gold-reports/
  • Global Initiative for Chronic Obstructive Lung Disease. GLOBAL STRATEGY FOR PREVENTION, DIAGNOSIS AND MANAGEMENT OF COPD: 2023 Report [Internet]. Global Initiative for Chronic Obstructive Lung Disease - GOLD. 2023. Available from: https://goldcopd.org/2023-gold-report-2/
  • Halbert RJ, Natoli JL, Gano A, Badamgarav E, Buist AS, Mannino DM. Global burden of COPD: systematic review and meta-analysis. European Respiratory Journal [Internet]. 2006 Apr 12;28(3):523–32. Available from: https://erj.ersjournals.com/content/28/3/523
  • Hogg JC, McDonough JE, Suzuki M. Small Airway Obstruction in COPD. Chest. 2013 May;143(5):1436–43.
  • Holland AE, Hill CJ, Conron M, Munro P, McDonald CF. Short term improvement in exercise capacity and symptoms following exercise training in interstitial lung disease. Thorax [Internet]. 2008 Feb 1;63(6):549–54. Available from: https://thorax.bmj.com/content/63/6/549.short
  • Jones PW, Tabberer M, Chen WH. Creating scenarios of the impact of copd and their relationship to copd assessment test (CATTM) scores. BMC Pulmonary Medicine. 2011 Aug 11;11(1).
  • KATSURA H, YAMADA K, WAKABAYASHI R, KIDA K. The impact of dyspnoea and leg fatigue during exercise on health-related quality of life in patients with COPD. Respirology. 2005 Sep;10(4):485–90.
  • Labaki WW, Rosenberg SR. Chronic Obstructive Pulmonary Disease. Annals of Internal Medicine. 2020 Aug 4;173(3):ITC17–32.
  • Langer D, Ciavaglia C, Faisal A, Webb KA, Neder JA, Gosselink R, et al. Inspiratory muscle training reduces diaphragm activation and dyspnea during exercise in COPD. Journal of Applied Physiology. 2018 Aug 1;125(2):381–92.
  • Li Y, Ji Z, Wang Y, Li X, Xie Y. Breathing Exercises in the Treatment of COPD: An Overview of Systematic Reviews. International Journal of Chronic Obstructive Pulmonary Disease. 2022 Dec;Volume 17:3075–85.
  • Matos Casano HA, Anjum F. Six Minute Walk Test [Internet]. PubMed. Treasure Island (FL): StatPearls Publishing; 2022. Available from: https://www.ncbi.nlm.nih.gov/books/NBK576420/#:~:text=Among%20these%2C%20the%206%2Dminute
  • Mathers CD, Loncar D. Projections of Global Mortality and Burden of Disease from 2002 to 2030. Samet J, editor. PLoS Medicine. 2006 Nov 28;3(11):e442.
  • Menezes AMB, Perez-Padilla R, Jardim JRB, Muiño A, Lopez MV, Valdivia G, et al. Chronic obstructive pulmonary disease in five Latin American cities (the PLATINO study): a prevalence study. Lancet (London, England) [Internet]. 2005 Nov 26;366(9500):1875–81. Available from: https://pubmed.ncbi.nlm.nih.gov/16310554/
  • McCarthy B, Casey D, Devane D, Murphy K, Murphy E, Lacasse Y. Pulmonary Rehabilitation for Chronic Obstructive Pulmonary Disease. Cochrane Database of Systematic Reviews. 2015 Feb 24;2(2).
  • Mehani SH. Comparative study of two different respiratory training protocols in elderly patients with chronic obstructive pulmonary disease. Clinical Interventions in Aging. 2017 Oct;Volume 12:1705–15.
  • Newall C. Exercise training and inspiratory muscle training in patients with bronchiectasis. Thorax. 2005 Nov 1;60(11):943–8.
  • NISHIYAMA O, KONDOH Y, KIMURA T, KATO K, KATAOKA K, OGAWA T, et al. Effects of pulmonary rehabilitation in patients with idiopathic pulmonary fibrosis. Respirology [Internet]. 2008 May;13(3):394–9. Available from: https://onlinelibrary.wiley.com/doi/10.1111/j.1440-1843.2007.01205.x
  • Page MJ, Moher D, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. PRISMA 2020 Explanation and elaboration: Updated Guidance and Exemplars for Reporting Systematic Reviews. BMJ [Internet]. 2021 Mar 29;372(160). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005925/
  • Porszasz J, Emtner M, Goto S, Somfay A, Whipp BJ, Casaburi R. Exercise Training Decreases Ventilatory Requirements and Exercise-Induced Hyperinflation at Submaximal Intensities in Patients With COPD. Chest. 2005 Oct;128(4):2025–34.
  • PRISMA 2020 Explanation and elaboration: Updated Guidance and Exemplars for Reporting Systematic Reviews. BMJ. 2021;372:160.
  • Rochester CL, Vogiatzis I, Holland AE, Lareau SC, Marciniuk DD, Puhan MA, et al. An Official American Thoracic Society/European Respiratory Society Policy Statement: Enhancing Implementation, Use, and Delivery of Pulmonary Rehabilitation. American Journal of Respiratory and Critical Care Medicine. 2015 Dec;192(11):1373–86.
  • Rochester CL, Vogiatzis I, Holland AE, Lareau SC, Marciniuk DD, Puhan MA, et al. An Official American Thoracic Society/European Respiratory Society Policy Statement: Enhancing Implementation, Use, and Delivery of Pulmonary Rehabilitation. American Journal of Respiratory and Critical Care Medicine. 2015 Dec;192(11):1373–86.
  • Roth GA, Abate D, Abate KH, Abay SM, Abbafati C, Abbasi N, et al. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet [Internet]. 2018 Nov;392(10159):1736–88. Available from: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)32203-7/fulltext
  • Schultz K, Jelusic D, Wittmann M, Krämer B, Huber V, Fuchs S, et al. Inspiratory muscle training does not improve clinical outcomes in 3-week COPD rehabilitation: results from a randomised controlled trial. European Respiratory Journal. 2018 Jan;51(1):1702000.
  • Seladi-Schulman J. What to Know about Impaired Gas Exchange in COPD [Internet]. Healthline. 2021. Available from: https://www.healthline.com/health/copd/impaired-gas-exchange-related-to-copd
  • Spruit MA, Singh SJ, Garvey C, ZuWallack R, Nici L, Rochester C, et al. An Official American Thoracic Society/European Respiratory Society Statement: Key Concepts and Advances in Pulmonary Rehabilitation. American Journal of Respiratory and Critical Care Medicine [Internet]. 2013 Oct 15;188(8):e13–64. Available from: https://pubmed.ncbi.nlm.nih.gov/24127811/
  • Spruit MA, Singh SJ, Rochester CL, Greening NJ, Franssen FME, Pitta F, et al. Pulmonary rehabilitation for patients with COPD during and after an exacerbation-related hospitalisation: back to the future? European Respiratory Journal. 2018 Jan;51(1):1701312.
  • Ubolnuar N, Tantisuwat A, Thaveeratitham P, Lertmaharit S, Kruapanich C, Mathiyakom W. Effects of Breathing Exercises in Patients With Chronic Obstructive Pulmonary Disease: Systematic Review and Meta-Analysis. Annals of Rehabilitation Medicine [Internet]. 2019 Aug 1;43(4):509–23. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734022/
  • Vos T, Lim SS, Abbafati C, Abbas KM, Abbasi M, Abbasifard M, et al. Global Burden of 369 Diseases and Injuries in 204 Countries and territories, 1990–2019: a Systematic Analysis for the Global Burden of Disease Study 2019. The Lancet [Internet]. 2020 Oct 17;396(10258):1204–22. Available from: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30925-9/fulltext
  • Wedzicha JA, Miravitlles M, Hurst JR, Calverley PMA, Albert RK, Anzueto A, et al. Management of COPD exacerbations: a European Respiratory Society/American Thoracic Society guideline. European Respiratory Journal. 2017 Mar;49(3):1600791.
  • Wootton SL, Hill K, Alison JA, Ng LWC, Jenkins S, Eastwood PR, et al. Effects of ground-based walking training on daily physical activity in people with COPD: A randomised controlled trial. Respiratory Medicine. 2017 Nov;132:139–45.
  • Xiao L, Duan H, Li P, Wu W, Shan C, Liu X. A systematic review and meta-analysis of Liuzijue in stable patients with chronic obstructive pulmonary disease. BMC Complementary Medicine and Therapies. 2020 Oct 14;20(1).
  • WHO. Mortality and global health estimates [Internet]. www.who.int. 2016. Available from: https://www.who.int/data/gho/data/themes/mortality-and-global-health-estimates
  • World Health Organization. World Health Organization [Internet]. Who.int. World Health Organization; 2023. Available from: https://www.who.int/ 58(3):328.
There are 46 citations in total.

Details

Primary Language English
Subjects Health Sciences Education and Development of Programs: Medicine, Nursing and Health Sciences
Journal Section Systematic review
Authors

Kubra Aydin 0009-0006-8730-5166

Early Pub Date September 3, 2025
Publication Date September 8, 2025
Submission Date August 10, 2025
Acceptance Date August 29, 2025
Published in Issue Year 2025 Volume: 1 Issue: 1

Cite

APA Aydin, K. (2025). The Relationship Between Cardiopulmonary Rehabilitation and Chronic Obstructive Pulmonary Disease (COPD): A Systematic Review. Journal of Baltalimanı, 1(1), 20-30.