Ramsay Hunt sendromunda kombine tedavi: Klinik ve prognozun değerlendirilmesi

Öz

Amaç: Çalışmanın amacı Ramsay Hunt sendromu tanısı alan hastaların klinik özelliklerini, tedavi ve sonuçlarını retrospektif olarak analiz etmektir. Yöntem: Ramsay Hunt sendromlu 12 hasta retrospektif olarak analiz edildi. Hastaların cinsiyeti, yaşı, tedaviye ilk başvuru süresi ve klinik sonuçları kaydedildi. Fasiyal disfonksiyonun değerlendirilmesinde House-Brackmann evreleme sistemi kullanıldı. Bütün hastalar oral steroid ve acyclovir ile tedavi edildi. Bulgular: Hastalarımızın 7'si erkek, 5'i kadın idi. Hastalarımızın yaş ortalaması 59 olarak bulundu (21-68 arası). En önemli semptom akut fasiyal paralizi idi. Hastaların tedavi öncesi House-Brackmann skalası III ile VI arasında değişmekteydi. Tüm hastalarda ilk ortalama House-Brackmann skalası değeri 4.5, tedavi sonrası 2.33 idi. House Brackmann skalası V ve VI olan hastalarda fasiyal paralizinin dönme riski daha düşüktü. Sonuç: Ramsay Hunt sendromunda, fasiyal paralizinin prognozu ilk semptomlara ve klinik bulgulara bağlıdır. Prognoz ciddi paralizi ve komorbid hastalığı olanlarda daha kötüdür.

Anahtar Kelimeler

• Ramsay Hunt sendromu, tedavi, prognoz

Combined treatment in Ramsay Hunt syndrome: evaluation of clinic and prognosis

Abstract

Objective: We retrospectively analysed clinical characteristics, treatment and outcomes of the patients with Ramsay Hunt syndrome. Methods: Twelve patients with Ramsay Hunt syndrome were analysed retrospectively. Data recorded included sex, age, time from first onset to initial treatment and clinical outcomes. The House-Brackmann scale was used to assess initial facial nerve dysfunction and final facial nerve impairment. All patients were treated with oral steroids and oral acyclovir. Results: There were 7 male and 5 female patients. Mean age was 59 (range: 21 to 68) years. The main symptom was acute facial palsy. House-Brackmann classification of facial nerve function ranged from grade III to VI before treatment. The median baseline House-Brackmann grade was 4.5 and it was 2.33 after the treatment in all patients. Recovery rate of facial palsy was lower in patients with House-Brackmann grades V and VI. Conclusion: In this syndrome, the prognosis of facial palsy depends on the initial symptoms and clinical findings. The prognosis was poorer in severe palsy and patients with comorbid disease(s).

Keywords

• Ramsay Hunt syndrome, treatment, prognosis

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