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The long-term results of the impact of rhinophototherapy on quality of life in cases with allergic rhinitis

Year 2012, Volume: 2 Issue: 2, 63 - 69, 01.06.2012
https://doi.org/10.2399/jmu.2012002004

Abstract

Objective: In this study the effects of intranasal rhinophototherapy on symptoms of allergic rhinitis, physical examination findings, and quality of life of our patients with allergic rhinitis have been investigated. Methods: Our study group consisted of the patients followed up for at least 2 years with diagnosis of allergic rhinitis in our outpatient clinic. Among them the first 100 patients who underwent nasal phototherapy from January 2006 on, and followed up by us at least one year constituted our study group. The patients presenting with complaints of rhinorrhea, nasal itching, and stuffiness had undergone all physical examinations of Ear Nose and Throat system. Specific IgE levels were determined, and skin Prick tests were performed. Results: Our study group consisted of 32 male and 69 female patients with a median age of 35.09 (range 18 to 52) years. When the responses to "The Rhinoconjunctivitis Quality of Life Questionnaire" for adults were evaluated globally, it can be concluded that phototherapy method applied had improved quality of life markedly at the end of one month, but the level of improvement did not remain the same up to 3rd months, on the contrary it decreased, and at end of one year it attenuated significantly. In the short-term the most apparent response to phototherapy was observed in nasal symptoms, restricted activities, and sleep parameters. However, ocular and non-allergic symptoms improved minimally. Conclusion: As an outcome of our study, it was detected that phototherapy improved symptoms of allergic rhinitis, and physical examination findings, and effected quality of life scores favorably. However in the long run, it was concluded that adequate responses could not be obtained.

References

  • 1. Cingi C, Cakli H, Yaz A, Songu M, Bal C. Phototherapy for allergic rhinitis: a prospective, randomized, single-blind, placebo-controlled study. Ther Adv Respir Dis 2010;4:209-13.
  • 2. Cingi C, Yaz A, Cakli H, Ozudogru E, Kecik C, Bal C. The effects of phototherapy on quality of life in allergic rhinitis cases. Eur Arch Otorhinolaryngol 2009;266:1903-8.
  • 3. Cingi C, Cakli H, Us T, et al. The prevalence of allergic rhinitis in urban and rural areas of Eskisehir-Turkey. Allergol Immunopathol (Madr) 2005;33:151-6.
  • 4. Kemeny L, Koreck A. Ultraviolet light phototherapy for allergic rhinitis. J Photochem Photobiol B 2007;87:58-65.
  • 5. Ching S, Thoma A, McCabe RE, Antony MM. Measuring outcomes in aesthetic surgery. A comprehensive review of the literature. Plast Reconstr Surg 2003;111:469-80.
  • 6. Valero A, Alonso J, Antépara I, et al. Health-related quality of life in allergic rhinitis: comparing the short form ESPRINT-15 and MiniRQLQ questionnaires. Allergy 2007;62:1372-8.
  • 7. Krutmann J. Phototherapy for atopic dermatitis. Clin Exp Dermatol 2000;25:552-8.
  • 8. Krutmann J, Morita A. Mechanisms of ultraviolet (UV) B and UVA phototherapy. J Investig Dermatol Symp Proc 1999;4:70- 2.
  • 9. Lebwohl M, Ali S. Treatment of psoriasis. Part 1. Topical therapy and phototherapy. J Am Acad Dermatol 2001;45:487-98.
  • 10. Zanolli, M. Phototherapy arsenal in the treatment of psoriasis. Dermatol Clin 2004;22:397-406.
  • 11. Leimgruber A. Allergo-immunology. Rev Med Suisse 2006;11; 2:89-92.
  • 12. Neuman I, Finkelstein Y. Narrow-band red light phototherapy in perennial allergic rhinitis and nasal polyposis. Ann Allergy Asthma Immunol 1997;78:399-406.
  • 13. Csoma Z, Koreck A, Ignacz F, et al. PUVA treatment of the nasal cavity improves the clinical symptoms of allergic rhinitis and inhibits the immediate-type hypersensitivity reaction in the skin. J Photochem Photobiol B 2006;3;83:21-6.
  • 14. Brehmer D. Endonasal phototherapy with Rhinolight for the treatment of allergic rhinitis. Expert Rev Med Devices 2010;7:21-6.
  • 15. Lee E, Koo J, Berger T. UVB phototherapy and skin cancer risk:a review of the literature. Int J Dermatol 2005;44:355-60.
  • 16. Lim JL, Stern RS. High levels of ultraviolet B exposure increase the risk of non-melanoma skin cancer in psoralen and ultraviolet A-treated patients. J Invest Dermatol 2005;124:505-13.
  • 17. Brehmer D, Schön MP. Endonasal phototherapy significantly alleviates symptoms of allergic rhinitis, but has a limited impact on the nasal mucosal immune cells. Eur Arch Otorhinolaryngol 2011;268:393-9.
  • 18. Koreck AI, Csoma Z, Bodai L, et al. Rhinophototherapy: a new therapeutic tool for the management of allergic rhinitis. J Allergy Clin Immunol 2005;115:541-7.
  • 19. Pradalier A, Neukirch C, Dreyfus I, Devillier P. Desloratadine improves quality of life and symptom severity in patients with allergic rhinitis. Allergy 2007;62:1331-4.
  • 20. Potter PC; Paediatric Levocetirizine Study Group. Efficacy and safety of levocetirizine on symptoms and health-related quality of life of children with perennial allergic rhinitis: a double-blind, placebo-controlled randomized clinical trial. Ann Allergy Asthma Immunol 2005;95:175-80.
  • 21. Riu E, Dressel H, Windstetter D, et al. First months of employment and new onset of rhinitis in adolescents. Eur Respir J 2007; 30:549-55.
  • 22. Juniper EF, Guyatt GH, Griffith LE, Ferrie PJ. Interpretation of rhinoconjunctivitis quality of life questionnaire data. J Allergy Clin Immunol 1996;98:843-5.
  • 23. Juniper EF, Riis B, Juniper BA. Development and validation of an electronic version of the Rhinoconjunctivitis Quality of Life Questionnaire. Allergy 2007;62:1091-3.
  • 24. Juniper EF, Ståhl E, Doty RL, Simons FE, Allen DB, Howarth PH. Clinical outcomes and adverse effect monitoring in allergic rhinitis. J Allergy Clin Immunol 2005;115(3 Suppl 1):390-413.

Rinofototerapinin alerjik rinitli olgularda yaşam kalitesine etkisinin uzun dönem sonuçları

Year 2012, Volume: 2 Issue: 2, 63 - 69, 01.06.2012
https://doi.org/10.2399/jmu.2012002004

Abstract

Amaç: Bu çalışmada allerjik rinitli hastalarımıza uygulanan intranazal fototerapinin, allerjik rinit semptomları, muayene bulguları ve bu hastaların yaşam kalitesi üzerine etkileri araştırılmıştır. Yöntem: Çalışma grubumuzu, polikliniğimizde alerjik rinit tanısı ile en az 2 yıldır takip edilen ve Ocak 2006 tarihinden itibaren nazal fototerapi uygulanan ve 1 yıllık takibini gerçekleştirebildiğimiz ilk 100 hasta oluşturmaktadır. Polikliniğimize burun akıntısı, burun kaşıntısı, burun tıkanıklığı şikayeti ile başvuran hastalara tüm kulak burun boğaz fizik muayeneleri yapıldı. Spesifik IgE düzeyleri saptandı ve Prick deri testi yapıldı. Bulgular: Çalışma grubumuzu oluşturan hastaların 31'i erkek, 69'u kadındı. Yaşları 18 ile 52 arasında olup, yaş ortalaması 35.09 idi. Burun ve Gözlerinde Alerjisi Olan Yetişkinler İçin Yaşam Kalitesi Soru Formu sonuçları global olarak değerlendirildiğinde uygulanan fototerapi tedavi yönteminin 1. ay sonunda yaşam kalitesini belirgin düzeyde iyileştirdiği, bu iyileşmenin 3. aya kadar aynı düzeyde devam etmeyip azaldığı ancak 1. yılda etkinin büyük ölçüde azaldığı şeklinde yorumlanabilir. Kısa dönemde fototerapiye en belirgin yanıt burun semptomları, kısıtlanan faaliyetler ve uyku parametrelerinde gözlenmiştir. En az düzelme ise okuler semptomlar ve alerji dışı semptomlarda olmuştur. Sonuç: Çalışmamız sonucunda fototerapinin kısa dönemde alerjik rinit semptom ve muayene bulgularında düzelme sağladığı, hastaların yaşam kalitesi skorlarını olumlu yönde etkileyen bir tedavi yöntemi olduğu saptandı. Ancak uzun dönemde yeterli yanıtın alınamadığı kanaatine varıldı.

References

  • 1. Cingi C, Cakli H, Yaz A, Songu M, Bal C. Phototherapy for allergic rhinitis: a prospective, randomized, single-blind, placebo-controlled study. Ther Adv Respir Dis 2010;4:209-13.
  • 2. Cingi C, Yaz A, Cakli H, Ozudogru E, Kecik C, Bal C. The effects of phototherapy on quality of life in allergic rhinitis cases. Eur Arch Otorhinolaryngol 2009;266:1903-8.
  • 3. Cingi C, Cakli H, Us T, et al. The prevalence of allergic rhinitis in urban and rural areas of Eskisehir-Turkey. Allergol Immunopathol (Madr) 2005;33:151-6.
  • 4. Kemeny L, Koreck A. Ultraviolet light phototherapy for allergic rhinitis. J Photochem Photobiol B 2007;87:58-65.
  • 5. Ching S, Thoma A, McCabe RE, Antony MM. Measuring outcomes in aesthetic surgery. A comprehensive review of the literature. Plast Reconstr Surg 2003;111:469-80.
  • 6. Valero A, Alonso J, Antépara I, et al. Health-related quality of life in allergic rhinitis: comparing the short form ESPRINT-15 and MiniRQLQ questionnaires. Allergy 2007;62:1372-8.
  • 7. Krutmann J. Phototherapy for atopic dermatitis. Clin Exp Dermatol 2000;25:552-8.
  • 8. Krutmann J, Morita A. Mechanisms of ultraviolet (UV) B and UVA phototherapy. J Investig Dermatol Symp Proc 1999;4:70- 2.
  • 9. Lebwohl M, Ali S. Treatment of psoriasis. Part 1. Topical therapy and phototherapy. J Am Acad Dermatol 2001;45:487-98.
  • 10. Zanolli, M. Phototherapy arsenal in the treatment of psoriasis. Dermatol Clin 2004;22:397-406.
  • 11. Leimgruber A. Allergo-immunology. Rev Med Suisse 2006;11; 2:89-92.
  • 12. Neuman I, Finkelstein Y. Narrow-band red light phototherapy in perennial allergic rhinitis and nasal polyposis. Ann Allergy Asthma Immunol 1997;78:399-406.
  • 13. Csoma Z, Koreck A, Ignacz F, et al. PUVA treatment of the nasal cavity improves the clinical symptoms of allergic rhinitis and inhibits the immediate-type hypersensitivity reaction in the skin. J Photochem Photobiol B 2006;3;83:21-6.
  • 14. Brehmer D. Endonasal phototherapy with Rhinolight for the treatment of allergic rhinitis. Expert Rev Med Devices 2010;7:21-6.
  • 15. Lee E, Koo J, Berger T. UVB phototherapy and skin cancer risk:a review of the literature. Int J Dermatol 2005;44:355-60.
  • 16. Lim JL, Stern RS. High levels of ultraviolet B exposure increase the risk of non-melanoma skin cancer in psoralen and ultraviolet A-treated patients. J Invest Dermatol 2005;124:505-13.
  • 17. Brehmer D, Schön MP. Endonasal phototherapy significantly alleviates symptoms of allergic rhinitis, but has a limited impact on the nasal mucosal immune cells. Eur Arch Otorhinolaryngol 2011;268:393-9.
  • 18. Koreck AI, Csoma Z, Bodai L, et al. Rhinophototherapy: a new therapeutic tool for the management of allergic rhinitis. J Allergy Clin Immunol 2005;115:541-7.
  • 19. Pradalier A, Neukirch C, Dreyfus I, Devillier P. Desloratadine improves quality of life and symptom severity in patients with allergic rhinitis. Allergy 2007;62:1331-4.
  • 20. Potter PC; Paediatric Levocetirizine Study Group. Efficacy and safety of levocetirizine on symptoms and health-related quality of life of children with perennial allergic rhinitis: a double-blind, placebo-controlled randomized clinical trial. Ann Allergy Asthma Immunol 2005;95:175-80.
  • 21. Riu E, Dressel H, Windstetter D, et al. First months of employment and new onset of rhinitis in adolescents. Eur Respir J 2007; 30:549-55.
  • 22. Juniper EF, Guyatt GH, Griffith LE, Ferrie PJ. Interpretation of rhinoconjunctivitis quality of life questionnaire data. J Allergy Clin Immunol 1996;98:843-5.
  • 23. Juniper EF, Riis B, Juniper BA. Development and validation of an electronic version of the Rhinoconjunctivitis Quality of Life Questionnaire. Allergy 2007;62:1091-3.
  • 24. Juniper EF, Ståhl E, Doty RL, Simons FE, Allen DB, Howarth PH. Clinical outcomes and adverse effect monitoring in allergic rhinitis. J Allergy Clin Immunol 2005;115(3 Suppl 1):390-413.
There are 24 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Aytekin Yaz This is me

Cemal Cingi This is me

Melek Kezban Gürbüz This is me

Cengiz Bal This is me

Publication Date June 1, 2012
Published in Issue Year 2012 Volume: 2 Issue: 2

Cite

APA Yaz, A., Cingi, C., Gürbüz, M. K., Bal, C. (2012). Rinofototerapinin alerjik rinitli olgularda yaşam kalitesine etkisinin uzun dönem sonuçları. Journal of Medical Updates, 2(2), 63-69. https://doi.org/10.2399/jmu.2012002004
AMA Yaz A, Cingi C, Gürbüz MK, Bal C. Rinofototerapinin alerjik rinitli olgularda yaşam kalitesine etkisinin uzun dönem sonuçları. Journal of Medical Updates. June 2012;2(2):63-69. doi:10.2399/jmu.2012002004
Chicago Yaz, Aytekin, Cemal Cingi, Melek Kezban Gürbüz, and Cengiz Bal. “Rinofototerapinin Alerjik Rinitli Olgularda yaşam Kalitesine Etkisinin Uzun dönem sonuçları”. Journal of Medical Updates 2, no. 2 (June 2012): 63-69. https://doi.org/10.2399/jmu.2012002004.
EndNote Yaz A, Cingi C, Gürbüz MK, Bal C (June 1, 2012) Rinofototerapinin alerjik rinitli olgularda yaşam kalitesine etkisinin uzun dönem sonuçları. Journal of Medical Updates 2 2 63–69.
IEEE A. Yaz, C. Cingi, M. K. Gürbüz, and C. Bal, “Rinofototerapinin alerjik rinitli olgularda yaşam kalitesine etkisinin uzun dönem sonuçları”, Journal of Medical Updates, vol. 2, no. 2, pp. 63–69, 2012, doi: 10.2399/jmu.2012002004.
ISNAD Yaz, Aytekin et al. “Rinofototerapinin Alerjik Rinitli Olgularda yaşam Kalitesine Etkisinin Uzun dönem sonuçları”. Journal of Medical Updates 2/2 (June 2012), 63-69. https://doi.org/10.2399/jmu.2012002004.
JAMA Yaz A, Cingi C, Gürbüz MK, Bal C. Rinofototerapinin alerjik rinitli olgularda yaşam kalitesine etkisinin uzun dönem sonuçları. Journal of Medical Updates. 2012;2:63–69.
MLA Yaz, Aytekin et al. “Rinofototerapinin Alerjik Rinitli Olgularda yaşam Kalitesine Etkisinin Uzun dönem sonuçları”. Journal of Medical Updates, vol. 2, no. 2, 2012, pp. 63-69, doi:10.2399/jmu.2012002004.
Vancouver Yaz A, Cingi C, Gürbüz MK, Bal C. Rinofototerapinin alerjik rinitli olgularda yaşam kalitesine etkisinin uzun dönem sonuçları. Journal of Medical Updates. 2012;2(2):63-9.