Comparison of Visual Fields of Medically and Surgically Regulated Open-Angle Glaucoma Patients

Year 2016, Volume: 2 Issue: 3, 0 - 0, 29.09.2016

Hakan Baybora İbrahim Koçer Faruk Kaya İbrahim Koçak Hacı Koç

Abstract

Amaç: Oküler tansiyonları cerrahi veya medical tedaviyle regüle olan primer açık açılı glokomlu olguların görme alanı değişikliklerinin iki yıllık takipte
farklılık gösterip göstermediğinin tespit edilmesi.
Materyal ve
Method:
2011 -20013 yılları arasında kliniğimizde primer açık açılı glokom nedeniyle opera edilmiş 17 ve tıbbi tedavi gören 21 hasta dahil edildi. Rutin
oftalmolojik muayeneleri ve ön kamara açısının değerlendirilmesi yapıldı. Tüm hastaların başlangıç ve her 3 ayda bir Humphrey 30-2 görme
alanı muayeneleri yapıldı. Görmealanları yanında görmealanı değişimlerinin istatistiksel olarak değerlendirilmesi için cihazın glokom ilerleme
analizi programı kullanıldı. Hastaların yaşları arasındaki fark t- testi, görme alanındaki kötüleşmelerin karşılaştırılması ise Fisher’inkesin K2
testiyle yapıldı. Vizyon ve tansiyonlar her iki grupta karşılaştırılırken unpaired t-test kullanıldı.
Sonuç: Her iki gruptada görülen görme alanı kötüleşmelerini gösteren kötüleşme analizleri arasında anlamlı birfark görülmedi (p=0.49, p>0.05).

References

• Denny M, Taylor F. Introduction and definitions. Section 10. In:Cantor L,Berlin MS, Hodapp EA, Lee DA, Wilson MR, ed Glaucoma,Basic and ClinicalScience Course. American Academy of Ophthalmology. San Francisco1999-2000: 7-9.
• Denny M, Taylor F. Introduction and definitions. Section 10. In: Cantor L,Berlin MS, Hodapp EA, Lee DA, Wilson MR, ed Glaucoma,Basic and ClinicalScience Course. American Academy of Ophthalmology. San Francisco1999-2000: 104-105.
• Denny M, Taylor F. Introduction and definitions. Section 10. In:Cantor L,Berlin MS, Hodapp EA, Lee DA, Wilson MR, ed Glaucoma,Basic and
• Clinical Science Course. American Academy of Ophthalmology San
• Francisco 1999-2000: 114-115.
• Cairns JE. Trabeculectomy. Preliminary report of a new method. Am J
• Ophthalmol 1968;5:673-679
• Leske MC, Heijl A,Hymen L, Bengtson B. Early Manifest Glaucoma Trial:Design and Baseline data. Ophthalmology 1999;106:2144-2153.
• Advanced Glaucoma Intervention Study 2: Visual field test scoring and
• reliability. Ophthalmology 1999;101:1445-1455
• Musch DC, Lichter PR, Guire KE, Standardi CL, CIGTS Study Group. TheCollaboration Initial Glaucoma Treatment Study: Study design, methods,and baseline characteristics of enrolled patients. Ophthalmology
• ;106:653-662.
• Mao LK, Steward WC, Shields MB. Correlation between intraocular
• pressure control and Progressive Galucomatous damage in primary open
• angle glaucoma. Am J Ophthalmol 1991;111:51-5.
• Maier PC, Funk J, Schwarzer G, Antes G, Flack-Ytter YT. Treathment
• of ocular hypertension and open angle glaucoma meta-analysis of
• randomized controlled trials. BMJ 2005;331(7509):134-139.
• Leske MC, Heijl A, Hussein, et al. Factors for glaucoma progression and theeffect of treathment: the Early Manifest Glaucoma Trial. Arch Ophthalmol2003;121(1):48-56.
• The AGIS Investigators. The Advanced Glaucoma Intervention Study
• (AGIS):7. The relationship between control of intraocular pressure and
• visual field deterioration. Am J Ophthalmol 200;10(4):429-440.
• Chauhan BC, Mikelberg FS, Balaszi AG, et al. Risc factors for progression ofopen angle Glaucoma. Arch Ophthalmol. 2008;126(8):1030-1036.
• Messmer C, Flammer J, Stümfig D. Influence of betaxolol and timolol on thevisual field of patients with glaucoma. Am J Ophthalmol 1991;112:678-681.
• Collignen- Brach J. Long term effect of topical beta –blockers on intraocularpressure and Visual field sensitivity in chronic open angle glaucoma andocular hypertension. Survey of Ophthalmol 1994;38:156-60.
• Netland PA, Landry T, Sullivan K, Andrew R, Silver L, Weiner A, Mallick S,Dickerson J, Bergamini V.W, Robertson SM, Davis A. Travoprost comparedwith Latanoprost and Timolol in patients with open angle glaucoma orocular hypertension. Am J Ophthalmol 2001;132:472-483.
• Li T, Lindsley K, Rouse B, Hong H, Shi Q, Friedman D S, Wornald R, DickersinK.Comparative Effectiveness of First Line Medications for Primary Open-Angle Glaucoma. Ophthalmology 2016; 123:129-140.
• Liu J C, Ko C, Cheng C, Chiu AW, Chou J C, Hsu W M, Liu J H. Changes inintraocular Ocular perfusion pressure after pressure Latanoprost 0.005%or Brimonidine Tartrate 0.2% in Normal Tension Glaucoma Patients.Ophthalmology 2002; 109:2241-2247.
• Centofanti M, Oddone F, Gandolfi S, Hommer A, Boehm A, Lucia T,
• Sangermani C, Sportelli V, Haustein M, Manni G, Rossetti L. Comparison
• of Travoprost and Bimatoprost plus Timolol fixed Combinations in Open-
• Angle Glaucoma Patients Previously Treated with Latanoprost plus Timololfixed combination. Am J Ophthalmol 2010;150:575-580.
• Mao LK, Stewart WC, Shields MB, Correlation between intraocular pressurecontrol and Progressive glaucomatous damage in primary open angleglaucoma. Am J Ophthalmol 1991; 106:2144-53.
• Messmer C, Flammer J, Stümfig D. Influence of betaxolol and timolol on thevisual fields of patients with glaucoma. Am J Ophthalmol 1991;112:678-681.
• Stamper RL, Lieberman MF, Drake MV(eds). Optic nerve anatomy andpatophysiology. Diagnosis and Therapy of Glaucomas. Missoury: MosbyYear Book ,Inc.1991:415.
• Schulzer M, Mikelberg FS, Drance SM. Some observations on the retlationbetween intraocular pressure reduction and progression of visual field loss.Br J Ophthalmol 1987;71:486-8.
• Stamper RL, Lieberman MF, Drake MV(eds). Optic nevre anatomy andpathophysiology. Diagnosis and Therapy of Glaucomas. Missoury: MosbyYear Book , Inc. 1999:160.
• Stewart WC, Sine CS, LoPresto C. Surgical vs Medical management ofchronic open-angle glaucoma. Am J Ophthalmol 1996;122: 767-74.
• Katz J, Sommer A. A longitudinal study of the age-adjusted variability ofautomated visual fields. Arch Ophthalmol 1987;105:1083-6.
• Molteno ACB, Bosma NJ, Kittelson JM. Otago glaucoma surgery outcomestudy. Ophthalmology 1999;106:1742-50.
• Mills KB. Trabeculectomy, a retrospective long term follow-up of 444 cases.Br J Ophthalmol 1981;65:790-95.
• Mithchell P, Lee A J, Rochtchina E, Wang J. Open – Angle glaucoma andsystemic hypertension. J of Glaucoma 2004;13: 319-326.
• Grunwald JE, Piltz J, Hariprasad SM, Dupond J, Maguire MG. Optic nerveblood flow in glaucoma: Effect of systemic hypertension. Am J Ophthalmol1999;127: 516- 522.