Serum Asymmetric Dimethyl Arginine Level is Associated with the Pain Intensity in Primary Dysmenorrhea

Year 2017, Volume: 3 Issue: 1, 36 - 41, 30.03.2017

Nermin Akdemir , Fatma Behice Cinemre Mehmet Süha Bostancı Hakan Cinemre Orhan Ünal Selçuk Özden Arif Serhan Cevrioğlu Zübeyde Kaçal Ramazan Akdemir

Abstract

Background: Aim of this study is
the investigation of the association
between Serum Asymmetric Dimethyl Arginine (ADMA) levels and menstrual pain
intensity as assessed by Visual Analogue Scale in primary dysmenorrhea
patients.

Methods: Eighty-nine young women with
primary dysmenorrhea (PD) were selected as study group. PD pain was graded
using Visual Analogue Scale (VAS), as mild, moderate and severe. Serum ADMA levels
was measured in all subjects.

Results: Mean age of study
population was 21.08±2.21 and mean VAS score was 5.9101±2.18. Serum ADMA levels were 35.2(24) in mild,
54.0(28.7) in moderate and 56.5(32.8) in severe pain groups, (P= 0.029
and P=0.001, respectively). Mean ADMA levels
difference were -18.8, p=0.046 in mild to moderate; -2.52, p=0. 945 in moderate
to severe and 21.32 p=0.048 in severe to mild pain groups.  

Conclusion: Menstrual pain intensity is correlated with the serum ADMA levels as assessed by
VAS pain score in PD patients

Keywords

Asymmetric Dimethyl Arginine, Pain Intensity, Primary Dysmenorrhea

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