Bağırsak Mikrobiyatası, Probiyotikler ve İrritable Bağırsak Sendromu(İBS)

Year 2017, Volume: 3 Issue: 3, 120 - 125, 28.09.2017

Cengiz Karacaer Ceyhun Varım Bilal Toka Selçuk Yaylacı Ahmet Bilal Genç

Abstract

İrritable bağırsak sendromu (İBS), karın ağrısı, rahatsızlık
hissi ve bağırsakalışkanlıklarının değişmesi gibi belirtilerle karakterize
kompleks bir hastalıktır.Son deneysel ve klinik araştırmalara dayanarak, düşük
dereceli inflamasyon, değiştirilmiş bağırsak mikrobiyatası ve bağırsak
bağışıklık sistemindeki değişikliği içermektedir.Bu etiyolojik faktörlerin İBS
patogenezinde önemli rol oynadığı öne sürülmüştür.

Bu
nedenle, değişmiş bağırsak mikrobiyotiklerinin terapötik restorasyonu İBS için
ideal bir tedavi olabilir.Temel bağırsak hastalıkları üzerine bağırsak
mikrobiyatası hakkında çok az veri vardır. Kompleks ve karşılıklı bir simbiyoz,
konakçı ile bağırsak mikrobiyatası arasındaki ilişkiyi düzenler.

Probiyotiklerin
hiç bir zarara neden olmadığı ve konak için faydalı olduğuna inanılan canlı organizmalar
olduğu düşünülmektedir. Değişik bağırsak mikrobiyotiklerinden ve bağırsak
inflamasyon bağışıklığından etkilenen İBS patogenezi nedeni olarak moleküler
mekanizmalarmevcuttur.

Bu
makalede bağırsak mikrobiyatası, probiyotikler ve İBS arasındaki  klinik araştırmaların sonuçları değerlendirilmiş
olup bilime katkıda bulunmasıamaçlanmıştır.

Keywords

Mikrobiyata, probiyotikler, irritable bağırsak sendromu(İBS)

References

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