Examination of Knowledge and Attitudes on the Use of Antibiotics

Year 2023, Volume: 4 Issue: 1, 64 - 74, 23.03.2023

Ayhan Durmuş , Cemal Sezer

https://doi.org/10.58770/joinihp.1257995

Cited By: 1

Abstract

Objective; to evaluate the knowledge and attitudes of the public regarding the use of antibiotics. Method; the population of our study consists of people residing in the city center of Sakarya. The sample of the study consists of 265 individuals who agreed to participate in the study. In the study, a form consisting of socio-demographic characteristics, Knowledge of Antibiotic Use and Attitude towards Antibiotic Use questionnaire was used as a data collection tool. Descriptive statistical methods, reliability analysis, and chi-square test were used in the analysis of the data. The data were analyzed at a 95% confidence interval (p=0.05). Results; it was found that more than half of the participants both had sufficient knowledge of antibiotic use and had a good attitude towards the use of antibiotics. A relationship was found between knowledge of antibiotic use and questions of attitude towards antibiotic use. The relationship between the Knowledge of Antibiotic Use and the Attitude towards Antibiotic Use scale and socio-demographic variables was determined. Conclusion; participants who have a good level of knowledge about antibiotic use have a positive attitude towards antibiotic use. In this context, it may be beneficial to help people develop interventions by increasing their awareness of the risks of inappropriate antibiotic use and to reduce misconceptions about antibiotic use.

Keywords

antibiotic, knowledge, attitude, rational use of antibiotics

Antibiyotik Kullanımına Yönelik Bilgi ve Tutumların İncelenmesi

Abstract

Amaç; halkın antibiyotik kullanımına ilişkin bilgi ve tutumlarının değerlendirilmektir. Yöntem; çalışmamızın evrenini Sakarya il merkezinde ikamet eden kişiler oluşturmaktadır. Çalışmanın örneklemini çalışmaya katılmayı kabul eden 265 kişi oluşturmaktadır. Çalışmada veri toplama aracı olarak sosyo – demografik özellikler ve Antibiyotik Kullanım Bilgisi ve Antibiyotik Kullanımına Yönelik Tutum anketinden oluşan form kullanılmıştır. Verilerin analizinde tanımlayıcı istatistiksel yöntemler, güvenilirlik analizi, ki-kare testi kullanılmıştır. Veriler %95 güven aralığında (p=0,05) analiz edilmiştir. Bulgular; katılımcıların yarısından fazlasının hem Antibiyotik Kullanım Bilgisinin yeterli düzeyde olduğu hem de Antibiyotik Kullanımına Yönelik iyi tutuma sahip olduğu bulunmuştur. Antibiyotik kullanım bilgisi ile antibiyotik kullanımına yönelik tutum soruları arasında ilişki tespit edilmiştir. Antibiyotik Kullanım Bilgisi ve Antibiyotik Kullanımına Yönelik Tutum ölçeği ile sosyo demografik değişkenler arasındaki ilişki belirlenmiştir. Sonuç; antibiyotik kullanımı konusunda bilgi düzeyi iyi olan katılımcılar, antibiyotik kullanımına karşı olumlu bir tutum sergilemektedir. Bu bağlamda, insanların uygunsuz antibiyotik kullanım risklerine ilişkin farkındalıklarını artırarak müdahale geliştirmelerine yardımcı olmak ve antibiyotik kullanımına ilişkin kavram yanılgılarını azaltmak yararlı olabilir.

Keywords

antibiyotik, bilgi, tutum, akılcı antibiyotik kullanımı

References

• European Centre for Disease Prevention and Control (ECDC). Facts about antimicrobial resistance. Erişim Adresi: https://www.ecdc.europa.eu/en/antimicrobial-resistance/facts Erişim Tarihi: 26.02.2023.
• [2] Sass, P. (2017). Antibiotics: Precious Goods in Changing Times. P. Sass (Ed.). Antibiotics: Methods and Protocols (s. 3-22). Methods in Molecular Biology, vol. 1520, New York: Humana Press. [3] Mazińska, B., Strużycka, I., & Hryniewicz, W. (2017). Surveys of public knowledge and attitudes with regard to antibiotics in Poland: Did the European Antibiotic Awareness Day campaigns change attitudes?. PloS one, 12(2), e0172146.
• [4] World Health Organization (WHO, 2014). Antimicrobial resistance: global report on surveillance 2014; World Health Organization: Geneva, Switzerland. Erişim Adresi: https://apps.who.int/iris/bitstream/handle/10665/112642/?sequence=1
• [5] Centers for Disease Control and Prevention. (2017). Antibiotic Use in the United States, 2017: Progress and Opportunities. Atlanta, GA: US Department of Healthand Human Services, CDC. Erişim Adresi: https://www.cdc.gov/antibiotic-use/stewardship-report/pdf/stewardship-report.pdf Erişim Tarihi: 28.02.2023
• [6] Ventola, C. L. (2015). The antibiotic resistance crisis: part 1: causes and threats. Pharmacy and therapeutics, 40(4), 277-283.
• [7] Prescott, J. F. (2014). The resistance tsunami, antimicrobial stewardship, and the golden age of microbiology. Veterinary microbiology, 171(3-4), 273-278.
• [8] Ansari, F. (2010). Evaluation and Management of Hospital Antibiotic Use. Doctor of Philosophy, University of Dundee, England.
• [9] Atik, A. D., & Doğan, Y. (2019). Antibiyotik Kullanım Ölçeği: Ölçek Geliştirme Çalışması. Van Yüzüncü Yıl Üniversitesi Eğitim Fakültesi Dergisi, 16(1), 1248-1276.
• [10] Klein, E. Y., Van Boeckel, T. P., Martinez, E. M., Pant, S., Gandra, S., Levin, S. A., ... & Laxminarayan, R. (2018). Global increase and geographic convergence in antibiotic consumption between 2000 and 2015. Proceedings of the National Academy of Sciences, 115(15), E3463-E3470.
• [11] Aksoy, M., Isli, F., Kadi, E., Varimli, D., Gursoz, H., Tolunay, T., ... & Alp Mese, E. (2021). Evaluation of more than one billion outpatient prescriptions and eight‐year trend showing a remarkable reduction in antibiotic prescription in Turkey: A success model of governmental interventions at national level. Pharmacoepidemiology and Drug Safety, 30(9), 1242-1249.
• [12] Gaygısız, Ü., Lajunen, T., & Gaygısız, E. (2021). Community use of antibiotics in Turkey: the role of knowledge, beliefs, attitudes, and health anxiety. Antibiotics, 10(10), 1171.
• [13] World Health Organization (WHO, 2018). WHO report on surveillance of antibiotic consumption: 2016-2018 early implementation. Erişim Adresi: https://apps.who.int/iris/bitstream/handle/ 10665/277359/9789241514880- eng.pdf?ua=1.
• [14] Versporten, A., Bolokhovets, G., Ghazaryan, L., Abilova, V., Pyshnik, G., Spasojevic, T., ... & Goossens, H. (2014). Antibiotic use in eastern Europe: a cross-national database study in coordination with the WHO Regional Office for Europe. The Lancet infectious diseases, 14(5), 381-387.
• [15] Türkiye İlaç ve Tıbbi Cihaz Kurumu (2014). Akılcı İlaç Kullanımı (Aik) Ulusal Eylem Planı 2014-2017. Erişim Adresi: https://bilecikism.saglik.gov.tr/Eklenti/6528/0/mevzuataik-ulusal-eylem-planipdf.pdf Erişim Tarihi: 28.02.2023
• [16] Westerling, R., Daryani, A., Gershuni, O., Czabanowska, K., Brand, H., Erdsiek, F., ... & Brzoska, P. (2020). Promoting rational antibiotic use in Turkey and among Turkish migrants in Europe–implications of a qualitative study in four countries. Globalization and health, 16(1), 1-9.
• [17] Aksoy, M., Alkan, A., & İşli, F. (2015). Rational drug use promotional activities of Ministry of Health. Turkiye Klinikleri J Pharmacol-Special Topics, 3(1), 19-26.
• [18] Kandemir Türe, A. (2021). Uygun Olmayan Cerrahi Antibiyotik Profilaksi Kullanımını ve Maliyetini Etkileyen Faktörler. Yayımlanmamış Doktora Tezi. Sosyal Bilimler Enstitüsü, Hacettepe Üniversitesi, Ankara.
• [19] Nguyen, N. V., Marothi, Y., & Sharma, M. (2022). Knowledge, Attitude, and Practice Regarding Antibiotic Use and Resistance for Upper Respiratory Tract Infections among the Population Attending a Mass Gathering in Central India: A Cross-Sectional Study. Antibiotics, 11(11), 1473 https://doi.org/10.3390/antibiotics11111473
• [20] Gould, I. M., & Bal, A. M. (2013). New antibiotic agents in the pipeline and how they can help overcome microbial resistance. Virulence, 4(2), 185-191.
• [21] Meyer, E., Gastmeier, P., Deja, M., & Schwab, F. (2013). Antibiotic consumption and resistance: data from Europe and Germany. International journal of medical microbiology : IJMM, 303(6-7), 388–395. https://doi.org/10.1016/j.ijmm.2013.04.004
• [22] Price, R. (2016). O'Neill report on antimicrobial resistance: funding for antimicrobial specialists should be improved. European Journal of Hospital Pharmacy, 23(4), 245-247.
• [23] Molina-Romera G, Vazquez-Cancela O, Vazquez-Lago JM, Montes-Villalba RA, Roque F, Herdeiro MT, Figueiras A. Knowledge, Attitudes and Practice Regarding Antibiotic Prescription by Medical Interns: A Qualitative Study in Spain. Antibiotics. 2023; 12(3):457. https://doi.org/10.3390/antibiotics12030457
• [24] Li, P., Hayat, K., Shi, L., Lambojon, K., Saeed, A., Majid Aziz, M., ... & Fang, Y. (2020). Knowledge, attitude, and practices of antibiotics and antibiotic resistance among chinese pharmacy customers: a multicenter survey study. Antibiotics, 9(4), 184
• [25] Dhingra, S., Rahman, N. A. A., Peile, E., Rahman, M., Sartelli, M., Hassali, M. A., ... & Haque, M. (2020). Microbial resistance movements: an overview of global public health threats posed by antimicrobial resistance, and how best to counter. Frontiers in Public Health, 8, 535668. doi: 10.3389/fpubh.2020.535668
• [26] Dadgostar, P. (2019). Antimicrobial resistance: implications and costs. Infection and drug resistance, 12, 3903-3910.
• [27] Li, B., & Webster, T. J. (2018). Bacteria antibiotic resistance: New challenges and opportunities for implant- associated orthopedic infections. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 36(1), 22–32. https://doi.org/10.1002/jor.23656
• [28] O’Neill, J. (2014). Review on Antimicrobial Resistance. Antimicrobial resistance: tackling a crisis for the health and wealth of nations. Erişim Adresi: https://amr-review.org/sites/default/files/AMR%20Review%20Paper%20- %20Tackling%20a%20crisis%20for%20the%20health%20and%20wealth%20of%20nations_1.pdf Erişim Tarihi: 28.02.2023
• [29] Hasan, S., Sulieman, H., Babi, H., & Bloukh, S. (2022). Development and Psychometric Evaluation of the Antibiotic Knowledge and Consumption Tool (AKCT). Antibiotics (Basel, Switzerland), 11(12), 1744. https://doi.org/10.3390/antibiotics11121744
• [30] Kim, S. S., Moon, S., & Kim, E. J. (2011). Public knowledge and attitudes regarding antibiotic use in South Korea. Journal of Korean Academy of Nursing, 41(6), 742-749.
• [31] Jorgoni, L., Camardo, E., Jeffs, L., Nakamachi, Y., Somanader, D., Bell, C. M., & Morris, A. M. (2022). Knowledge, perspectives and health outcome expectations of antibiotic therapy in hospitalized patients. Infection prevention in practice, 4(4), 100245. https://doi.org/10.1016/j.infpip.2022.100245
• [32] Yin, X., Gong, Y., Sun, N., Li, D., Wu, J., Wang, J., Qiu, L., & Li, H. (2022). Prevalence of inappropriate use behaviors of antibiotics and related factors among chinese antibiotic users: an online cross-sectional survey. BMC infectious diseases, 22(1), 689. https://doi.org/10.1186/s12879-022-07671-1
• [33] Yunita, S. L., Yang, H. W., Chen, Y. C., Kao, L. T., Lu, Y. Z., Wen, Y. L., To, S. Y., & Huang, Y. L. (2022). Knowledge and practices related to antibiotic use among women in Malang, Indonesia. Frontiers in pharmacology, 13, 1019303. https://doi.org/10.3389/fphar.2022.1019303
• [34] Alqarni, S. A., & Abdulbari, M. (2019). Knowledge and attitude towards antibiotic use within consumers in Alkharj, Saudi Arabia. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 27(1), 106–111. https://doi.org/10.1016/j.jsps.2018.09.003
• [35] Asogwa, I., Offor, S., & Mbagwu, H. (2017). Knowledge, attitude and practice towards antibiotics use among non- medical university students in Uyo, Nigeria. J Adv Med Pharm Sci, 15(1), 1-11.
• [36] Llor, C., Moragas, A., Bayona, C., Cots, J. M., Molero, J. M., Ribas, J., Fóthy, J. F., Gutiérrez, I., Sánchez, C., Ortega, J., Arranz, J., Botanes, J., & Robles, P. (2017). The STOP-AB trial protocol: efficacy and safety of discontinuing patient antibiotic treatment when physicians no longer consider it necessary. BMJ open, 7(5), e015814. https://doi.org/10.1136/bmjopen-2016-015814
• [37] Langford, B. J., & Morris, A. M. (2017). Is it time to stop counselling patients to "finish the course of antibiotics"?. Canadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPC, 150(6), 349–350. https://doi.org/10.1177/1715163517735549
• [38] Giannitsioti, E., Athanasia, S., Plachouras, D., Kanellaki, S., Bobota, F., Tzepetzi, G., & Giamarellou, H. (2016). Impact of patients’ professional and educational status on perception of an antibiotic policy campaign: a pilot study at a university hospital. Journal of global antimicrobial resistance, 6, 123-127.
• [39] McNulty, C. A., Nichols, T., Boyle, P. J., Woodhead, M., & Davey, P. (2010). The English antibiotic awareness campaigns: did they change the public's knowledge of and attitudes to antibiotic use?. Journal of Antimicrobial Chemotherapy, 65(7), 1526-1533.
• [40] McNulty, C. A., Boyle, P., Nichols, T., Clappison, P., & Davey, P. (2007). Don't wear me out—the public's knowledge of and attitudes to antibiotic use. Journal of Antimicrobial Chemotherapy, 59(4), 727-738.
• [41] You, J. H. S., Yau, B., Choi, K. C., Chau, C. T. S., Huang, O. R., & Lee, S. S. (2008). Public knowledge, attitudes and behavior on antibiotic use: A telephone survey in Hong Kong. Infection, 36, 153-157. doi: 10.1007/s15010-007- 7214-5
• [42] Lim, K. K., & Teh, C. C. (2012). A cross sectional study of public knowledge and attitude towards antibiotics in Putrajaya, Malaysia. Southern med review, 5(2), 26–33.
• [43] Simegn, W., & Moges, G. (2022). Awareness and knowledge of antimicrobial resistance and factors associated with knowledge among adults in Dessie City, Northeast Ethiopia: Community-based cross-sectional study. Plos one, 17(12), e0279342.
• [44] Wun, Y. T., Lam, T. P., Lam, K. F., Ho, P. L., & Yung, W. H. R. (2013). The public's perspectives on antibiotic resistance and abuse among Chinese in Hong Kong. Pharmacoepidemiology and drug safety, 22(3), 241-249.
• [45] Chukwu, E. E., Oladele, D. A., Awoderu, O. B., Afocha, E. E., Lawal, R. G., Abdus-Salam, I., ... & Audu, R. A. (2020). A national survey of public awareness of antimicrobial resistance in Nigeria. Antimicrobial Resistance & Infection Control, 9(72), 1-10. https://doi.org/10.1186/s13756-020-00739-0
• [46] Awad, A. I., & Aboud, E. A. (2015). Knowledge, attitude and practice towards antibiotic use among the public in Kuwait. PloS one, 10(2), e0117910.
• [47] Kainga, H., Phonera, M. C., Chikowe, I., Chatanga, E., Nyirongo, H., Luwe, M., ... & Simulundu, E. (2023). Determinants of Knowledge, Attitude, and Practices of Veterinary Drug Dispensers toward Antimicrobial Use and Resistance in Main Cities of Malawi: A Concern on Antibiotic Stewardship. Antibiotics, 12(1), 149. https://doi.org/10.3390/antibiotics12010149
• [48] Chan, Y. H., Fan, M. M., Fok, C. M., Lok, Z. L., Ni, M., Sin, C. F., ... & Schooling, C. M. (2012). Antibiotics nonadherence and knowledge in a community with the world’s leading prevalence of antibiotics resistance: implications for public health intervention. American journal of infection control, 40(2), 113-117.
• [49] Kim, W., & Park, S. (1998). Bacterial resistance to antimicrobial agents: An overview from Korea. Yonsei Medical Journal, 39, 488-494.
• [50] Di, K. N., Tay, S. T., Ponnampalavanar, S. S. S., Pham, D. T., & Wong, L. P. (2022). Socio-Demographic Factors Associated with Antibiotics and Antibiotic Resistance Knowledge and Practices in Vietnam: A Cross-Sectional Survey. Antibiotics (Basel, Switzerland), 11(4), 471. https://doi.org/10.3390/antibiotics11040471
• [51] Endashaw Hareru, H., Sisay, D., Kassaw, C., & Kassa, R. (2022). Antibiotics non-adherence and its associated factors among households in southern Ethiopia. SAGE Open Medicine, 10, 20503121221090472.
• [52] Karuniawati, H., Hassali, M. A. A., Suryawati, S., Ismail, W. I., Taufik, T., & Hossain, M. S. (2021). Assessment of knowledge, attitude, and practice of antibiotic use among the population of Boyolali, Indonesia: a cross-sectional study. International journal of environmental research and public health, 18(16), 8258.
• [53] Sindato, C., Mboera, L. E. G., Katale, B. Z., Frumence, G., Kimera, S., Clark, T. G., Legido-Quigley, H., Mshana, S. E., Rweyemamu, M. M., & Matee, M. (2020). Knowledge, attitudes and practices regarding antimicrobial use and resistance among communities of Ilala, Kilosa and Kibaha districts of Tanzania. Antimicrobial resistance and infection control, 9(1), 194. https://doi.org/10.1186/s13756-020-00862-y
• [54] André, M., Vernby, Å., Berg, J., & Lundborg, C. S. (2010). A survey of public knowledge and awareness related to antibiotic use and resistance in Sweden. Journal of Antimicrobial chemotherapy, 65(6), 1292-1296.
• [55] Grigoryan, L., Germanos, G., Zoorob, R., Juneja, S., Raphael, J. L., Paasche-Orlow, M. K., & Trautner, B. W. (2019). Use of antibiotics without a prescription in the US population: a scoping review. Annals of internal medicine, 171(4), 257-263.
• [56] Bahlas, R., Ramadan, I., Bahlas, A., Bajunaid, N., Al-Ahmadi, J., Qasem, M., & Bahy, K. (2016). Knowledge, attitude and practice towards the use of antibiotics. Life Science Journal, 13(1), 56-64.