The relationship between anti mullerian hormone level and endometrial polyp frequency in patients with polycystic ovary syndrome

Year 2022, , 263 - 267, 26.09.2022

Asena Ayar Madenli , İnci Öz , Tuğba Gürbüz

https://doi.org/10.47582/jompac.1148111

Cited By: 1

Abstract

Aim: This study aimed to conduct a case-control study to determine the relationship between serum anti mullerian hormone (AMH) levels and frequency of endometrial polyp in women with polycystic ovary syndrome (PCOS).
Material and Method: Patients with endometrial polyps (n=55) were included in the study group. The control group was selected from women without endometrial polyps (n=49). The relationship between the case and control groups was studied using the chi-square test to check the AMH levels and endometrial polyps.
Results: The participants’ age and body mass index (BMI) were 28.20±3.08 and 25.45±2.25, respectively. There was a statistically significant association between AMH levels and endometrial polyp (p-value <0.001). There was no significant difference between the endometrial polyps group and the control group in terms of age, BMI, prolactin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), dehydroepiandrosterone sulphate (DHEA-SO4), total testosterone, estradiol, thyroid-stimulating hormone (TSH) and thyroxine (T4) (p-value >0.05).
Conclusion: This research showed that the frequency of endometrial polyps increases with higher AMH levels in PCOS patients.

Keywords

Anti mullerian hormone, endometrial polyp, polycystic ovary syndrome

Polikistik over sendromlu hastalarda anti müllerian hormon düzeyi ile endometrial polip sıklığı arasındaki ilişki

Abstract

Amaç: Bu çalışmada polikistik over sendromlu (PKOS) kadınlarda serum anti mullerian hormon (AMH) düzeyleri ile endometrial polip sıklığı arasındaki ilişkiyi belirlemeyi amaçladık.
Gereç ve Yöntem: Çalışma grubuna endometrial polipli hastalar (n=55) dahil edildi. Kontrol grubu endometrial polip olmayan kadınlardan (n=49) seçildi. Olgu ve kontrol grupları arasındaki ilişki, AMH düzeylerini ve endometriyal polipleri kontrol etmek için ki-kare testi kullanılarak araştırıldı.
Bulgular: Katılımcıların yaş ve vücut kitle indeksi (VKİ) sırasıyla 28,20±3,08 ve 25,45±2,25 idi. AMH seviyeleri ile endometrial polip arasında istatistiksel olarak anlamlı bir ilişki saptandı (p değeri <0,001). Endometriyal polip grubu ile kontrol grubu arasında yaş, VKI, prolaktin, folikül uyarıcı hormon (FSH), luteinize edici hormon (LH), dehidroepiandrosteron sülfat (DHEA-SO4), total testosteron, östradiol, tiroid uyarıcı hormon (TSH) ve tiroksin (T4) değerleri açısından anlamlı farklılık saptanmadı (p değeri >0,05).
Sonuç: Bu araştırma, PKOS hastalarında yüksek AMH seviyeleri ile endometrial polip sıklığının arttığını göstermiştir.

Keywords

Anti müllerian hormone, endometrial polip, polikistik over sendromu

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