The relationship between anti mullerian hormone level and endometrial polyp frequency in patients with polycystic ovary syndrome

Abstract

Aim: This study aimed to conduct a case-control study to determine the relationship between serum anti mullerian hormone (AMH) levels and frequency of endometrial polyp in women with polycystic ovary syndrome (PCOS). Material and Method: Patients with endometrial polyps (n=55) were included in the study group. The control group was selected from women without endometrial polyps (n=49). The relationship between the case and control groups was studied using the chi-square test to check the AMH levels and endometrial polyps. Results: The participants’ age and body mass index (BMI) were 28.20±3.08 and 25.45±2.25, respectively. There was a statistically significant association between AMH levels and endometrial polyp (p-value <0.001). There was no significant difference between the endometrial polyps group and the control group in terms of age, BMI, prolactin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), dehydroepiandrosterone sulphate (DHEA-SO4), total testosterone, estradiol, thyroid-stimulating hormone (TSH) and thyroxine (T4) (p-value >0.05). Conclusion: This research showed that the frequency of endometrial polyps increases with higher AMH levels in PCOS patients.

Keywords

• Anti mullerian hormone
• endometrial polyp
• polycystic ovary syndrome

Polikistik over sendromlu hastalarda anti müllerian hormon düzeyi ile endometrial polip sıklığı arasındaki ilişki

Abstract

Amaç: Bu çalışmada polikistik over sendromlu (PKOS) kadınlarda serum anti mullerian hormon (AMH) düzeyleri ile endometrial polip sıklığı arasındaki ilişkiyi belirlemeyi amaçladık. Gereç ve Yöntem: Çalışma grubuna endometrial polipli hastalar (n=55) dahil edildi. Kontrol grubu endometrial polip olmayan kadınlardan (n=49) seçildi. Olgu ve kontrol grupları arasındaki ilişki, AMH düzeylerini ve endometriyal polipleri kontrol etmek için ki-kare testi kullanılarak araştırıldı. Bulgular: Katılımcıların yaş ve vücut kitle indeksi (VKİ) sırasıyla 28,20±3,08 ve 25,45±2,25 idi. AMH seviyeleri ile endometrial polip arasında istatistiksel olarak anlamlı bir ilişki saptandı (p değeri <0,001). Endometriyal polip grubu ile kontrol grubu arasında yaş, VKI, prolaktin, folikül uyarıcı hormon (FSH), luteinize edici hormon (LH), dehidroepiandrosteron sülfat (DHEA-SO4), total testosteron, östradiol, tiroid uyarıcı hormon (TSH) ve tiroksin (T4) değerleri açısından anlamlı farklılık saptanmadı (p değeri >0,05). Sonuç: Bu araştırma, PKOS hastalarında yüksek AMH seviyeleri ile endometrial polip sıklığının arttığını göstermiştir.

Keywords

• Anti müllerian hormone
• endometrial polip
• polikistik over sendromu

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