Hemoreoloji ve tiroid anormallikleri: eski takım oyuncusu, yeni bakış açıları

Abstract

Tiroid disfonksiyonları çeşitli fizyolojik süreçleri önemli ölçüde etkilemekte, bu etki kan akışı özelliklerine ve mikrodolaşım sistemine kadar uzanmaktadır. Bu kapsamlı derleme, tiroid bozuklukları ile hemoreoloji arasındaki kompleks ilişkiyi inceleyerek, kan akışı dinamikleri ve doku perfüzyonu üzerindeki önemli etkilerine vurgu yapmaktadır. Hipotiroidi ve hipertiroidi durumlarında kan viskozitesi, eritrosit davranışı ve mikrovasküler dolaşım üzerindeki değişikliklerin incelenmesi, bu durumların patofizyolojisine ilişkin önemli ipuçları sunmaktadır. Ayrıca, tiroid disfonksiyonları ile ilişkilendirilen hemoreolojik değişikliklerin aydınlatılması, klinik yönetim stratejilerinin geliştirilmesi için potansiyel olanaklar sunmaktadır. Bu derleme, mevcut araştırma bulgularını sentezleyerek, tiroidle ilişkili komplikasyonların karmaşıklığını anlamak için hemoreolojik yönlerin dikkate alınmasının önemini vurgulamaktadır ve tiroid disfonksiyonlarına yaklaşımda alternatif bakış açıları sunma potansiyeline sahiptir.

Keywords

• hemoreoloji
• eritrosit deformabilitesi
• eritrosit agregasyonu
• hipertiroidi
• hipotiroidi
• tiroid disfonksiyonu
• kan viskozitesi

Hemorheology in thyroid abnormalities: old team player, new insights

Abstract

Thyroid dysfunctions significantly impact various physiological processes, extending their influence on hemorheological properties and microcirculation. This comprehensive review explores the intricate relationship between thyroid disorders and hemorheology, emphasizing the substantial effects on blood flow dynamics and tissue perfusion. Examining the alterations in blood viscosity, erythrocyte behavior, and microvascular circulation in both hypothyroidism and hyperthyroidism reveals crucial insights into the pathophysiology of these conditions. Furthermore, elucidating the hemorheological changes associated with thyroid dysfunctions offers potential avenues for improved clinical management strategies. This review synthesizes current research findings, highlighting the importance of considering hemorheological aspects in understanding the complexities of thyroid-related complications and advancing patient care paradigms.

Keywords

• Hemorheology
• thyroid dysfunction
• hypothyroidism
• hyperthyroidism
• erythrocyte deformability
• erythrocyte aggregation
• blood viscosity
• plasma viscosity

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