Neurosarcoidosis

Abstract

Sarcoidosis is an autoimmune multisystemic inflammatory disease characterized by non-caseating granulomatous infection, most commonly involving the lung and lymph nodes. About 5–15% of cases involve the central nervous system (CNS), neurologic involvement in sarcoidosis is in the form of peripheral or central nervous system involvement. Recent years have seen substantial advancements in our understanding of neurosarcoidosis, including updated diagnostic standards and improved methods for treatment. We provide an overview of current developments in the identification and management of neurosarcoidosis in this review.

Keywords

• Sarcoidosis
• central nervous system
• tumor necrosis factor

Nörosarkoidoz

Abstract

Sarkoidoz en çok akciğer ve lenf bezlerini tutan, non kazeifiye granülamatöz enfeksiyonla karakterize otoimmün multisistemik inflamatuvar bir hastalıktır. Sarkoidozda nörolojik tutulum periferik ya da santral sinir sistemi tutulumu şeklindedir, görülme sıklığı %5-10 arasındadır. Son yıllarda nörosarkoidozda güncellenmiş tanı kriterleri ve tedavi yöntemlerinde önemli gelişmeler görülmüştür. Bu derlemede nörosarkoidozu tanımlama ve yönetmedeki güncel gelişmelere genel bir bakış sunulmuştur.

Keywords

• sarkoidoz
• santral sinir sistemi
• tümör nekrozis faktör

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