The relationship between in-hospital mortality rate and laboratory and radiological findings during hospital admission in children with traumatic subarachnoid hemorrhage: a retrospective cohort study

Edip Varan; Nihal Ertürk; Tamer Durdu

The relationship between in-hospital mortality rate and laboratory and radiological findings during hospital admission in children with traumatic subarachnoid hemorrhage: a retrospective cohort study

Abstract

Aims: Pediatric traumatic subarachnoid hemorrhage (tSAH) is a serious consequence of head trauma and may indicate severe brain injury. Early identification of high-risk patients is essential for timely intervention. Admission laboratory and cranial computed tomography (CT) findings may provide important prognostic information. To assess the association between admission laboratory parameters, cranial CT findings, and in-hospital mortality in pediatric patients with tSAH. Methods: This retrospective study included 51 patients under 18 years diagnosed with tSAH at a tertiary emergency department between January 2024 and January 2025. Demographic, clinical, laboratory, and CT data were collected. Mortality outcomes were compared using t-tests, Chi-square, or Fisher’s exact test. Due to the small number of deaths (n=6), analyses were considered exploratory. Results: Six patients (11.8%) died during hospitalization. Deceased patients were younger and more commonly injured in traffic accidents (p<0.05). Laboratory parameters associated with mortality included lower hemoglobin and platelet counts, higher leukocyte counts, glucose, creatinine, ALT, AST, INR, and lower arterial pH (all p<0.05). Cranial CT revealed that most deceased patients had additional intracranial injuries beyond isolated tSAH. Conclusion: Admission laboratory and cranial CT findings may be associated with in-hospital mortality in pediatric tSAH. These readily available data may support early risk stratification and clinical decision-making. Larger multicenter studies are needed to confirm these findings and further clarify their prognostic value.

Keywords

Supporting Institution

NO

Project Number

TABED 2-26-1814

Ethical Statement

The study titled "Retrospective Review of Pediatric Patients Admitted to the Emergency Department and Diagnosed with Traumatic Subarachnoid Hemorrhage," planned to be conducted at the Emergency Medicine Clinic of Ankara Bilkent City Hospital, has been reviewed and approved by the Bilkent City Hospital Ethics Committee.

Thanks

NO

References

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Details

Primary Language

English

Subjects

Neurology and Neuromuscular Diseases

Journal Section

Research Article

Authors

Edip Varan ^*
0000-0003-1018-8783
Türkiye

Nihal Ertürk
0009-0009-9800-6323
Türkiye

Tamer Durdu
0000-0002-4321-1698
Türkiye

Publication Date

June 25, 2026

Submission Date

January 13, 2026

Acceptance Date

May 3, 2026

Published in Issue

Year 2026 Volume: 7 Number: 3

IZ

https://izlik.org/JA25RE26PX

Cite

RIS / Bibtex

APA

Varan, E., Ertürk, N., & Durdu, T. (2026). The relationship between in-hospital mortality rate and laboratory and radiological findings during hospital admission in children with traumatic subarachnoid hemorrhage: a retrospective cohort study. Journal of Medicine and Palliative Care, 7(3), 469-474. https://izlik.org/JA25RE26PX

AMA

1.Varan E, Ertürk N, Durdu T. The relationship between in-hospital mortality rate and laboratory and radiological findings during hospital admission in children with traumatic subarachnoid hemorrhage: a retrospective cohort study. J Med Palliat Care / JOMPAC / jompac. 2026;7(3):469-474. https://izlik.org/JA25RE26PX

Chicago

Varan, Edip, Nihal Ertürk, and Tamer Durdu. 2026. “The Relationship Between In-Hospital Mortality Rate and Laboratory and Radiological Findings During Hospital Admission in Children With Traumatic Subarachnoid Hemorrhage: A Retrospective Cohort Study”. Journal of Medicine and Palliative Care 7 (3): 469-74. https://izlik.org/JA25RE26PX.

EndNote

Varan E, Ertürk N, Durdu T (June 1, 2026) The relationship between in-hospital mortality rate and laboratory and radiological findings during hospital admission in children with traumatic subarachnoid hemorrhage: a retrospective cohort study. Journal of Medicine and Palliative Care 7 3 469–474.

IEEE

[1]E. Varan, N. Ertürk, and T. Durdu, “The relationship between in-hospital mortality rate and laboratory and radiological findings during hospital admission in children with traumatic subarachnoid hemorrhage: a retrospective cohort study”, J Med Palliat Care / JOMPAC / jompac, vol. 7, no. 3, pp. 469–474, June 2026, [Online]. Available: https://izlik.org/JA25RE26PX

ISNAD

Varan, Edip - Ertürk, Nihal - Durdu, Tamer. “The Relationship Between In-Hospital Mortality Rate and Laboratory and Radiological Findings During Hospital Admission in Children With Traumatic Subarachnoid Hemorrhage: A Retrospective Cohort Study”. Journal of Medicine and Palliative Care 7/3 (June 1, 2026): 469-474. https://izlik.org/JA25RE26PX.

JAMA

1.Varan E, Ertürk N, Durdu T. The relationship between in-hospital mortality rate and laboratory and radiological findings during hospital admission in children with traumatic subarachnoid hemorrhage: a retrospective cohort study. J Med Palliat Care / JOMPAC / jompac. 2026;7:469–474.

MLA

Varan, Edip, et al. “The Relationship Between In-Hospital Mortality Rate and Laboratory and Radiological Findings During Hospital Admission in Children With Traumatic Subarachnoid Hemorrhage: A Retrospective Cohort Study”. Journal of Medicine and Palliative Care, vol. 7, no. 3, June 2026, pp. 469-74, https://izlik.org/JA25RE26PX.

Vancouver

1.Edip Varan, Nihal Ertürk, Tamer Durdu. The relationship between in-hospital mortality rate and laboratory and radiological findings during hospital admission in children with traumatic subarachnoid hemorrhage: a retrospective cohort study. J Med Palliat Care / JOMPAC / jompac [Internet]. 2026 Jun. 1;7(3):469-74. Available from: https://izlik.org/JA25RE26PX