Clinical characteristics, treatment patterns and survival outcomes of gynecological cancers: a single-center study from Çorum province

Seniye Burcu Torumtay Alıç; Ülkü Şimşek; Yılmaz Baş

Clinical characteristics, treatment patterns and survival outcomes of gynecological cancers: a single-center study from Çorum province

Abstract

Aims: This study aimed to evaluate the association between treatment approach, clinicopathological characteristics, tumor localization, FIGO stage, and survival outcomes in patients with gynecologic malignancies in a real-world, single-center cohort. Methods: This retrospective observational study included 196 patients diagnosed with gynecologic cancers between 2020 and 2025 at a tertiary referral center. Demographic, clinical, pathological, and survival data were collected from institutional records. Patients were analyzed according to tumor localization, histological subtype, menopausal status, comorbidity burden, FIGO stage, treatment modality, recurrence status, and overall survival. Statistical analyses included group comparisons and multivariable logistic regression to identify independent predictors of surgical treatment. Survival analysis was performed using appropriate comparative tests, and p<0.05 was considered statistically significant. Results: The mean age of the cohort was 61.18±11.78 years, and 80.1% of patients were postmenopausal. Endometrial cancer was the most common malignancy (63.8%), followed by ovarian (25.0%) and cervical cancers (8.7%). Surgical treatment was performed in 63.3% of patients. Treatment approach was significantly associated with tumor localization (p<0.001), with surgery predominating in ovarian cancer and non-surgical management more frequent in cervical cancer. FIGO stage was strongly associated with survival (p<0.001), with a marked decline in survival in advanced stages. However, no significant association was observed between treatment approach and overall survival. In multivariable analysis, menopausal status was the only independent factor associated with surgical treatment (OR=0.25, p=0.010), while age, comorbidity, and tumor location were not significant predictors. Conclusion: In gynecologic malignancies, tumor localization and FIGO stage are the primary determinants of treatment strategy and survival outcomes, respectively. While surgical treatment patterns vary according to cancer type, survival is predominantly driven by disease stage rather than patient-related factors such as age, comorbidity, or menopausal status. These findings highlight the central role of tumor biology and accurate staging in guiding clinical decision-making and prognostication.

Keywords

References

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Details

Primary Language

English

Subjects

Obstetrics and Gynaecology

Journal Section

Research Article

Authors

Seniye Burcu Torumtay Alıç ^*
0009-0007-0659-4726
Türkiye

Ülkü Şimşek
0009-0003-1439-504X
Türkiye

Yılmaz Baş
0000-0002-4229-8568
Türkiye

Publication Date

August 15, 2026

Submission Date

April 14, 2026

Acceptance Date

July 27, 2026

Published in Issue

Year 2026 Volume: 7 Number: 4

IZ

https://izlik.org/JA79RJ66ML

Cite

RIS / Bibtex

APA

Torumtay Alıç, S. B., Şimşek, Ü., & Baş, Y. (2026). Clinical characteristics, treatment patterns and survival outcomes of gynecological cancers: a single-center study from Çorum province. Journal of Medicine and Palliative Care, 7(4), 791-796. https://izlik.org/JA79RJ66ML

AMA

1.Torumtay Alıç SB, Şimşek Ü, Baş Y. Clinical characteristics, treatment patterns and survival outcomes of gynecological cancers: a single-center study from Çorum province. J Med Palliat Care / JOMPAC / jompac. 2026;7(4):791-796. https://izlik.org/JA79RJ66ML

Chicago

Torumtay Alıç, Seniye Burcu, Ülkü Şimşek, and Yılmaz Baş. 2026. “Clinical Characteristics, Treatment Patterns and Survival Outcomes of Gynecological Cancers: A Single-Center Study from Çorum Province”. Journal of Medicine and Palliative Care 7 (4): 791-96. https://izlik.org/JA79RJ66ML.

EndNote

Torumtay Alıç SB, Şimşek Ü, Baş Y (August 1, 2026) Clinical characteristics, treatment patterns and survival outcomes of gynecological cancers: a single-center study from Çorum province. Journal of Medicine and Palliative Care 7 4 791–796.

IEEE

[1]S. B. Torumtay Alıç, Ü. Şimşek, and Y. Baş, “Clinical characteristics, treatment patterns and survival outcomes of gynecological cancers: a single-center study from Çorum province”, J Med Palliat Care / JOMPAC / jompac, vol. 7, no. 4, pp. 791–796, Aug. 2026, [Online]. Available: https://izlik.org/JA79RJ66ML

ISNAD

Torumtay Alıç, Seniye Burcu - Şimşek, Ülkü - Baş, Yılmaz. “Clinical Characteristics, Treatment Patterns and Survival Outcomes of Gynecological Cancers: A Single-Center Study from Çorum Province”. Journal of Medicine and Palliative Care 7/4 (August 1, 2026): 791-796. https://izlik.org/JA79RJ66ML.

JAMA

1.Torumtay Alıç SB, Şimşek Ü, Baş Y. Clinical characteristics, treatment patterns and survival outcomes of gynecological cancers: a single-center study from Çorum province. J Med Palliat Care / JOMPAC / jompac. 2026;7:791–796.

MLA

Torumtay Alıç, Seniye Burcu, et al. “Clinical Characteristics, Treatment Patterns and Survival Outcomes of Gynecological Cancers: A Single-Center Study from Çorum Province”. Journal of Medicine and Palliative Care, vol. 7, no. 4, Aug. 2026, pp. 791-6, https://izlik.org/JA79RJ66ML.

Vancouver

1.Seniye Burcu Torumtay Alıç, Ülkü Şimşek, Yılmaz Baş. Clinical characteristics, treatment patterns and survival outcomes of gynecological cancers: a single-center study from Çorum province. J Med Palliat Care / JOMPAC / jompac [Internet]. 2026 Aug. 1;7(4):791-6. Available from: https://izlik.org/JA79RJ66ML